Treatment of Low Bone Density or Osteoporosis to Prevent Fractures in Men and Women: A Clinical Practice Guideline Update From the American College of Physicians.
Qaseem A, Forciea M, McLean R, Denberg T, Barry M, Cooke M, Fitterman N, Harris R, Humphrey L, Kansagara D, McLean R, Mir T, Schünemann H. Treatment of Low Bone Density or Osteoporosis to Prevent Fractures in Men and Women: A Clinical Practice Guideline Update From the American College of Physicians. Annals Of Internal Medicine 2017, 166: 818-839. PMID: 28492856, DOI: 10.7326/m15-1361.Peer-Reviewed Original ResearchConceptsLow bone densityBone densityPharmacologic treatmentVertebral fracturesPatient populationAmerican CollegeSystematic reviewACP Clinical Guidelines CommitteeClinical Practice Guideline UpdateLong-term pharmacologic treatmentBone density monitoringClinical Guidelines CommitteeFracture risk profileWomen 65 yearsMenopausal estrogen therapyCost of medicationsLarge observational studiesTreatment of osteoporosisTarget patient populationProgestogen therapyEstrogen therapyAdverse eventsPharmacologic therapyOsteoporotic womenPhysician recommendationOral Pharmacologic Treatment of Type 2 Diabetes Mellitus: A Clinical Practice Guideline Update From the American College of Physicians.
Qaseem A, Barry M, Humphrey L, Forciea M, Fitterman N, Horwitch C, Kansagara D, McLean R, Wilt T. Oral Pharmacologic Treatment of Type 2 Diabetes Mellitus: A Clinical Practice Guideline Update From the American College of Physicians. Annals Of Internal Medicine 2017, 166: 279-290. PMID: 28055075, DOI: 10.7326/m16-1860.Peer-Reviewed Original ResearchConceptsType 2 diabetesOral pharmacologic treatmentGlycemic controlPharmacologic treatmentPatient populationAmerican CollegeSodium-glucose cotransporter 2 inhibitorsType 2Clinical Practice Guideline UpdateDipeptidyl peptidase-4 inhibitorsCotransporter 2 inhibitorsSGLT-2 inhibitorsSystolic blood pressurePeptidase-4 inhibitorsDPP-4 inhibitorsTarget patient populationTotality of evidenceACP guidelinesCerebrovascular morbidityCause mortalityOral medicationsOral therapyPharmacologic therapyBlood pressureHemoglobin A1c