2024
Life's Essential 8 and Poor Brain Health Outcomes in Middle-Aged Adults
Clocchiatti-Tuozzo S, Rivier C, Renedo D, Huo S, Hawkes M, de Havenon A, Schwamm L, Sheth K, Gill T, Falcone G. Life's Essential 8 and Poor Brain Health Outcomes in Middle-Aged Adults. Neurology 2024, 103: e209990. PMID: 39442069, PMCID: PMC11498939, DOI: 10.1212/wnl.0000000000209990.Peer-Reviewed Original ResearchConceptsLife's Essential 8Poor cardiovascular healthCardiovascular healthBrain healthLife's Essential 8 scoreUnadjusted riskEssential 8Determinants of cardiovascular healthUK Biobank (UKBCardiovascular health profileModifiable cardiovascular risk factorsBrain health outcomesRisk factorsComposite outcomePublic health constructsPopulation studiesMiddle-aged adultsCox modelLate-life depressionCox proportional hazards modelsBrain health benefitsMultivariate Cox modelCardiovascular risk factorsFollow-up timeAoU participants
2016
Restricting Symptoms Before and After Admission to Hospice
Cheraghlou S, Gahbauer EA, Leo-Summers L, Stabenau HF, Chaudhry SI, Gill TM. Restricting Symptoms Before and After Admission to Hospice. The American Journal Of Medicine 2016, 129: 754.e7-754.e15. PMID: 26968471, PMCID: PMC4914433, DOI: 10.1016/j.amjmed.2016.02.017.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAgedAged, 80 and overChest PainCognitive DysfunctionCohort StudiesDepressionDiarrheaDizzinessDyspneaEdemaFatigueFemaleHospice CareHospicesHumansIndependent LivingLongitudinal StudiesMaleMemory DisordersMuscle WeaknessMusculoskeletal PainNauseaPatient AdmissionPrevalenceProspective StudiesSleep Wake DisordersUnited StatesUrologic DiseasesVision DisordersVomitingConceptsHospice admissionEnd of lifeDistressing symptomsMean numberCommunity-dwelling older personsMonthly telephone interviewsOngoing cohort studyMonths of lifeEffect of hospiceHospice treatmentAdmission diagnosisEarly referralMedian durationCohort studySymptom prevalenceSuch symptomsSymptom increasesAdmissionPsychological symptomsSymptomsOlder personsRestricted activityHospiceTelephone interviewsPrevalenceEffects of Testosterone Treatment in Older Men
Snyder PJ, Bhasin S, Cunningham GR, Matsumoto AM, Stephens-Shields AJ, Cauley JA, Gill TM, Barrett-Connor E, Swerdloff RS, Wang C, Ensrud KE, Lewis CE, Farrar JT, Cella D, Rosen RC, Pahor M, Crandall JP, Molitch ME, Cifelli D, Dougar D, Fluharty L, Resnick SM, Storer TW, Anton S, Basaria S, Diem SJ, Hou X, Mohler ER, Parsons JK, Wenger NK, Zeldow B, Landis JR, Ellenberg SS. Effects of Testosterone Treatment in Older Men. New England Journal Of Medicine 2016, 374: 611-624. PMID: 26886521, PMCID: PMC5209754, DOI: 10.1056/nejmoa1506119.Peer-Reviewed Original ResearchConceptsMid-normal rangeMen 65 yearsSerum testosterone concentrationsYears of ageTestosterone treatmentTestosterone levelsTestosterone concentrationsMen 19Depressive symptomsOlder menChronic Illness Therapy-Fatigue ScalePsychosexual Daily QuestionnaireSerum testosterone levelsPercentage of menAdverse eventsErectile functionPrimary outcomePlacebo gelSexual functionStudy groupWalking distanceFunctional assessmentMen ageModerate benefitDaily questionnaires
2000
Dizziness among older adults: a possible geriatric syndrome.
Tinetti M, Williams C, Gill T. Dizziness among older adults: a possible geriatric syndrome. Annals Of Internal Medicine 2000, 132: 337-44. PMID: 10691583, DOI: 10.7326/0003-4819-132-5-200003070-00002.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnxietyConnecticutCross-Sectional StudiesDepressionDizzinessDrug-Related Side Effects and Adverse ReactionsFemaleHearing DisordersHumansHypotension, OrthostaticMaleMyocardial InfarctionPostural BalancePrevalenceRisk FactorsSensation DisordersStatistics as TopicSyndromeConceptsAdjusted relative riskGeriatric syndromesRelative riskEpisodes of dizzinessCommunity-living personsPast myocardial infarctionCross-sectional studyYears of agePostural hypotensionMore medicationsMyocardial infarctionImpaired balanceDizzinessDepressive symptomsSyndromeImpaired hearingSpecific causesOlder adultsMultiple causesSymptomsProbability sampleRiskSensationCauseNew Haven