2023
Peripheral signature of altered synaptic integrity in young onset cannabis use disorder: A proteomic study of circulating extracellular vesicles
Ganesh S, Lam T, Garcia-Milian R, D'Souza D, Nairn A, Elgert K, Eitan E, Ranganathan M. Peripheral signature of altered synaptic integrity in young onset cannabis use disorder: A proteomic study of circulating extracellular vesicles. The World Journal Of Biological Psychiatry 2023, 24: 603-613. PMID: 36994633, PMCID: PMC10471733, DOI: 10.1080/15622975.2023.2197039.Peer-Reviewed Original ResearchConceptsNeuron-derived extracellular vesiclesLabel-free quantification mass spectrometryProteomic studiesCannabis use disorderExtracellular vesiclesMass spectrometry proteomic analysisDifferential proteomic profilesAdapter proteinProteomic analysisPost-synaptic densityPeripheral signatureMolecular basisProteomic profilesProteinMarkers of neuropathologyBrain tissue samplesSynaptic pathologyVesiclesSynaptic integrityImmunoaffinity methodUse disordersFunctional integrityImportant insightsNeuropathologyPilot study
2017
Adult Attention Deficit Hyperactivity Disorder in Patients with Substance Use Disorders: A Study from Southern India
Ganesh S, Kandasamy A, Sahayaraj U, Benegal V. Adult Attention Deficit Hyperactivity Disorder in Patients with Substance Use Disorders: A Study from Southern India. Indian Journal Of Psychological Medicine 2017, 39: 59-62. PMID: 28250560, PMCID: PMC5329993, DOI: 10.4103/0253-7176.198945.Peer-Reviewed Original ResearchAttention deficit hyperactivity disorderSubstance use disordersPrevalence of ADHDDeficit hyperactivity disorderTreatment-seeking patientsHyperactivity disorderAdult ADHD Self-Report Scale (ASRS-v1.1) Symptom ChecklistAdult attention deficit hyperactivity disorderOppositional defiant disorderUse disordersDisorders of childhoodInattention domainADHD scoresDefiant disorderConduct disorderDevelopmental disordersSymptom ChecklistSUD patientsLater leadIndependent samplesLarge sampleEarly onsetLate-onset subtypesDependent groupEarly-onset group