2010
Variation in the catechol-O-methyltransferase Val158Met polymorphism associated with conduct disorder and ADHD symptoms, among adolescent male delinquents
DeYoung CG, Getchell M, Koposov RA, Yrigollen CM, Haeffel GJ, Klinteberg B, Oreland L, Ruchkin VV, Pakstis AJ, Grigorenko EL. Variation in the catechol-O-methyltransferase Val158Met polymorphism associated with conduct disorder and ADHD symptoms, among adolescent male delinquents. Psychiatric Genetics 2010, 20: 20-24. PMID: 19997043, PMCID: PMC2895253, DOI: 10.1097/ypg.0b013e32833511e4.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderCatechol-O-methyltransferase (COMT) geneConduct disorderADHD symptomsHigh-risk populationCatechol-O-methyltransferase (COMT) Val158Met polymorphismCOMT geneDeficit/hyperactivity disorderConduct disorder diagnosisBehavior problemsSymptomsVal alleleMet alleleDisorder diagnosisHyperactivity disorderVal158Met polymorphismDisordersAntisocial behaviorAggressive behavior, related conduct problems, and variation in genes affecting dopamine turnover
Grigorenko EL, DeYoung C, Eastman M, Getchell M, Haeffel GJ, Klinteberg Ba, Koposov RA, Oreland L, Pakstis AJ, Ponomarev OA, Ruchkin VV, Singh JP, Yrigollen CM. Aggressive behavior, related conduct problems, and variation in genes affecting dopamine turnover. Aggressive Behavior 2010, 36: 158-176. PMID: 20127808, DOI: 10.1002/ab.20339.Peer-Reviewed Original Research
2007
Exploring interactive effects of genes and environments in etiology of individual differences in reading comprehension
Grigorenko EL, Deyoung CG, Getchell M, Haeffel GJ, Klinteberg BA, Koposov RA, Oreland L, Pakstis AJ, Ruchkin VV, Yrigollen CM. Exploring interactive effects of genes and environments in etiology of individual differences in reading comprehension. Development And Psychopathology 2007, 19: 1089-1103. PMID: 17931436, DOI: 10.1017/s0954579407000557.Peer-Reviewed Original ResearchConceptsIndividual differencesReading-related processesHigher-order cognitive skillsCatechol-O-methyltransferase (COMT) geneExecutive functioningCognitive processesCognitive skillsComprehension difficultiesAdolescent delinquentsMaternal rejectionComprehensionMain effectInteractive effectsImportant predictorCOMTHierarchical logistic regression modelsDelinquentsFunctioningSkillsReadingSuch processesInteraction termsPresence/absenceDifferencesPredictors