2005
Conditioning Injury-Induced Spinal Axon Regeneration Requires Signal Transducer and Activator of Transcription 3 Activation
Qiu J, Cafferty WB, McMahon SB, Thompson SW. Conditioning Injury-Induced Spinal Axon Regeneration Requires Signal Transducer and Activator of Transcription 3 Activation. Journal Of Neuroscience 2005, 25: 1645-1653. PMID: 15716400, PMCID: PMC6725934, DOI: 10.1523/jneurosci.3269-04.2005.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, CDAxonsAxotomyCells, CulturedCholera ToxinCytokine Receptor gp130DNA-Binding ProteinsGanglia, SpinalGAP-43 ProteinInfusion Pumps, ImplantableJanus Kinase 2MaleMembrane GlycoproteinsNerve CrushNerve RegenerationNeuritesPhosphorylationProtein Processing, Post-TranslationalProtein-Tyrosine KinasesProto-Oncogene ProteinsRatsRats, WistarSciatic NerveSignal TransductionSpinal Cord InjuriesSTAT3 Transcription FactorTrans-ActivatorsTyrphostinsConceptsSciatic nerve transectionAdult spinal cordSpinal cordSignal transducerConditioning injuryNerve transectionDorsal columnsPerineural infusionAxonal regenerationTranscription 3 (STAT3) activationDorsal root ganglion neuronsTime-dependent phosphorylationProximal nerve stumpSpinal axon regenerationTranscription factorsTranscription 3Peripheral injurySTAT3 activationDRG neuronsNerve stumpInhibitor AG490Ganglion neuronsSciatic nerveGlial scarSTAT3 phosphorylation
2002
Expression of gp130 and leukaemia inhibitory factor receptor subunits in adult rat sensory neurones: regulation by nerve injury
Gardiner NJ, Cafferty WB, Slack SE, Thompson SW. Expression of gp130 and leukaemia inhibitory factor receptor subunits in adult rat sensory neurones: regulation by nerve injury. Journal Of Neurochemistry 2002, 83: 100-109. PMID: 12358733, DOI: 10.1046/j.1471-4159.2002.01101.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, CDAxotomyBlotting, WesternCell CompartmentationCell MembraneCell NucleusCytokine Receptor gp130CytoplasmDisease Models, AnimalGanglia, SpinalLeukemia Inhibitory Factor Receptor alpha SubunitMaleMembrane GlycoproteinsNeurons, AfferentPhenotypeProtein SubunitsRatsRats, WistarReceptors, CytokineReceptors, OSM-LIFSciatic NerveSciatic NeuropathyConceptsLeukemia inhibitory factor receptorDorsal root gangliaSensory neuronesNerve injuryAdult rat sensory neuronesSmall diameter sensory neuronesReceptor subunitsSensory neuropeptide CGRPSciatic nerve axotomyMale adult ratsIL-6 cytokinesExpression of gp130Rat sensory neuronesAdult nervous systemInhibitory factor receptorNeuropeptide CGRPIL-6 familyNerve axotomySignal-transducing receptor subunitInterleukin-6 familyRoot gangliaAdult sensory neuronesLevel of gp130Isolectin B4Adult rats