2011
DOPAMINE MODULATES FLOW‐DEPENDENT TRANSPORT BY NHE3, BUT NOT H+‐ATPASE, IN MOUSE PROXIMAL TUBULES
Du Z, Gotoh N, Weinbaum S, Weinstein A, Wang T. DOPAMINE MODULATES FLOW‐DEPENDENT TRANSPORT BY NHE3, BUT NOT H+‐ATPASE, IN MOUSE PROXIMAL TUBULES. The FASEB Journal 2011, 25: 1041.18-1041.18. DOI: 10.1096/fasebj.25.1_supplement.1041.18.Peer-Reviewed Original ResearchEffects of DAProtein kinase A inhibitor H89Proximal tubules in vitroPKA-mediated mechanismProximal tubule transportReabsorption of fluidTubules in vitroHCO3- absorptionLuminal perfusion rateTubule transportJHCO3Cl- transportProximal tubulesNHE3Perfusion rateDopamineSCH23390JNaPresence of DAInhibitory effectSignaling mechanismsH+-ATPaseDA1No effectFlow-dependent transport
2007
Flow-dependent transport in a mathematical model of rat proximal tubule
Weinstein A, Weinbaum S, Duan Y, Du Z, Yan Q, Wang T. Flow-dependent transport in a mathematical model of rat proximal tubule. American Journal Of Physiology. Renal Physiology 2007, 292: f1164-f1181. PMID: 17213461, DOI: 10.1152/ajprenal.00392.2006.Peer-Reviewed Original ResearchConceptsNa(+) reabsorptionRat proximal tubulesProximal tubulesModel tubuleDiuretic effectMouse proximal tubuleLuminal perfusion rateLow flowsSolute transportNaCl reabsorptionPeritubular transportTranscellular NaCl reabsorptionCarbonic anhydrase inhibitionGlomerulotubular balanceTubulesReabsorptionTransporter densityLuminal flowModel calculationsRatsFlow-dependent transportTransporter insertionMathematical modelPerfusion rateRate of hydrationFlow‐dependent transport in a mathematical model of rat proximal tubule
Weinstein A, Weinbaum S, Duan Y, Du Z, Yan Q, Wang T. Flow‐dependent transport in a mathematical model of rat proximal tubule. The FASEB Journal 2007, 21: a827-a828. DOI: 10.1096/fasebj.21.6.a827-d.Peer-Reviewed Original ResearchRat proximal tubulesNa+ reabsorptionProximal tubulesDiuretic effectModel tubuleOsmotic diuretic effectLow flowsSolute transportMouse tubulesLuminal perfusion rateNaCl reabsorptionPeritubular transportTranscellular NaCl reabsorptionCarbonic anhydrase inhibitionGlomerulotubular balanceTubulesReabsorptionTransporter densityLuminal flowMathematical modelRate of hydrationFlow-dependent transportInlet flowTransportTorque calculation