2023
Comparing population-based fetal growth standards in a US cohort
Gleason J, Reddy U, Chen Z, Grobman W, Wapner R, Steller J, Simhan H, Scifres C, Blue N, Parry S, Grantz K. Comparing population-based fetal growth standards in a US cohort. American Journal Of Obstetrics And Gynecology 2023, 231: 338.e1-338.e18. PMID: 38151220, PMCID: PMC11196385, DOI: 10.1016/j.ajog.2023.12.034.Peer-Reviewed Original ResearchComposite perinatal morbidityFetal growth standardsPerinatal morbidityNeonatal morbidityWorld Health OrganizationGrowth standardsEunice Kennedy Shriver National InstituteNulliparous Pregnancy Outcomes StudyHighest AUCComposite neonatal morbiditySubsequent neonatal morbidityU.S. clinical centersFetal growth restrictionRisk of morbidityRace/Management of pregnancyPregnancy Outcomes StudyAntenatal monitoringNulliparous womenFetal weightFirst trimesterVisit 2Visit 3US cohortClinical centersResearching COVID to enhance recovery (RECOVER) pregnancy study: Rationale, objectives and design
Metz T, Clifton R, Gallagher R, Gross R, Horwitz L, Jacoby V, Martin-Herz S, Peralta-Carcelen M, Reeder H, Beamon C, Chan J, Chang A, Costantine M, Fitzgerald M, Foulkes A, Gibson K, Güthe N, Habli M, Hackney D, Hoffman M, Hoffman M, Hughes B, Katz S, Laleau V, Mallett G, Mendez-Figueroa H, Monzon V, Palatnik A, Palomares K, Parry S, Pettker C, Plunkett B, Poppas A, Reddy U, Rouse D, Saade G, Sandoval G, Schlater S, Sciurba F, Simhan H, Skupski D, Sowles A, Thaweethai T, Thomas G, Thorp J, Tita A, Weiner S, Weigand S, Yee L, Flaherman V, Initiative O. Researching COVID to enhance recovery (RECOVER) pregnancy study: Rationale, objectives and design. PLOS ONE 2023, 18: e0285351. PMID: 38128008, PMCID: PMC10734909, DOI: 10.1371/journal.pone.0285351.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infectionSARS-CoV-2Long-term outcomesMonths of agePregnancy cohortMaternal-Fetal Medicine Units NetworkHealth outcomesSARS-CoV-2 antibody testingAdverse long-term outcomesEunice Kennedy Shriver National InstitutePost-acute sequelaeLong-term sequelaeClinical trial registrationMaternal-child dyadsNational InstituteMulti-site observational studyCalifornia San FranciscoUnique physiologic changesPregnancy modifiesMaternal infectionMultiple gestationsOverall cohortRetrospective cohortAntibody testingLong COVIDDesirability of outcome ranking for obstetrical trials: illustration and application to the ARRIVE trial
SANDOVAL G, GROBMAN W, EVANS S, RICE M, CLIFTON R, CHAUHAN S, COSTANTINE M, GIBSON K, LONGO M, METZ T, MILLER E, PARRY S, REDDY U, ROUSE D, SIMHAN H, THORP J, TITA A, SAADE G, Network E. Desirability of outcome ranking for obstetrical trials: illustration and application to the ARRIVE trial. American Journal Of Obstetrics And Gynecology 2023, 230: 370.e1-370.e12. PMID: 37741532, PMCID: PMC10939984, DOI: 10.1016/j.ajog.2023.09.016.Peer-Reviewed Original ResearchElective inductionARRIVE trialCesarean deliverySecondary outcomesPrimary outcomeVaginal deliveryDesirability of outcomeEunice Kennedy Shriver National InstituteSpontaneous vaginal deliverySevere neonatal complicationsWeeks of gestationOperative vaginal deliveryBetter overall outcomesPerson-centred careNeonatal complicationsObstetric trialsExpectant managementPerinatal deathRandomized trialsDecreased riskPoor outcomeClinical trialsChild healthTreatment scoresOutcome rankingsRisk Factors for Perinatal Transmission of Hepatitis C Virus
Prasad M, Saade G, Clifton R, Sandoval G, Hughes B, Reddy U, Bartholomew A, Salazar A, Chien E, Tita A, Thorp J, Metz T, Wapner R, Sabharwal V, Simhan H, Swamy G, Heyborne K, Sibai B, Grobman W, El-Sayed Y, Casey B, Parry S, Rathore M, Diaz-Velasco R, Puga A, Wiznia A, Kovacs A, Garry D, Macones G. Risk Factors for Perinatal Transmission of Hepatitis C Virus. Obstetrics And Gynecology 2023, 142: 449-456. PMID: 37590978, PMCID: PMC10437102, DOI: 10.1097/aog.0000000000005306.Peer-Reviewed Original ResearchConceptsPerinatal transmissionHCV infectionRisk factorsPrimary outcomeHuman Development Maternal-Fetal Medicine Units NetworkMaternal-Fetal Medicine Units NetworkHepatitis C virus infectionEunice Kennedy Shriver National InstituteC virus infectionPerinatal transmission rateWeeks of gestationHigh viral loadHepatitis C virusMonths of lifePositive test resultsAntepartum bleedingViremic participantsVaginal bleedingHCV RNAViremic individualsViral loadC virusObservational studyVirus infectionDemonstrable viremia
