2024
Patterns of sub‐optimal change following CBT for childhood anxiety
Bertie L, Arendt K, Coleman J, Cooper P, Creswell C, Eley T, Hartman C, Heiervang E, In‐Albon T, Krause K, Lester K, Marin C, Nauta M, Rapee R, Schneider S, Schniering C, Silverman W, Thastum M, Thirlwall K, Waite P, Wergeland G, Hudson J. Patterns of sub‐optimal change following CBT for childhood anxiety. Journal Of Child Psychology And Psychiatry 2024, 65: 1612-1623. PMID: 38817012, PMCID: PMC11563922, DOI: 10.1111/jcpp.14009.Peer-Reviewed Original ResearchCognitive behavioral therapyAnxiety disordersAnxiety diagnosesGrowth curve modelsMinimal respondersGroup cognitive behavioral therapyPatterns of symptom changeCurve modelClinically anxious youthSocial anxiety disorderAssociated with significantly less improvementResponse patternsAssess patterns of changeAnxious youthDisorder remissionChildhood anxietyMaternal psychopathologyBehavioral therapyDisorder severityDiagnostic statusSymptom changePre-and post-treatmentDelayed respondersAnxietyParental factors
2023
Parent Accommodation Contemporaneously Mediates the Association Between Youth Irritability and Youth Anxiety Treatment Outcome
Cabrera V, Buitron V, Patriarca G, Rey Y, Lebowitz E, Silverman W, Pettit J. Parent Accommodation Contemporaneously Mediates the Association Between Youth Irritability and Youth Anxiety Treatment Outcome. Behavior Therapy 2023, 54: 852-862. PMID: 37597962, PMCID: PMC10440415, DOI: 10.1016/j.beth.2023.03.002.Peer-Reviewed Original ResearchConceptsYouth anxiety severityParent accommodationCognitive-behavioral treatmentYouth irritabilityAnxiety treatment outcomesAnxiety severityChild anxietyPrimary anxiety disorder diagnosisAnxiety disorder diagnosisAnxious youthYouth anxietyYouth ages 6Adolescent irritabilityAnxiety outcomesBehavioral treatmentAnxiety protocolAnxietyGreater impairmentDisorder diagnosisAge 6Treatment outcomesFuture researchPosttreatmentIrritabilityResearch documentsThe Role of Family-Level Factors in Childhood Anxiety During the COVID-19 Pandemic
Kitt E, Cohodes E, McCauley S, Hommel G, Nardini C, Zacharek S, Martino A, Anderson T, Spencer H, Odriozola P, Spurrier G, Broussard A, Marin C, Silverman W, Lebowitz E, Gee D. The Role of Family-Level Factors in Childhood Anxiety During the COVID-19 Pandemic. Journal Of Emotion And Psychopathology 2023, 1: 129-151. DOI: 10.55913/joep.v1i1.18.Peer-Reviewed Original ResearchCOVID-19-related fearCOVID-19-related stressFamily-level factorsAmygdala reactivityAnxiety disordersChildren's useEmotion regulation strategiesParent-child dynamicsExpressive suppressionAnxious youthFearful facesChildhood anxietyFMRI taskPediatric anxietyRegulation strategiesOwn functioningCOVID-19 pandemicFamily exposureMultimodal studyFearPervasive disruptionChildren's exposureFamily lifeParental assistanceAnxiety
2022
Anxiety and Social Functioning: The Moderating Roles of Family Accommodation and Youth Characteristics
Etkin RG, Silverman WK, Lebowitz ER. Anxiety and Social Functioning: The Moderating Roles of Family Accommodation and Youth Characteristics. Research On Child And Adolescent Psychopathology 2022, 50: 781-794. PMID: 34997402, DOI: 10.1007/s10802-021-00884-z.Peer-Reviewed Original ResearchConceptsYouth anxiety severityFamily accommodationAnxiety severitySocial functioningYouth anxietyAnxiety disordersSocial anxiety disorder diagnosisYouth ageSocial functioning difficultiesSocial anxiety disorderYouth social functioningAnxiety disorder diagnosisHierarchical linear regressionSocial functioning variablesAnxious youthTypes of difficultiesSocial impairmentFunctioning variablesPotential moderatorsModerating RoleIntervention effortsExtent of identificationFuture research directionsDepression symptomsAnxiety
