2022
Patient-Centered Pain Care Using Artificial Intelligence and Mobile Health Tools
Piette JD, Newman S, Krein SL, Marinec N, Chen J, Williams DA, Edmond SN, Driscoll M, LaChappelle KM, Kerns RD, Maly M, Kim HM, Farris KB, Higgins DM, Buta E, Heapy AA. Patient-Centered Pain Care Using Artificial Intelligence and Mobile Health Tools. JAMA Internal Medicine 2022, 182: 975-983. PMID: 35939288, PMCID: PMC9361183, DOI: 10.1001/jamainternmed.2022.3178.Peer-Reviewed Original ResearchMeSH KeywordsArtificial IntelligenceChronic PainCognitive Behavioral TherapyFemaleHumansMaleMiddle AgedPatient-Centered CareTelemedicineTreatment OutcomeConceptsCBT-CPComparative effectiveness trialTherapist timeSecondary outcomesMore patientsEffectiveness trialInteractive voice responseCP groupMeaningful improvementsPatient-centered pain careRoland-Morris Disability QuestionnaireVeterans Affairs Health SystemMorris Disability QuestionnairePain intensity scoresChronic back painLess therapist timeMobile health toolsCognitive behavioral therapyRandomized noninferiorityDisability QuestionnaireNoninferiority criteriaOpioid analgesicsPain intensityPain therapyPrimary outcome
2021
Psychological Interventions for the Treatment of Chronic Pain in Adults
Driscoll MA, Edwards RR, Becker WC, Kaptchuk TJ, Kerns RD. Psychological Interventions for the Treatment of Chronic Pain in Adults. Psychological Science In The Public Interest 2021, 22: 52-95. PMID: 34541967, DOI: 10.1177/15291006211008157.Peer-Reviewed Original ResearchMeSH KeywordsAcceptance and Commitment TherapyAdultChronic PainCognitive Behavioral TherapyHumansMindfulnessPsychosocial InterventionConceptsPsychological interventionsCognitive behavioral therapyChronic painPrimary conceptual frameworkPsychological processesCo-occurring disordersIndividual differencesPsychological treatmentPsychological approachResilience factorsCommitment TherapyExpression therapyBiopsychosocial modelAdditional scientific knowledgeComplex experienceImpact of painMultiple pain conditionsSerious public health concernModel of carePublic health concernInterventionOpioid therapyAdultsPain conditionsMindfulnessIncorporating walking into cognitive behavioral therapy for chronic pain: safety and effectiveness of a personalized walking intervention
Heapy AA, Tankha H, Higgins DM, Driscoll M, LaChappelle KM, Goulet JL, Buta E, Piette JD, Kerns RD, Krein SL. Incorporating walking into cognitive behavioral therapy for chronic pain: safety and effectiveness of a personalized walking intervention. Journal Of Behavioral Medicine 2021, 44: 260-269. PMID: 33386530, DOI: 10.1007/s10865-020-00193-8.Peer-Reviewed Original ResearchConceptsAdverse eventsCognitive behavioral therapyChronic painBehavioral therapyCBT-CPLongstanding painWalking interventionsDaily stepsTreatment groupsPainInteractive voice responseStudy sampleWeekly goalsSignificant differencesSignificant increaseTherapyTreatmentParticipantsVoice responseSafetyPersonsBaselineWeeks
2020
Predictors of engagement in an internet-based cognitive behavioral therapy program for veterans with chronic low back pain
Solar C, Halat AM, MacLean RR, Rajeevan H, Williams DA, Krein SL, Heapy AA, Bair MJ, Kerns RD, Higgins DM. Predictors of engagement in an internet-based cognitive behavioral therapy program for veterans with chronic low back pain. Translational Behavioral Medicine 2020, 11: 1274-1282. PMID: 33098304, DOI: 10.1093/tbm/ibaa098.Peer-Reviewed Original ResearchMeSH KeywordsChronic PainCognitive Behavioral TherapyFemaleHumansInternetInternet-Based InterventionLow Back PainMaleMiddle AgedVeteransConceptsChronic low back painLow back painClinical characteristicsBack painChronic painEASE programParticipant characteristicsInternet-based cognitive behavioural therapy programmeInternet-based cognitive behavioral therapy interventionInternet-based interventionsCognitive behavioral therapy interventionInternet-based programCognitive behavioral therapy programBehavioral therapy interventionBehavioral therapy programRace/ethnicityPain careMean ageNumber of loginsIncreased ageTherapy interventionWeek trialPainTherapy programPredictors of engagementNonsteroidal Anti-inflammatory Drugs vs Cognitive Behavioral Therapy for Arthritis Pain
