2018
Childhood trauma moderates inhibitory control and anterior cingulate cortex activation during stress
Zhai ZW, Yip SW, Lacadie CM, Sinha R, Mayes LC, Potenza MN. Childhood trauma moderates inhibitory control and anterior cingulate cortex activation during stress. NeuroImage 2018, 185: 111-118. PMID: 30342975, PMCID: PMC6392043, DOI: 10.1016/j.neuroimage.2018.10.049.Peer-Reviewed Original ResearchConceptsAnterior cingulate cortexStroop errorsInhibitory controlChildhood traumaStress reactivityStroop colour-word task performanceStroop color-word taskAnterior cingulate cortex activationColor-word taskInhibitory control processesRostral cingulate zoneFunctional magnetic resonanceHigh childhood traumaNeural correlatesTask performanceBrain activationSubjective anxietyACC activationAffective responsesCortex activationAddictive behaviorsEarly traumaStress cuesNeurodevelopmental changesCingulate cortex
2017
Altered functional connectivity to stressful stimuli in prenatally cocaine-exposed adolescents
Zakiniaeiz Y, Yip SW, Balodis IM, Lacadie CM, Scheinost D, Constable RT, Mayes LC, Sinha R, Potenza MN. Altered functional connectivity to stressful stimuli in prenatally cocaine-exposed adolescents. Drug And Alcohol Dependence 2017, 180: 129-136. PMID: 28888152, PMCID: PMC5808433, DOI: 10.1016/j.drugalcdep.2017.07.030.Peer-Reviewed Original ResearchConceptsPrenatal cocaine exposureNeutral-relaxing conditionsPCE adolescentsParietal connectivityConnectivity analysisSensory areasAdolescent brain functionFunctional magnetic resonance imagingCue interaction effectsIntrinsic connectivity analysesMedial prefrontal areasSeed-based connectivity analysisSubstance Use InitiationAltered functional connectivityAppetitive cuesObesity vulnerabilityPCE statusNeural responsesCorticolimbic connectivityPrefrontal areasFunctional connectivityCraving scoresUtero drug exposureGroup differencesLess connectivity
2015
Prenatal cocaine exposure, illicit-substance use and stress and craving processes during adolescence
Yip SW, Lacadie CM, Sinha R, Mayes LC, Potenza MN. Prenatal cocaine exposure, illicit-substance use and stress and craving processes during adolescence. Drug And Alcohol Dependence 2015, 158: 76-85. PMID: 26627911, PMCID: PMC4698087, DOI: 10.1016/j.drugalcdep.2015.11.012.Peer-Reviewed Original ResearchConceptsPrenatal cocaine exposureIllicit substance useNeural responsesCocaine exposureFunctional neural responsesFunctional magnetic resonance imaging (fMRI) dataDifferent neural substratesOngoing longitudinal studyThree-way interactionCortical brain regionsCue conditionImagery scriptsPCE statusAdolescent developmentStress processingNeural substratesIllicit substance usersPrefrontal cortexRight insulaMagnetic resonance imaging dataNeural activityUtero cocaine exposureSubjective ratingsCortical activityOpposite pattern
2014
Prenatal Cocaine Exposure and Adolescent Neural Responses to Appetitive and Stressful Stimuli
Yip SW, Potenza EB, Balodis IM, Lacadie CM, Sinha R, Mayes LC, Potenza MN. Prenatal Cocaine Exposure and Adolescent Neural Responses to Appetitive and Stressful Stimuli. Neuropsychopharmacology 2014, 39: 2824-2834. PMID: 24903650, PMCID: PMC4200493, DOI: 10.1038/npp.2014.133.Peer-Reviewed Original ResearchConceptsPrenatal cocaine exposureFavorite-food cuesFunctional magnetic resonance imagingPCE adolescentsPrefrontal cortexVentral striatumNeural responsesBrain regionsAdolescents' neural responsesSubjective food cravingsDorsolateral PFC activationSubjective anxiety ratingsDorsolateral prefrontal cortexCocaine exposureSubcortical brain regionsDevelopment of addictionPFC activationEmotional regulationHuman adolescentsSubstance use disordersAppetitive processingMotivational controlAddiction vulnerabilityHippocampus activityFood cravings