2021
Attending to the Attentional Control Scale for Children: Confirming its factor structure and measurement invariance
van Son D, Marin CE, Boutris P, Rey Y, Lebowitz ER, Pettit JW, Silverman WK. Attending to the Attentional Control Scale for Children: Confirming its factor structure and measurement invariance. Journal Of Anxiety Disorders 2021, 80: 102399. PMID: 33892347, PMCID: PMC8141040, DOI: 10.1016/j.janxdis.2021.102399.Peer-Reviewed Original ResearchConceptsAttentional Control ScaleTwo-factor modelAttentional controlControl ScaleSelf-report questionnairesTwo-factor structureStrong factorial invarianceConfirmatory factor analysisModel fitAnxious youthAttentional focusingSingle-factor modelFuture research implicationsGood model fitTwo-factorMeasurement invarianceFactorial invariancePartial invarianceFactor structureDiverse sampleConcurrent validityResearch implicationsSubscale scoresPrevious researchFactor analysis
2020
What Drives Symptom Reduction in Attention Bias Modification Treatment? A Randomized Controlled Experiment in Clinically Anxious Youths
Linetzky M, Pettit J, Silverman W, Pine D, Bar-Haim Y. What Drives Symptom Reduction in Attention Bias Modification Treatment? A Randomized Controlled Experiment in Clinically Anxious Youths. Clinical Psychological Science 2020, 8: 506-518. DOI: 10.1177/2167702620902130.Peer-Reviewed Original ResearchAttention bias modificationSpatial attentionAttention controlABM efficacyAnxious youthAnxiety symptomsAttention Bias Modification TreatmentThreat exposureClinically Anxious YouthSelective spatial attentionTreatment expectanciesAnxiety disordersSymptom reductionGroup differencesYouthLevel of changeAttentionModification treatmentControlled ExperimentMidtreatmentTreatment effectsFour-armFindingsPosttreatmentSymptoms
2019
Efficacy and mechanisms underlying a gamified attention bias modification training in anxious youth: protocol for a randomized controlled trial
Linke JO, Jones E, Pagliaccio D, Swetlitz C, Lewis KM, Silverman WK, Bar-Haim Y, Pine DS, Brotman MA. Efficacy and mechanisms underlying a gamified attention bias modification training in anxious youth: protocol for a randomized controlled trial. BMC Psychiatry 2019, 19: 246. PMID: 31391027, PMCID: PMC6686536, DOI: 10.1186/s12888-019-2224-2.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyContext of CBTBias modification trainingDot-probe taskAttentional biasAnxious youthAmygdala connectivityAnxiety disordersAttention bias modification trainingPrimary anxiety disorder diagnosisHealthy comparison youthAnxiety disorder diagnosisVisual searchThreat responsesNeurobiological correlatesComparison youthBehavioral therapyTraining elementsDisorder diagnosisEngaging gameNeuronal levelYouthPrevious findingsMixed resultsTaskTrajectories and Predictors of Response in Youth Anxiety CBT: Integrative Data Analysis