Fraenkel L, Buta E, Suter L, Dubreuil M, Levy C, Najem C, Brennan M, Corn B, Kerns R, Goulet J. Nonsteroidal Anti-inflammatory Drugs vs Cognitive Behavioral Therapy for Arthritis Pain. JAMA Internal Medicine 2020, 180: 1194-1202. PMID: 32702101, PMCID: PMC7372512, DOI: 10.1001/jamainternmed.2020.2821.Peer-Reviewed Original ResearchMeSH KeywordsAgedAnti-Inflammatory Agents, Non-SteroidalCognitive Behavioral TherapyDouble-Blind MethodFemaleHumansMaleMeloxicamMiddle AgedOsteoarthritis, KneePain MeasurementTelemedicineTreatment OutcomeConceptsNonsteroidal anti-inflammatory drugsWOMAC pain scorePain scoresAnti-inflammatory drugsGlobal ImpressionKnee osteoarthritisMeloxicam groupMcMaster Universities Osteoarthritis Index (WOMAC) pain scoreCurrent nonsteroidal anti-inflammatory drugsLong-term clinical benefitMean differencePain score differenceParticipant global impressionWOMAC disability scoresKnee osteoarthritis painLower extremity disabilityPrimary outcome measureSignificant differencesCognitive behavioral therapy programCognitive behavioral therapyBehavioral therapy programBaseline painOsteoarthritis painTreat basisDisability scoresInternet‐Based Pain Self‐Management for Veterans: Feasibility and Preliminary Efficacy of the Pain EASE Program
Higgins DM, Buta E, Williams DA, Halat A, Bair MJ, Heapy AA, Krein SL, Rajeevan H, Rosen MI, Kerns RD. Internet‐Based Pain Self‐Management for Veterans: Feasibility and Preliminary Efficacy of the Pain EASE Program. Pain Practice 2020, 20: 357-370. PMID: 31778281, DOI: 10.1111/papr.12861.Peer-Reviewed Original ResearchMeSH KeywordsAdultChronic PainCognitive Behavioral TherapyFeasibility StudiesFemaleHumansInternetLow Back PainMaleMiddle AgedPain ManagementSelf-ManagementVeteransConceptsChronic low back painSelf-management programPain interferencePreliminary efficacyInternet-based self-management programPhase IPost-baseline assessmentLow back painPain Self-ManagementPhase IIPreliminary efficacy studyTechnology-delivered interventionsModerate painSecondary outcomesPain intensityBack painAverage ageEfficacy studiesDepression symptomsSubject improvementExpert panelSelf-ManagementSubject changesEASE programWeeks
2019
Further Examination of the Pain Stages of Change Questionnaires Among Chronic Low Back Pain Patients
Mun CJ, Otis JD, Concato J, Reid MC, Burg MM, Czlapinski R, Kerns RD. Further Examination of the Pain Stages of Change Questionnaires Among Chronic Low Back Pain Patients. The Clinical Journal Of Pain 2019, 35: 744-752. PMID: 31149934, DOI: 10.1097/ajp.0000000000000733.Peer-Reviewed Original ResearchConceptsChronic low back pain patientsLow back pain patientsSelf-management approachBack pain patientsCognitive behavioral therapyChronic painDepressive symptom severityPain severityPain patientsPain StagesRegular cognitive behavioural therapySymptom severityVA primary care clinicsChange scoresPrimary care clinicsChange QuestionnaireLong-term functionMaintenance scoresCare clinicsPresent studyPatient readinessPatients' attitudesWeeks posttreatmentSustained benefitTherapeutic mechanism
2018
An evaluation of the feasibility, acceptability, and preliminary efficacy of cognitive-behavioral therapy for opioid use disorder and chronic pain
Barry DT, Beitel M, Cutter CJ, Fiellin DA, Kerns RD, Moore BA, Oberleitner L, Madden LM, Liong C, Ginn J, Schottenfeld RS. An evaluation of the feasibility, acceptability, and preliminary efficacy of cognitive-behavioral therapy for opioid use disorder and chronic pain. Drug And Alcohol Dependence 2018, 194: 460-467. PMID: 30508769, PMCID: PMC6312460, DOI: 10.1016/j.drugalcdep.2018.10.015.Peer-Reviewed Original ResearchConceptsOpioid use disorderCognitive behavioral therapyChronic painPreliminary efficacyDrug counselingUse disordersImproved pain outcomesProportion of patientsMethadone-maintained patientsNonmedical opioid useEnd of treatmentPrimary study aimPatient satisfaction ratingsManualized cognitive behavioral therapyOpioid usePain outcomesPain interferenceClinical trialsStandard drug counselingPatientsMean sessionSecondary aimStudy aimPainPilot studyVeteran Experiences Seeking Non-pharmacologic Approaches for Pain
