2014
Gender differences in clinical outcomes for cocaine dependence: Randomized clinical trials of behavioral therapy and disulfiram
DeVito EE, Babuscio TA, Nich C, Ball SA, Carroll KM. Gender differences in clinical outcomes for cocaine dependence: Randomized clinical trials of behavioral therapy and disulfiram. Drug And Alcohol Dependence 2014, 145: 156-167. PMID: 25457739, PMCID: PMC4268325, DOI: 10.1016/j.drugalcdep.2014.10.007.Peer-Reviewed Original ResearchConceptsRandomized clinical trialsClinical trialsClinical outcomesTreatment outcomesCocaine dependenceBehavioral therapyBehavioral treatment conditionsPoor treatment outcomesEvidence-based treatmentsGender differencesWidespread clinical implementationPoor outcomePharmacological treatmentMedication conditionAddiction pharmacotherapyCocaine useSecondary analysisBehavioral treatmentClinical implementationWomenCareful assessmentDisulfiramOutcomesTrialsMenToward empirical identification of a clinically meaningful indicator of treatment outcome: Features of candidate indicators and evaluation of sensitivity to treatment effects and relationship to one year follow up cocaine use outcomes
Carroll KM, Kiluk BD, Nich C, DeVito EE, Decker S, LaPaglia D, Duffey D, Babuscio TA, Ball SA. Toward empirical identification of a clinically meaningful indicator of treatment outcome: Features of candidate indicators and evaluation of sensitivity to treatment effects and relationship to one year follow up cocaine use outcomes. Drug And Alcohol Dependence 2014, 137: 3-19. PMID: 24556275, PMCID: PMC4042667, DOI: 10.1016/j.drugalcdep.2014.01.012.Peer-Reviewed Original Research
2012
Efficacy of disulfiram and Twelve Step Facilitation in cocaine-dependent individuals maintained on methadone: A randomized placebo-controlled trial
Carroll KM, Nich C, Shi JM, Eagan D, Ball SA. Efficacy of disulfiram and Twelve Step Facilitation in cocaine-dependent individuals maintained on methadone: A randomized placebo-controlled trial. Drug And Alcohol Dependence 2012, 126: 224-231. PMID: 22695473, PMCID: PMC3461119, DOI: 10.1016/j.drugalcdep.2012.05.019.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DeterrentsAlcohol DrinkingCocaine-Related DisordersCounselingDemographyDiagnostic and Statistical Manual of Mental DisordersDisulfiramDouble-Blind MethodFemaleFollow-Up StudiesHumansMaleMethadoneNarcoticsOpiate Substitution TreatmentPatient ComplianceRegression AnalysisSelf-Help GroupsSocioeconomic FactorsSubstance Abuse DetectionTreatment OutcomeConceptsMethadone maintenance programEfficacy of disulfiramAlcohol use disorderCocaine useStandard counselingUse disordersCommunity-based methadone maintenance programRandomized placebo-controlled trialPlacebo-controlled trialCurrent alcohol use disorderTwelve-step facilitationCocaine-negative urinesLess cocaine useMethadone maintenanceStep FacilitationCocaine-dependent individualsPlaceboBetter outcomesDisulfiram efficacyTreatment approachesFactorial trialDisulfiramMaintenance programRelative efficacyCocaine users
2009
Depressive Symptoms, Drinking Consequences, and Motivation to Change in First Time DWI Offenders
Holt LJ, O'Malley SS, Rounsaville BJ, Ball SA. Depressive Symptoms, Drinking Consequences, and Motivation to Change in First Time DWI Offenders. The American Journal Of Drug And Alcohol Abuse 2009, 35: 117-122. PMID: 19462293, PMCID: PMC3679647, DOI: 10.1080/00952990802585398.Peer-Reviewed Original ResearchConceptsBeck Depression InventoryDepressive symptomsFirst-time DWI offendersPretreatment depressive symptomsUseful screening toolHigh-risk drinkingPsychosocial assessmentSevere symptomatologyDrinking consequencesAlcohol consumptionDepression InventorySymptomsDWI arrestsScreening toolTime pointsDWI offendersIntervention outcomesDrinking-related consequencesSubsequent treatmentDrinking behaviorPsychological disordersInterventionArrestDrinkingCurrent study
2008
Serious Adverse Events in Randomized Psychosocial Treatment Studies: Safety or Arbitrary Edicts?
