2023
Pragmatic evaluation of events and benefits of lipid lowering in older adults (PREVENTABLE): Trial design and rationale
Joseph J, Pajewski N, Dolor R, Sellers M, Perdue L, Peeples S, Henrie A, Woolard N, Jones W, Benziger C, Orkaby A, Mixon A, VanWormer J, Shapiro M, Kistler C, Polonsky T, Chatterjee R, Chamberlain A, Forman D, Knowlton K, Gill T, Newby L, Hammill B, Cicek M, Williams N, Decker J, Ou J, Rubinstein J, Choudhary G, Gazmuri R, Schmader K, Roumie C, Vaughan C, Effron M, Cooper‐DeHoff R, Supiano M, Shah R, Whittle J, Hernandez A, Ambrosius W, Williamson J, Alexander K, Group P. Pragmatic evaluation of events and benefits of lipid lowering in older adults (PREVENTABLE): Trial design and rationale. Journal Of The American Geriatrics Society 2023, 71: 1701-1713. PMID: 37082807, PMCID: PMC10258159, DOI: 10.1111/jgs.18312.Peer-Reviewed Original ResearchConceptsOlder adultsHigh-intensity statin therapyRandomized pragmatic clinical trialCognitive testingBenefits of lipidInitiation of statinsBenefits of statinsNational Death Index searchEffect of statinsPragmatic clinical trialsCommunity-dwelling adultsMild cognitive impairmentLow participant burdenBaseline cognitive testingElectronic health recordsCardiovascular deathCardiovascular eventsCoronary revascularizationLipid panelStatin therapyStatin useUnstable anginaHeart failurePrimary outcomeMyocardial infarction
2000
Dizziness among older adults: a possible geriatric syndrome.
Tinetti M, Williams C, Gill T. Dizziness among older adults: a possible geriatric syndrome. Annals Of Internal Medicine 2000, 132: 337-44. PMID: 10691583, DOI: 10.7326/0003-4819-132-5-200003070-00002.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnxietyConnecticutCross-Sectional StudiesDepressionDizzinessDrug-Related Side Effects and Adverse ReactionsFemaleHearing DisordersHumansHypotension, OrthostaticMaleMyocardial InfarctionPostural BalancePrevalenceRisk FactorsSensation DisordersStatistics as TopicSyndromeConceptsAdjusted relative riskGeriatric syndromesRelative riskEpisodes of dizzinessCommunity-living personsPast myocardial infarctionCross-sectional studyYears of agePostural hypotensionMore medicationsMyocardial infarctionImpaired balanceDizzinessDepressive symptomsSyndromeImpaired hearingSpecific causesOlder adultsMultiple causesSymptomsProbability sampleRiskSensationCauseNew Haven