Giannitrapani K, McCaa M, Haverfield M, Kerns RD, Timko C, Dobscha S, Lorenz K. Veteran Experiences Seeking Non-pharmacologic Approaches for Pain. Military Medicine 2018, 183: e628-e634. PMID: 29590422, DOI: 10.1093/milmed/usy018.Peer-Reviewed Original ResearchConceptsNon-pharmacologic approachesUS military veteransPatient-centered pain careVA health care systemManagement of painNumeric rating scalePrimary care clinicsMilitary veteransPain intensity ratingsSpecific access barriersVA healthcare systemMulti-level barriersHealth care systemVeterans' experiencesFuture implementation effortsPain screeningCare clinicsPain carePrimary careCare coordinationPain studiesPainPain experienceVeterans' knowledgeFemale veteransA Randomized Pilot Trial of a Novel Behavioral Intervention for Chronic Pain Tailored to Individuals with HIV
Merlin JS, Westfall AO, Long D, Davies S, Saag M, Demonte W, Young S, Kerns RD, Bair MJ, Kertesz S, Turan JM, Kilgore M, Clay OJ, Starrels J, Pekmezi D, Johnson MO. A Randomized Pilot Trial of a Novel Behavioral Intervention for Chronic Pain Tailored to Individuals with HIV. AIDS And Behavior 2018, 22: 2733-2742. PMID: 29340913, PMCID: PMC6047927, DOI: 10.1007/s10461-018-2028-2.Peer-Reviewed Original ResearchConceptsChronic painPilot trialBrief Pain Inventory (BPI) total scorePain self-management interventionMedian session attendanceUsual care comparisonRandomized pilot trialSelf-management interventionsNovel behavioral interventionModerate painPain severityPreliminary efficacyIntervention groupSession attendanceCare comparisonsEligibility criteriaControl groupPainInterference ScaleBehavioral interventionsTrialsHIVPreliminary evidenceFull-scale trialEfficacy
2017
Developing a typology of patient-generated behavioral goals for cognitive behavioral therapy for chronic pain (CBT-CP): classification and predicting outcomes
Heapy AA, Wandner L, Driscoll MA, LaChappelle K, Czlapinski R, Fenton BT, Piette JD, Aikens JE, Janevic MR, Kerns RD. Developing a typology of patient-generated behavioral goals for cognitive behavioral therapy for chronic pain (CBT-CP): classification and predicting outcomes. Journal Of Behavioral Medicine 2017, 41: 174-185. PMID: 28936717, DOI: 10.1007/s10865-017-9885-4.Peer-Reviewed Original ResearchMeSH KeywordsAdultChronic PainCognitive Behavioral TherapyFemaleGoalsHumansMaleMiddle AgedPrognosisTreatment OutcomeConceptsCognitive behavioral therapyChronic painYard workTreatment outcomesPhysical activityDepressive symptomsPain-related interferenceWork/schoolPain intensityFunctional statusTreatment goalsPredicting OutcomePatient valuesMeaningful improvementsOutcome domainsBehavioral therapyWellness goalsRecreational activitiesPainTherapyOutcomesSymptomsBehavioral goalsActivityInteractive Voice Response–Based Self-management for Chronic Back Pain: The COPES Noninferiority Randomized Trial
Heapy AA, Higgins DM, Goulet JL, LaChappelle KM, Driscoll MA, Czlapinski RA, Buta E, Piette JD, Krein SL, Kerns RD. Interactive Voice Response–Based Self-management for Chronic Back Pain: The COPES Noninferiority Randomized Trial. JAMA Internal Medicine 2017, 177: 765-773. PMID: 28384682, PMCID: PMC5818820, DOI: 10.1001/jamainternmed.2017.0223.Peer-Reviewed Original ResearchMeSH KeywordsAgedChronic PainCognitive Behavioral TherapyEarly Medical InterventionFemaleHumansLow Back PainMaleMiddle AgedPain ManagementPatient Education as TopicSelf CareSimulation TrainingTelemedicineConceptsPerson cognitive-behavioural therapyChronic back painNumeric rating scaleCognitive behavioral therapyBack painChronic painPrimary outcomeSleep qualityVeterans Affairs Health Care SystemPrespecified noninferiority marginAverage pain intensityNonpharmacologic treatment optionsPain-related interferenceChronic pain treatmentSelf-management trialCognitive behavioral therapy deliveryIndividual CBT sessionsEvidence-based treatmentsQuality of lifeSelf-help manualHealth care systemIVR monitoringNonpharmacologic interventionsSecondary outcomesStandard therapy
