2021
In Silico Exploration of the Potential Role of Acetaminophen and Pesticides in the Etiology of Autism Spectrum Disorder
Furnary T, Garcia-Milian R, Liew Z, Whirledge S, Vasiliou V. In Silico Exploration of the Potential Role of Acetaminophen and Pesticides in the Etiology of Autism Spectrum Disorder. Toxics 2021, 9: 97. PMID: 33925648, PMCID: PMC8146009, DOI: 10.3390/toxics9050097.Peer-Reviewed Original ResearchReactive oxygen speciesBiological processesEtiology of ASDCell death processSpecific metabolic pathwaysFunctional annotationInteraction networksCommon genesBiological pathwaysMetabolic pathwaysDatabase miningDeath processGenesGenetic associationOxygen speciesCarbohydrate metabolismNetwork topology analysisPesticide exposurePathwaySilico explorationPotential roleEnvironmental sourcesNeurodevelopmental disordersMetabolismTopology analysis
2019
Transcriptome-wide piRNA profiling in human brains for aging genetic factors.
Mao Q, Fan L, Wang X, Lin X, Cao Y, Zheng C, Zhang Y, Zhang H, Garcia-Milian R, Kang L, Shi J, Yu T, Wang K, Zuo L, Li CR, Guo X, Luo X. Transcriptome-wide piRNA profiling in human brains for aging genetic factors. 2019, 4 PMID: 32149191, PMCID: PMC7059831.Peer-Reviewed Original ResearchPIWI-interacting RNAsTransposable elementsAge-associated genesCritical genetic determinantsGenomic integrityExpression regulationCancer stem cellsMicroarray technologyGenetic determinantsStem cellsExpression levelsRenewal capacityMolecular featuresBiological systemsPotential roleGenetic factorsYears of survivalUnderlying mechanismHuman prefrontal cortexGermlineGenesRNADisease statusMultiple testingPrefrontal cortex