2016
The Contributions of the Ribosome Biogenesis Protein Utp5/WDR43 to Craniofacial Development
Sondalle SB, Baserga SJ, Yelick PC. The Contributions of the Ribosome Biogenesis Protein Utp5/WDR43 to Craniofacial Development. Journal Of Dental Research 2016, 95: 1214-1220. PMID: 27221611, PMCID: PMC5076753, DOI: 10.1177/0022034516651077.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsRibosomal proteinsCraniofacial developmentRibosome biogenesis proteinsRibosomal protein functionHuman craniofacial developmentTissue-specific defectsDiverse cell typesHuman ribosomopathiesBiogenesis proteinsTranslational machineryProtein functionDistinct functionsTranslational mechanismsTissue differentiationCell typesWDR43Global defectsProteinExciting researchSurprising similaritiesUnderstanding of rolesRibosomopathiesBiogenesisMachineryMutations
2013
The novel zebrafish mutant fantome/wdr43 as a human craniofacial ribosomopathy model
LaBonty M, Zhao C, McCann K, Andreeva V, Baserga S, Yelick P. The novel zebrafish mutant fantome/wdr43 as a human craniofacial ribosomopathy model. The FASEB Journal 2013, 27: 319.1-319.1. DOI: 10.1096/fasebj.27.1_supplement.319.1.Peer-Reviewed Original ResearchMRNA injectionNeural crest cell populationsCrest cell populationsSubcellular localization studiesQRT-PCRStable cell linesWISH analysesNorthern blot analysisPremature stop codonMutant exhibitsRRNA biogenesisRibosomal proteinsFan mutantsPositional cloningHuman neurocristopathiesAntisense morpholino oligomersCraniofacial developmentSubcellular localizationFan alleleNucleolar phosphoproteinWDR43Stop codonP53 signalingLocalization studiesBlot analysis