2016
Integrated, Team-Based Chronic Pain Management: Bridges from Theory and Research to High Quality Patient Care
Driscoll MA, Kerns RD. Integrated, Team-Based Chronic Pain Management: Bridges from Theory and Research to High Quality Patient Care. Advances In Experimental Medicine And Biology 2016, 904: 131-147. PMID: 26900068, DOI: 10.1007/978-94-017-7537-3_10.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesicsChronic PainCognitive Behavioral TherapyCombined Modality TherapyComplementary TherapiesCost of IllnessDecision MakingDelivery of Health Care, IntegratedEmpathyGoalsHumansModels, NeurologicalModels, PsychologicalPain ClinicsPain ManagementPatient Care TeamProfessional-Patient RelationsQuality of LifeSocioeconomic FactorsConceptsChronic painSignificant public health concernChronic pain managementInterdisciplinary treatment approachBiopsychosocial modelCost of carePublic health concernHigh-quality patient careQuality patient careMental health professionalsPain managementSocioeconomic burdenPhysical functioningPainTreatment approachesHealth professionalsPatient careOptimal managementHealth concernEmotional distressCareCooperative pain education and self-management (COPES): study design and protocol of a randomized non-inferiority trial of an interactive voice response-based self-management intervention for chronic low back pain
Heapy AA, Higgins DM, LaChappelle KM, Kirlin J, Goulet JL, Czlapinski RA, Buta E, Piette JD, Krein SL, Richardson CR, Kerns RD. Cooperative pain education and self-management (COPES): study design and protocol of a randomized non-inferiority trial of an interactive voice response-based self-management intervention for chronic low back pain. BMC Musculoskeletal Disorders 2016, 17: 85. PMID: 26879051, PMCID: PMC4754867, DOI: 10.1186/s12891-016-0924-z.Peer-Reviewed Original ResearchMeSH KeywordsChronic PainCognitive Behavioral TherapyEarly Medical InterventionHumansLow Back PainPain ManagementPain MeasurementPatient Education as TopicSelf CareSimulation TrainingTelemedicineVeteransConceptsChronic low back painLow back painNon-inferiority trialRandomized non-inferiority trialCognitive behavioral therapyPerson cognitive-behavioural therapyBack painClinical outcomesChronic pain conditionsNumeric rating scalePain-related interferencePatient-reported informationSelf-management interventionsEvidence-based treatmentsQuality of lifeUS military veteransStatewide health systemBackgroundThe InstituteIVR monitoringSecondary outcomesMore patientsPain conditionsPain intensityPrimary outcomeChronic pain
2015
National Dissemination of Cognitive-Behavioral Therapy for Chronic Pain in Veterans
Stewart MO, Karlin BE, Murphy JL, Raffa SD, Miller SA, McKellar J, Kerns RD. National Dissemination of Cognitive-Behavioral Therapy for Chronic Pain in Veterans. The Clinical Journal Of Pain 2015, 31: 722-729. PMID: 25171637, DOI: 10.1097/ajp.0000000000000151.Peer-Reviewed Original ResearchConceptsPain-related outcomesCBT-CPQuality of lifeCognitive behavioral therapyHealth care systemVeteran patientsChronic painVeterans Affairs Health Care SystemPatient-reported pain intensityVA health care systemCare systemTherapeutic alliancePain-related cognitionsPain intensityTreat analysisPain interferencePain catastrophizingPatient outcomesSpecialty settingsOverall distressTraining programPatientsWeekly consultationEffect of trainingNational disseminationDoes Change Occur for the Reasons We Think It Does? A Test of Specific Therapeutic Operations During Cognitive-Behavioral Treatment of Chronic Pain