Petry NM, Roll JM, Rounsaville BJ, Ball SA, Stitzer M, Peirce JM, Blaine J, Kirby KC, McCarty D, Carroll KM. Serious Adverse Events in Randomized Psychosocial Treatment Studies: Safety or Arbitrary Edicts? Journal Of Consulting And Clinical Psychology 2008, 76: 1076-1082. PMID: 19045975, PMCID: PMC2756150, DOI: 10.1037/a0013679.Peer-Reviewed Original ResearchConceptsSerious adverse eventsAdverse eventsStandard careDrug Abuse Clinical Trials NetworkMore (95% CI 4 to 167 more) serious adverse eventsSAE incidence rateClinical Trials NetworkPsychosocial treatment studiesPsychosocial intervention studiesPercent of participantsPsychosocial trialsIncidence ratePharmaceutical trialsTherapy trialsIntervention studiesTreatment studiesTrials NetworkHuman subjects protection policiesSubstance-abusing participantsContingency managementMotivational enhancementNational InstituteTrialsSignificant differencesCareEnduring effects of a computer-assisted training program for cognitive behavioral therapy: A 6-month follow-up of CBT4CBT
Carroll KM, Ball SA, Martino S, Nich C, Babuscio TA, Rounsaville BJ. Enduring effects of a computer-assisted training program for cognitive behavioral therapy: A 6-month follow-up of CBT4CBT. Drug And Alcohol Dependence 2008, 100: 178-181. PMID: 19041197, PMCID: PMC2742309, DOI: 10.1016/j.drugalcdep.2008.09.015.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyBehavioral therapyComputer-assisted training programSubstance dependenceComputer-based trainingSubstance use outcomesComputer-assisted versionDrug useEnduring effectCBT4CBTUse outcomesRandomized clinical trialsTreatment retentionDurability of effectTraining programOutpatient communityStudy treatmentStandard treatmentOutpatient treatmentClinical trialsTreatment conditionsParticipantsSignificant differencesTreatmentRegression analysis
2007
Site Matters: Multisite Randomized Trial of Motivational Enhancement Therapy in Community Drug Abuse Clinics
Ball SA, Martino S, Nich C, Frankforter TL, Van Horn D, Crits-Christoph P, Woody GE, Obert JL, Farentinos C, Carroll KM. Site Matters: Multisite Randomized Trial of Motivational Enhancement Therapy in Community Drug Abuse Clinics. Journal Of Consulting And Clinical Psychology 2007, 75: 556-567. PMID: 17663610, PMCID: PMC2148493, DOI: 10.1037/0022-006x.75.4.556.Peer-Reviewed Original ResearchConceptsMotivational enhancement therapySubstance useEnhancement therapyBrief intervention conditionsOutpatient substance abuse programsSubstance use reductionDrug abuse clinicsSubstance abuse programsSession audiotapesRandomized trialsClinical trialsMultisite Randomized TrialSustained reductionTherapy phaseDrug usersPrimary alcohol usersAlcohol usersAbuse programsIntervention conditionSignificant increaseTherapyTrialsCAUOutpatientsClinicConcurrent and Predictive Validity of Drug Use and Psychiatric Diagnosis Among First‐Time DWI Offenders
Palmer RS, Ball SA, Rounsaville BJ, O'Malley SS. Concurrent and Predictive Validity of Drug Use and Psychiatric Diagnosis Among First‐Time DWI Offenders. Alcohol Clinical And Experimental Research 2007, 31: 619-624. PMID: 17374041, DOI: 10.1111/j.1530-0277.2007.00346.x.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdultAlcohol DrinkingAlcoholic IntoxicationAnxiety DisordersAutomobile DrivingCrimeData Interpretation, StatisticalFemaleFollow-Up StudiesHumansInterview, PsychologicalMaleMental DisordersMood DisordersPredictive Value of TestsPrognosisPsychiatric Status Rating ScalesReproducibility of ResultsSubstance-Related DisordersConceptsDWI offendersMore alcohol-related negative consequencesAlcohol-related negative consequencesFirst-time DWI offendersNegative consequencesGreater readinessLifetime diagnosisGroup counseling interventionPsychiatric diagnosisIntervention terminationPredictive validitySubstance dependenceCounseling interventionOffendersCurrent studyDrug abuseMood disordersIntoxicated offendersPsychiatric disordersProgram admissionDrug useDrinkingInterventionAlcohol consumptionReadiness
2005
Motivational interviewing to improve treatment engagement and outcome in individuals seeking treatment for substance abuse: A multisite effectiveness study