Skriner LC, Chu BC, Kaplan M, Bodden DHM, Bögels SM, Kendall PC, Nauta MH, Silverman WK, Wood JJ, Barker DH, de la Torre J, Saavedra L, Xie MG. Trajectories and Predictors of Response in Youth Anxiety CBT: Integrative Data Analysis. Journal Of Consulting And Clinical Psychology 2019, 87: 198-211. PMID: 30570308, DOI: 10.1037/ccp0000367.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyGrowth mixture modelingIntegrative data analysisParent-reported anxiety symptomsFamily cognitive-behavioral therapySymptom changeTrajectory classesYouth-reported symptomsParent-reported symptomsMixture modelingPredictors of trajectoriesItem response theory modelsAnxious youthImprovement classesAnxiety symptomsRapid respondersResponse classesYouthTheory modelPredictorsDistinct patternsOlder agePredictors of responseMembershipSymptoms
2018
Attentional Control and Threat-Related Attention Bias Partially Explain the Association Between Maternal Psychological Control and Youth Anxiety Severity
Bose D, Vaclavik D, Buitron V, Rey Y, Silverman W, Pettit J. Attentional Control and Threat-Related Attention Bias Partially Explain the Association Between Maternal Psychological Control and Youth Anxiety Severity. Cognitive Therapy And Research 2018, 43: 427-437. DOI: 10.1007/s10608-018-9982-x.Peer-Reviewed Original ResearchThreat-related attention biasMaternal psychological controlPsychological controlYouth anxietyAttention biasAttentional controlAttentional processesEtiological modelsHigh maternal psychological controlIndirect associationsYouth anxiety disordersYouth anxiety severityClinic-referred youthAnxious youthYouth ratingsAnxiety severityAnxiety disordersMothers' ratingsAnxietyLine of inquiryPotential mediatorsSeparate linesCurrent studyYouthRatingsNegative peer social interactions and oxytocin levels linked to suicidal ideation in anxious youth
Lebowitz ER, Blumberg HP, Silverman WK. Negative peer social interactions and oxytocin levels linked to suicidal ideation in anxious youth. Journal Of Affective Disorders 2018, 245: 806-811. PMID: 30699863, PMCID: PMC6361537, DOI: 10.1016/j.jad.2018.11.070.Peer-Reviewed Original ResearchConceptsNegative peer interactionsPeer social interactionSalivary oxytocin levelsAnxious youthPeer interactionsHigher oxytocin levelsAnxiety disordersOxytocin levelsSocial interactionSuicidal ideationSocial eventsSelf-report measuresPrimary anxiety disorderSemi-structured diagnostic interviewNegative social interactionsPeripheral oxytocin levelsSample of childrenPeer victimization
2017
Monotherapy Insufficient in Severe Anxiety? Predictors and Moderators in the Child/Adolescent Anxiety Multimodal Study
Taylor JH, Lebowitz ER, Jakubovski E, Coughlin CG, Silverman WK, Bloch MH. Monotherapy Insufficient in Severe Anxiety? Predictors and Moderators in the Child/Adolescent Anxiety Multimodal Study. Journal Of Clinical Child & Adolescent Psychology 2017, 47: 266-281. PMID: 28956620, PMCID: PMC6191182, DOI: 10.1080/15374416.2017.1371028.Peer-Reviewed Original ResearchConceptsChild/Adolescent Anxiety Multimodal StudyCognitive behavioral therapyModerators of outcomeSevere anxietyCombination of CBTIndependent evaluator ratingsMultimodal studyParent-rated anxietySeparation anxiety disorderMain effect findingsObsessive-compulsive disorderAnxious youthSocial anxietyChild anxietyBehavioral therapyAnxiety severityPill placeboAnxiety disordersEvaluators' ratingsAnxietyModeratorSocioeconomic statusLow socioeconomic statusYouthEffect findingsOxytocin response to youth–mother interactions in clinically anxious youth is associated with separation anxiety and dyadic behavior
