Large-Scale Proteomics in Early Pregnancy and Hypertensive Disorders of Pregnancy
Greenland P, Segal M, McNeil R, Parker C, Pemberton V, Grobman W, Silver R, Simhan H, Saade G, Ganz P, Mehta P, Catov J, Merz C, Varagic J, Khan S, Parry S, Reddy U, Mercer B, Wapner R, Haas D. Large-Scale Proteomics in Early Pregnancy and Hypertensive Disorders of Pregnancy. JAMA Cardiology 2024, 9: 791-799. PMID: 38958943, PMCID: PMC11223045, DOI: 10.1001/jamacardio.2024.1621.Peer-Reviewed Original ResearchArea under the receiver operating characteristic curveCase-control studyHypertensive disordersEarly pregnancyClinical dataSmall-for-gestational-age infantsPrediction of hypertensive disordersSmall-for-gestational-ageHypertensive disorders of pregnancyPrediction of HDPDisorders of pregnancyNested case-control studyPlasma samplesMulticenter observational studyStored plasma samplesReceiver operating characteristic curveBody mass indexGestational hypertensionNon-Hispanic blacksPreterm birthFetal sexFirst-trimesterNon-Hispanic whitesPregnancy outcomesMaternal raceDesign, rationale and protocol for Glycemic Observation and Metabolic Outcomes in Mothers and Offspring (GO MOMs): an observational cohort study
Group T, Scholtens D, LeBlanc E, Vesco K, Amy D, Bays K, Massimino S, Robinson S, Schell K, Walters G, Hillier T, Oshiro C, Cordero S, Howick C, Kim L, Martinez Y, Pishchalenko O, Wastlova V, Zork N, Mourad M, Lonier J, Reddy U, Acevedo J, Castillo J, Gomez M, Peguero B, Facco F, Feghali M, Bocan H, Stramowski S, Powe C, Edlow A, Barth W, Nathan D, Azevedo R, Baez A, Iroajanma C, Larkin M, Maya J, Michalopoulos C, Neamonitaki N, Thangthaeng N, Yee L, Lowe W, Grobman W, Szmuilowicz E, Aguirre A, Guevara E, Mallett G, Matos S, Tyagi S, Spadola A, Catalano P, Azimirad A, Werner E, Rouse D, Malloy M, Parra F, Sherr J, Merriam A, Bitterman S, Considine E, Leventhal J, Perley L, Rink L, Steffen A, Thompson B, Zgorski M, Steffes M, Arends V, Killeen A, Siddique J, Bustamante P, Cheung Y, Freeze C, Grott T, Kuang A, Tull M, Linder B. Design, rationale and protocol for Glycemic Observation and Metabolic Outcomes in Mothers and Offspring (GO MOMs): an observational cohort study. BMJ Open 2024, 14: e084216. PMID: 38851233, PMCID: PMC11163666, DOI: 10.1136/bmjopen-2024-084216.Peer-Reviewed Original ResearchConceptsLarge-for-gestational-age birth weightMetabolic outcomesLarge-for-gestational-ageDiagnosis of gestational diabetesOral glucose tolerance testAdverse pregnancy outcomesVanderbilt University Institutional Review BoardCourse of pregnancyObservational cohort studyGlucose tolerance testNational Institute of DiabetesDigestive and Kidney DiseasesGDM treatmentWeeks gestationDetect such abnormalitiesPerinatal outcomesGDM screeningInstitutional review boardGestational diabetesFirst-trimesterPregnancy outcomesEarly pregnancyGlucose abnormalitiesBirth weightPregnant adults