2014
Pygo2 regulates β-catenin–induced activation of hair follicle stem/progenitor cells and skin hyperplasia
Sun P, Watanabe K, Fallahi M, Lee B, Afetian ME, Rheaume C, Wu D, Horsley V, Dai X. Pygo2 regulates β-catenin–induced activation of hair follicle stem/progenitor cells and skin hyperplasia. Proceedings Of The National Academy Of Sciences Of The United States Of America 2014, 111: 10215-10220. PMID: 24982158, PMCID: PMC4104891, DOI: 10.1073/pnas.1311395111.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsHair FollicleHyperplasiaIntracellular Signaling Peptides and ProteinsLIM-Homeodomain ProteinsMiceMice, KnockoutStem CellsTranscription FactorsTumor Suppressor Protein p53Wnt Signaling PathwayConceptsStem cell activationStem/progenitor cellsEarly progenitor cellsProgenitor cellsWnt/β-catenin targetsΒ-catenin functionStem cellsTumor suppressor protein p53Β-catenin targetsWnt/β-catenin functionsCell cycle entryAdult stem cellsHair follicle stem cellsSuppressor protein p53Chromatin factorsFollicle stem cellsProgenitor cell compartmentHomeobox proteinEpigenetic mechanismsCell activationCycle entryDownstream eventsPathway functionOrgan regenerationImportant regulator
2009
Epigenetics, Wnt signaling, and stem cells: the Pygo2 connection
Horsley V. Epigenetics, Wnt signaling, and stem cells: the Pygo2 connection. Journal Of Cell Biology 2009, 185: 761-763. PMID: 19487452, PMCID: PMC2711585, DOI: 10.1083/jcb.200904125.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell ProliferationEpigenesis, GeneticGene Expression Regulation, DevelopmentalIntracellular Signaling Peptides and ProteinsMammalsMammary Glands, AnimalModels, BiologicalSignal TransductionStem CellsWnt Proteins