Lebowitz ER, Silverman WK, Martino AM, Zagoory‐Sharon O, Feldman R, Leckman JF. Oxytocin response to youth–mother interactions in clinically anxious youth is associated with separation anxiety and dyadic behavior. Depression And Anxiety 2017, 34: 127-136. PMID: 28052452, PMCID: PMC5503301, DOI: 10.1002/da.22585.Peer-Reviewed Original ResearchConceptsSeparation anxiety disorderAnxious youthAnxiety disordersSeparation anxietySalivary oxytocinAffective touchDSM-5 anxiety disordersYouth anxiety symptomsOT responseParticular anxiety disordersAttachment figuresReliable codersMaternal sensitivityDyadic behaviorsChildren's ratingsMaternal intrusivenessAttachment behaviorAnxiety symptomsAnxiety regulationSocial supportPossible intervention strategiesSignificant distressHigher youthYouthIntervention strategies
2015
Salivary oxytocin in clinically anxious youth: Associations with separation anxiety and family accommodation
Lebowitz ER, Leckman JF, Feldman R, Zagoory-Sharon O, McDonald N, Silverman WK. Salivary oxytocin in clinically anxious youth: Associations with separation anxiety and family accommodation. Psychoneuroendocrinology 2015, 65: 35-43. PMID: 26716876, PMCID: PMC4895196, DOI: 10.1016/j.psyneuen.2015.12.007.Peer-Reviewed Original ResearchConceptsSalivary OT levelsFamily accommodationSeparation anxiety disorderYouth anxietyAnxiety disordersAnxious youthInterpersonal behaviorSeparation anxietyOT levelsDSM-5 anxiety disordersSeparation anxiety symptomsTreatment of anxietyNeuropeptide oxytocinSalivary OTClinical anxietyMaternal ratingsSalivary oxytocinAnxiety symptomsOxytocinergic systemRegulation of anxietyAnxious behaviorOwn behaviorAnxiety assessmentAnxietyParental involvementAnxiety sensitivity moderates behavioral avoidance in anxious youth
Lebowitz ER, Shic F, Campbell D, Basile K, Silverman WK. Anxiety sensitivity moderates behavioral avoidance in anxious youth. Behaviour Research And Therapy 2015, 74: 11-17. PMID: 26348546, PMCID: PMC4895193, DOI: 10.1016/j.brat.2015.08.009.Peer-Reviewed Original ResearchConceptsAnxiety sensitivityFear of spidersSensations of anxietyBehavioral avoidanceSpider stimuliAnxious youthRole of ASAvoidant behaviorAnxiety treatmentOverall avoidanceAnxietyStimuliYouthFearStrongest predictorAvoidancePatient's abilityIndividualsSensationModeratesAbilityImplicationsPredictorsSupportBehavior
2011
Sex Variations in Youth Anxiety Symptoms: Effects of Pubertal Development and Gender Role Orientation
Carter R, Silverman WK, Jaccard J. Sex Variations in Youth Anxiety Symptoms: Effects of Pubertal Development and Gender Role Orientation. Journal Of Clinical Child & Adolescent Psychology 2011, 40: 730-741. PMID: 21916691, PMCID: PMC3209758, DOI: 10.1080/15374416.2011.597082.Peer-Reviewed Original Research
2008
Measures matter: the relative contribution of anxiety and depression to suicidal ideation in clinically referred anxious youth using brief versus full length questionnaires
Carter R, Silverman WK, Allen A, Ham L. Measures matter: the relative contribution of anxiety and depression to suicidal ideation in clinically referred anxious youth using brief versus full length questionnaires. Depression And Anxiety 2008, 25: e27-e35. PMID: 18729149, DOI: 10.1002/da.20468.Peer-Reviewed Original ResearchConceptsManifest Anxiety ScaleAnxious youthChildren's Manifest Anxiety ScaleDepression InventoryIndirect effectsChildren's Depression InventoryStructural equation modelingSignificant direct effectSuicidal ideationChildhood anxietyLength versionCross-sectional designAnxiety ScaleFull-length questionnairesBrief versionEquation modelingAnxietyMeasurement strategyIdeationDepressionFull-length versionYouthDifferent findingsRelative contributionRCMAS