2006
Actin polymerization regulates clathrin coat maturation during early stages of synaptic vesicle recycling at lamprey synapses
Bourne J, Morgan JR, Pieribone VA. Actin polymerization regulates clathrin coat maturation during early stages of synaptic vesicle recycling at lamprey synapses. The Journal Of Comparative Neurology 2006, 497: 600-609. PMID: 16739194, DOI: 10.1002/cne.21006.Peer-Reviewed Original Research
2004
A role for talin in presynaptic function
Morgan JR, Di Paolo G, Werner H, Shchedrina VA, Pypaert M, Pieribone VA, De Camilli P. A role for talin in presynaptic function. Journal Of Cell Biology 2004, 167: 43-50. PMID: 15479735, PMCID: PMC2172527, DOI: 10.1083/jcb.200406020.Peer-Reviewed Original ResearchMeSH KeywordsActinsAnimalsBlotting, WesternCell AdhesionClathrinEndocytosisGlutathione TransferaseHumansLampreysLipid MetabolismMicroscopy, ConfocalMicroscopy, Electron, TransmissionPeptidesPhosphotransferases (Alcohol Group Acceptor)Protein BindingProtein Structure, TertiaryRatsSynapsesTalinTime FactorsConceptsSynaptic vesicle endocytosisClathrin-mediated synaptic vesicle endocytosisClathrin-coated pitsEndocytic defectsMajor phosphatidylinositolActin cytoskeletonVesicle endocytosisActin dynamicsKinase interactionTalinPIP kinasePresynaptic compartmentFunctional linkCell adhesionNeuronal synapsesEndocytosisSynaptic rolePresynaptic functionSynaptic actinActinPhosphatidylinositolSynaptic structureIgammaClathrinCytoskeletonThe role of actin in the regulation of dendritic spine morphology and bidirectional synaptic plasticity
Chen Y, Bourne J, Pieribone VA, Fitzsimonds RM. The role of actin in the regulation of dendritic spine morphology and bidirectional synaptic plasticity. Neuroreport 2004, 15: 829-832. PMID: 15073524, DOI: 10.1097/00001756-200404090-00018.Peer-Reviewed Original ResearchMeSH KeywordsActinsAnimalsBridged Bicyclo Compounds, HeterocyclicCytochalasin DDendritesElectric StimulationExcitatory Postsynaptic PotentialsHippocampusIn Vitro TechniquesMaleMicroscopy, ElectronNeuronal PlasticityNeuronsNucleic Acid Synthesis InhibitorsRatsRats, Sprague-DawleySynapsesThiazolesThiazolidinesConceptsExcitatory synaptic transmissionDendritic spine morphologySynaptic transmissionSpine morphologyRat hippocampal slicesHigh-frequency stimulationLong-term depressionBidirectional synaptic plasticityHippocampal slicesIrreversible depressionExcitatory synapsesDendritic spinesMammalian CNSSynaptic efficacySynaptic plasticityDepressionSpineCNSPotentiationSynapses
2003
Colocalization of synapsin and actin during synaptic vesicle recycling
Bloom O, Evergren E, Tomilin N, Kjaerulff O, Löw P, Brodin L, Pieribone VA, Greengard P, Shupliakov O. Colocalization of synapsin and actin during synaptic vesicle recycling. Journal Of Cell Biology 2003, 161: 737-747. PMID: 12756235, PMCID: PMC2199372, DOI: 10.1083/jcb.200212140.Peer-Reviewed Original ResearchConceptsSynaptic activityEndocytic zonesSynaptic vesicle recyclingSynaptic vesicle clustersMature nerve terminalsPool of vesiclesNerve terminalsActive synapsesGiant synapseVesicle recyclingAvailability of vesiclesSynapsin immunoreactivitySynaptic vesiclesVesicle clustersProminent reductionSynapsinSynapses
2002
Impaired recycling of synaptic vesicles after acute perturbation of the presynaptic actin cytoskeleton
Shupliakov O, Bloom O, Gustafsson JS, Kjaerulff O, Löw P, Tomilin N, Pieribone VA, Greengard P, Brodin L. Impaired recycling of synaptic vesicles after acute perturbation of the presynaptic actin cytoskeleton. Proceedings Of The National Academy Of Sciences Of The United States Of America 2002, 99: 14476-14481. PMID: 12381791, PMCID: PMC137908, DOI: 10.1073/pnas.212381799.Peer-Reviewed Original ResearchConceptsSynaptic vesicle clustersVesicle clustersSynaptic vesiclesEndocytic zonesC2 toxinClostridium botulinum C2 toxinClathrin-coated pitsSynaptic vesicle cycleSynaptic vesicle recyclingAccumulation of aggregatesRole of actinLamprey reticulospinal synapseBotulinum C2 toxinActin functionVesicle transportActin cytoskeletonCatalytic subunitVesicle cycleVesicle recyclingPlasma membraneActin filamentsImpaired recyclingReversible anchoringRecycled vesiclesS1 fragment