2023
A PILOT STUDY: SPATIOTEMPORALLY-RESOLVED MOLECULAR MECHANISMS OF ACUTE IMMUNE AND NEUROMODULATORY RESPONSES TO TRAUMATIC BRAIN INJURY
Mohammed F, Mcguone D, Omay S, Omay Z, Zhou J. A PILOT STUDY: SPATIOTEMPORALLY-RESOLVED MOLECULAR MECHANISMS OF ACUTE IMMUNE AND NEUROMODULATORY RESPONSES TO TRAUMATIC BRAIN INJURY. IBRO Neuroscience Reports 2023, 15: s189-s190. DOI: 10.1016/j.ibneur.2023.08.289.Peer-Reviewed Original Research
2022
Nanoparticle-based drug delivery for the treatment of traumatic brain injury
Mohammed F, Omay S, Sheth K, Zhou J. Nanoparticle-based drug delivery for the treatment of traumatic brain injury. Expert Opinion On Drug Delivery 2022, 20: 55-73. PMID: 36420918, PMCID: PMC9983310, DOI: 10.1080/17425247.2023.2152001.Peer-Reviewed Original ResearchConceptsTraumatic brain injuryBrain injurySecondary outcomesClinical trialsPathophysiology of TBIPhase III clinical trialsPhase II clinical trialClinical management strategiesSite of injuryOff-target toxicityPharmacological treatmentBrain penetrationLow off-target toxicityExperimental animalsInjuryChronic timescalesDosage thresholdDrug deliveryTrialsDrug targetingOutcomesTreatmentDeliveryPathophysiology
2020
Detecting Seizures and Epileptiform Abnormalities in Acute Brain Injury
Singla S, Garcia GE, Rovenolt GE, Soto AL, Gilmore EJ, Hirsch LJ, Blumenfeld H, Sheth KN, Omay SB, Struck AF, Westover MB, Kim JA. Detecting Seizures and Epileptiform Abnormalities in Acute Brain Injury. Current Neurology And Neuroscience Reports 2020, 20: 42. PMID: 32715371, PMCID: PMC9353690, DOI: 10.1007/s11910-020-01060-4.Peer-Reviewed Original ResearchConceptsIctal-interictal continuumBrain injuryAcute brain injuryBetter clinical outcomesTraumatic brain injuryRecent FindingsCurrent literatureIncreased morbidityClinical outcomesEpileptiform abnormalitiesEEG findingsMortality riskEEG monitoringEpileptiform patternsPrognostic modelSeizuresClinical settingInjuryLogistical barriersElectroencephalogram studyUse of EEGABIPractical barriersEEG analysisEEGMorbidity