2022
Giving up on the objective of providing goal‐concordant care: Advance care planning for improving caregiver outcomes
Fried TR. Giving up on the objective of providing goal‐concordant care: Advance care planning for improving caregiver outcomes. Journal Of The American Geriatrics Society 2022, 70: 3006-3011. PMID: 35974460, PMCID: PMC9588724, DOI: 10.1111/jgs.18000.Peer-Reviewed Original ResearchConceptsAdvance care planningGoal-concordant careCaregiver outcomesCare planningAdvance directivesPost-traumatic stress disorderEnd of lifeAdverse outcomesPatient goalsPatient Self-Determination ActElevated riskPatient's life storyAppropriate careSelf-Determination ActStress disorderCareCaregiversHealthcare agentsOutcomesPatientsFacilitation of communicationPrimary objectiveCritical determinantClinicians
2019
Medication Appropriateness in Vulnerable Older Adults: Healthy Skepticism of Appropriate Polypharmacy
Fried TR, Mecca MC. Medication Appropriateness in Vulnerable Older Adults: Healthy Skepticism of Appropriate Polypharmacy. Journal Of The American Geriatrics Society 2019, 67: 1123-1127. PMID: 30697698, PMCID: PMC6561813, DOI: 10.1111/jgs.15798.Peer-Reviewed Original ResearchConceptsNumber of medicationsAppropriate polypharmacyOlder adultsMedication benefitsComplex medication regimensMultiple chronic conditionsVulnerable older adultsMedication appropriatenessUnderestimate harmsInappropriate medicationsMore medicationsAdverse eventsMore observational studiesMedication regimensComplex regimenAdverse outcomesAppropriate medicationChronic conditionsMedications resultsObservational studyPolypharmacyMedicationsHealth outcomesCorrect medicationLikelihood of harm
2002
Understanding the Treatment Preferences of Seriously Ill Patients
Fried TR, Bradley EH, Towle VR, Allore H. Understanding the Treatment Preferences of Seriously Ill Patients. New England Journal Of Medicine 2002, 346: 1061-1066. PMID: 11932474, DOI: 10.1056/nejmsa012528.Peer-Reviewed Original ResearchConceptsBurden of treatmentTreatment preferencesAdverse outcomesCognitive impairmentChronic obstructive pulmonary diseaseLow-burden treatmentCongestive heart failureObstructive pulmonary diseaseSevere functional impairmentLimited life expectancyOutcome of treatmentAdvance care planningYears of agePercent of participantsLife-sustaining treatmentHeart failureIll patientsPulmonary diseaseQuestions patientsPatient preferencesPrimary diagnosisPatients' attitudesFunctional impairmentHigh burdenCare planning