2017
Opioid Use in Pregnancy, Neonatal Abstinence Syndrome, and Childhood Outcomes
Reddy U, Davis J, Ren Z, Greene M. Opioid Use in Pregnancy, Neonatal Abstinence Syndrome, and Childhood Outcomes. Obstetrical & Gynecological Survey 2017, 72: 703-705. DOI: 10.1097/ogx.0000000000000517.Peer-Reviewed Original ResearchNeonatal abstinence syndromeOpioid useAbstinence syndromeChildhood outcomesEunice Kennedy Shriver National InstituteOpioid use disorderMaternal-fetal medicineMarch of DimesAffected womenAmerican CollegeChild healthUse disordersAmerican AcademyDisease controlPregnancyNational InstituteSyndromeOutcomesGynecologistsObstetriciansPediatricsPreventionWomen
2016
Antenatal Betamethasone for Women at Risk for Late Preterm Delivery
Gyamfi-Bannerman C, Thom E, Blackwell S, Tita A, Reddy U, Saade G, Rouse D, McKenna D, Clark E, Thorp J, Chien E, Peaceman A, Gibbs R, Swamy G, Norton M, Casey B, Caritis S, Tolosa J, Sorokin Y, VanDorsten J, Jain L. Antenatal Betamethasone for Women at Risk for Late Preterm Delivery. Obstetrical & Gynecological Survey 2016, 71: 453-455. DOI: 10.1097/01.ogx.0000489576.69844.54.Peer-Reviewed Original ResearchLate preterm periodPreterm periodMaternal-Fetal Medicine Units NetworkEunice Kennedy Shriver National InstituteLate preterm deliveryAdministration of betamethasoneAntenatal betamethasoneNeonatal morbidityPreterm deliveryMulticenter trialClinical centersChildhood complicationsChild healthNational InstituteBetamethasoneWomenRiskMorbidityComplicationsNewbornsInfantsAdministrationTrials
2015
The association of beta‐2 adrenoceptor genotype with short‐cervix mediated preterm birth: a case–control study
Miller R, Smiley R, Thom E, Grobman W, Iams J, Mercer B, Saade G, Tita A, Reddy U, Rouse D, Sorokin Y, Blackwell S, Esplin, Tolosa J, Caritis, Network E. The association of beta‐2 adrenoceptor genotype with short‐cervix mediated preterm birth: a case–control study. BJOG An International Journal Of Obstetrics & Gynaecology 2015, 122: 1387-1394. PMID: 25600430, PMCID: PMC4508241, DOI: 10.1111/1471-0528.13243.Peer-Reviewed Original ResearchConceptsShort cervixCervical lengthAR genotypeMaternal-Fetal Medicine Units NetworkEunice Kennedy Shriver National InstituteNormal cervical lengthShort cervical lengthShort cervix groupPreterm birth riskCase-control studyRace/ethnicitySpontaneous PTBNulliparous womenPregnancy outcomesPreterm birthTransvaginal sonogramsPrimary outcomePTB riskSecond trimesterAncillary studiesChild healthBirth riskCervixAdrenoceptor genotypeControl group
2011
The Stillbirth Collaborative Research Network Postmortem Examination Protocol
Pinar H, Koch M, Hawkins H, Heim-Hall J, Abramowsky C, Thorsten V, Carpenter M, Zhou H, Reddy U. The Stillbirth Collaborative Research Network Postmortem Examination Protocol. American Journal Of Perinatology 2011, 29: 187-202. PMID: 21815127, PMCID: PMC4320124, DOI: 10.1055/s-0031-1284228.Peer-Reviewed Original ResearchConceptsPostmortem examinationStillborn infantsEunice Kennedy Shriver National InstitutePerinatal postmortem examinationCauses of stillbirthTertiary care centerPopulation-based studyCare centerPerinatal pathologistsMedical CenterChild healthStillbirthExamination protocolNational InstituteStandardized approachInfantsResearch NetworkWomenTotalPM protocolPathogenesisCliniciansNICHDCenterNovel testing
2008
Prenatal Imaging
Reddy UM, Filly RA, Copel JA. Prenatal Imaging. Obstetrics And Gynecology 2008, 112: 145-157. PMID: 18591320, PMCID: PMC2788813, DOI: 10.1097/01.aog.0000318871.95090.d9.Peer-Reviewed Original ResearchConceptsFetal magnetic resonance imagingMagnetic resonance imagingNervous system anomaliesFetal central nervous system anomaliesEunice Kennedy Shriver National InstituteCentral nervous system anomaliesNon-central nervous system anomaliesSystem anomaliesFirst-trimester ultrasonographyPrediction of prognosisModality of choiceThree-dimensional ultrasonographyAnatomic surveySpecialized centersFetal sedationFetal observationsChild healthPregnancy evaluationPrenatal imagingUltrasonographyResonance imagingAvailable evidenceRemote reviewNational InstituteClinical application