2016
Anticipatory reward processing among cocaine-dependent individuals with and without concurrent methadone-maintenance treatment: Relationship to treatment response
Yip SW, DeVito EE, Kober H, Worhunsky PD, Carroll KM, Potenza MN. Anticipatory reward processing among cocaine-dependent individuals with and without concurrent methadone-maintenance treatment: Relationship to treatment response. Drug And Alcohol Dependence 2016, 166: 134-142. PMID: 27430401, PMCID: PMC5082418, DOI: 10.1016/j.drugalcdep.2016.07.006.Peer-Reviewed Original ResearchConceptsMethadone maintenance treatmentCocaine-dependent individualsBOLD responseCocaine dependenceSignificant public health problemMethadone-maintained individualsMethadone-maintained populationsMethadone-maintained patientsElevated relapse ratesPublic health problemCocaine-negative urinesCocaine-dependent patientsAnticipatory reward processingPosterior cingulate cortexLoss processingDuration of abstinenceDorsolateral prefrontal cortexCD patientsRelapse rateWhole-brain ANOVAInferior frontal gyrusTreatment outcomesRight caudateHealthy comparison participantsPatients
2014
Prenatal Cocaine Exposure and Adolescent Neural Responses to Appetitive and Stressful Stimuli
Yip SW, Potenza EB, Balodis IM, Lacadie CM, Sinha R, Mayes LC, Potenza MN. Prenatal Cocaine Exposure and Adolescent Neural Responses to Appetitive and Stressful Stimuli. Neuropsychopharmacology 2014, 39: 2824-2834. PMID: 24903650, PMCID: PMC4200493, DOI: 10.1038/npp.2014.133.Peer-Reviewed Original ResearchConceptsPrenatal cocaine exposureFavorite-food cuesFunctional magnetic resonance imagingPCE adolescentsPrefrontal cortexVentral striatumNeural responsesBrain regionsAdolescents' neural responsesSubjective food cravingsDorsolateral PFC activationSubjective anxiety ratingsDorsolateral prefrontal cortexCocaine exposureSubcortical brain regionsDevelopment of addictionPFC activationEmotional regulationHuman adolescentsSubstance use disordersAppetitive processingMotivational controlAddiction vulnerabilityHippocampus activityFood cravings