Carroll KM, Ball SA, Nich C, Martino S, Frankforter TL, Farentinos C, Kunkel LE, Mikulich-Gilbertson SK, Morgenstern J, Obert JL, Polcin D, Snead N, Woody GE, Network F. Motivational interviewing to improve treatment engagement and outcome in individuals seeking treatment for substance abuse: A multisite effectiveness study. Drug And Alcohol Dependence 2005, 81: 301-312. PMID: 16169159, PMCID: PMC2386852, DOI: 10.1016/j.drugalcdep.2005.08.002.Peer-Reviewed Original ResearchConceptsClinical practiceCommunity-based treatment settingsCourse of treatmentStandard clinical practiceCommunity-based cliniciansForm of treatmentMultisite effectiveness studyMI techniquesMotivational interviewing techniquesSubstance use outcomesSession audiotapesEvaluation sessionsOutpatient treatmentClinical trialsImproved outcomesStandard interventionTreatment settingsTreatment engagementBehavioral therapyEffectiveness studiesSubstance abuseSame sessionUse outcomesHigher skill ratingsSubstance usersWe Don't Train in Vain: A Dissemination Trial of Three Strategies of Training Clinicians in Cognitive-Behavioral Therapy
Sholomskas DE, Syracuse-Siewert G, Rounsaville BJ, Ball SA, Nuro KF, Carroll KM. We Don't Train in Vain: A Dissemination Trial of Three Strategies of Training Clinicians in Cognitive-Behavioral Therapy. Journal Of Consulting And Clinical Psychology 2005, 73: 106-115. PMID: 15709837, PMCID: PMC2367057, DOI: 10.1037/0022-006x.73.1.106.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapy manualManual-only conditionCognitive behavioral therapyClinician's abilityPrimary outcome measureCommunity-based cliniciansTraining Web siteDifferent training strategiesCBT interventionTraining conditionsTreatment manualTherapy manualSkill ratingsIndependent ratingsImpact of exposureOutcome measuresTraining cliniciansDissemination trialTraining strategyLittle researchStructured rolesDidactic seminarsOnly conditionIntermediate scoresSignificant differences
2000
One‐year follow‐up of disulfiram and psychotherapy for cocaine‐alcohol users: sustained effects of treatment
Carroll K, Nich C, Ball S, McCance E, Frankforter T, Rounsaville B. One‐year follow‐up of disulfiram and psychotherapy for cocaine‐alcohol users: sustained effects of treatment. Addiction 2000, 95: 1335-1349. PMID: 11048353, DOI: 10.1046/j.1360-0443.2000.95913355.x.Peer-Reviewed Original ResearchConceptsCognitive-behavioral treatmentTwelve-step facilitationInitiation of abstinenceAlcohol useSubstance abuse treatment centersFrequency of cocaineAlcohol-dependent individualsClinical managementMain effectBrief treatmentEfficacy of disulfiramUrine toxicology screenCessation of treatmentBreathalyzer testEnd of treatmentOutcomes 1 yearAbstinencePercentage of daysEffect of treatmentCocaineLong-term benefitsToxicology screenTreatment centersBetter outcomesBrief period
1999
Concurrent and Predictive Validity of Antisocial Personality Disorder Subtyping among Substance Abusers
CECERO J, BALL S, TENNEN H, KRANZLER H, ROUNSAVILLE B. Concurrent and Predictive Validity of Antisocial Personality Disorder Subtyping among Substance Abusers. The Journal Of Nervous And Mental Disease 1999, 187: 478-486. PMID: 10463065, DOI: 10.1097/00005053-199908000-00004.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmbulatory CareAntisocial Personality DisorderChi-Square DistributionComorbidityDepressive DisorderDiagnosis, Dual (Psychiatry)Follow-Up StudiesHospitalizationHumansMental DisordersMultivariate AnalysisPersonality InventoryProbabilityPsychiatric Status Rating ScalesPsychometricsReproducibility of ResultsSeverity of Illness IndexSubstance-Related DisordersConceptsAntisocial personality disorderAdult antisocial behaviorLifetime depressionPsychiatric severityFull ASPDSubstance abusersPersonality disorderHistory of depressionAxis II pathologyOutpatient substance abusersPoor prognosisBaseline severityGreater baselineSubstance useSeverityDisordersStrongest predictorDepressionMultivariate regressionSubtypesBaselinePredictive validityAbusersVersusPrognosis