Burns JW, Nielson WR, Jensen MP, Heapy A, Czlapinski R, Kerns RD. Does Change Occur for the Reasons We Think It Does? A Test of Specific Therapeutic Operations During Cognitive-Behavioral Treatment of Chronic Pain. The Clinical Journal Of Pain 2015, 31: 603-611. PMID: 25119513, DOI: 10.1097/ajp.0000000000000141.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyChronic painStandard cognitive behavioral therapyUse of painTreatment-related changesCoping skillsClinical trialsFavorable outcomeCognitive-behavioral treatmentTreatment benefitTherapeutic mechanismPatient expectationsPainWorking allianceSecondary analysisNonspecific factorsExercise useSession threeRelative validityTherapeutic operationsRelaxation skillsInventory subscalesMixed improvementsTreatmentExerciseSpecific and General Therapeutic Mechanisms in Cognitive Behavioral Treatment of Chronic Pain
Burns JW, Nielson WR, Jensen MP, Heapy A, Czlapinski R, Kerns RD. Specific and General Therapeutic Mechanisms in Cognitive Behavioral Treatment of Chronic Pain. Journal Of Consulting And Clinical Psychology 2015, 83: 1-11. PMID: 24979313, DOI: 10.1037/a0037208.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedChronic PainCognitive Behavioral TherapyFemaleHumansMaleMiddle AgedOutcome and Process Assessment, Health CareConceptsCognitive behavioral therapyPain intensityChronic painPatient expectationsPosttreatment changesPotential treatment mechanismsStandard cognitive behavioral therapyPre-post changesPain interferenceCognitive-behavioral treatmentSignificant linear trendTherapeutic mechanismDepressive symptomsDocument efficacyPainCBT conditionBehavioral treatmentBehavioral therapyComparable improvementWeeksCBT mechanismsOutcomesTreatmentSignificant quadratic trendTreatment mechanisms
2014
Can We Improve Cognitive–Behavioral Therapy for Chronic Back Pain Treatment Engagement and Adherence? A Controlled Trial of Tailored Versus Standard Therapy
Kerns RD, Burns JW, Shulman M, Jensen MP, Nielson WR, Czlapinski R, Dallas MI, Chatkoff D, Sellinger J, Heapy A, Rosenberger P. Can We Improve Cognitive–Behavioral Therapy for Chronic Back Pain Treatment Engagement and Adherence? A Controlled Trial of Tailored Versus Standard Therapy. Health Psychology 2014, 33: 938-947. PMID: 24295024, DOI: 10.1037/a0034406.Peer-Reviewed Original ResearchConceptsStandard CBTMotivational enhancement strategiesTreatment engagementSkills practiceCognitive behavioral therapyIndex of engagementBehavioral therapyBehavioral skillsGoal accomplishmentLow dropout ratePosttreatment improvementTreatment participationDaily ratingsOutcomes supportTherapeutic processBaseline measuresEnhancement strategiesMore sessionsParticipants' preferencesChronic back painTCBTParticipantsEngagementOutcome factorsTreatment conditionsThe Feasibility and Acceptability of Groups for Pain Management in Methadone Maintenance Treatment
Barry DT, Savant JD, Beitel M, Cutter CJ, Schottenfeld RS, Kerns RD, Moore BA, Oberleitner L, Joy MT, Keneally N, Liong C, Carroll KM. The Feasibility and Acceptability of Groups for Pain Management in Methadone Maintenance Treatment. Journal Of Addiction Medicine 2014, 8: 338-344. PMID: 25100310, PMCID: PMC4177009, DOI: 10.1097/adm.0000000000000055.Peer-Reviewed Original ResearchMeSH KeywordsAdultCognitive Behavioral TherapyFeasibility StudiesFemaleHumansMaleMethadoneNarcoticsOpiate Substitution TreatmentOpioid-Related DisordersPain ManagementPatient SatisfactionRelaxation TherapyConceptsMethadone maintenance treatmentMaintenance treatmentRelaxation trainingMultimodal pain management approachAcceptability of groupsCharacteristic pain intensityPain management interventionsMethadone-maintained patientsPain management approachesPain intensityPain managementSession attendancePainGroup singingDecreased anxietyMindful walkingPatientsTreatmentAttendanceGroupWalkingManagement interventionsAcceptability
2012
Pain Coping but Not Readiness to Change Is Associated With Pretreatment Pain-related Functioning
Finan PH, Burns JW, Jensen MP, Nielson WR, Kerns RD. Pain Coping but Not Readiness to Change Is Associated With Pretreatment Pain-related Functioning. The Clinical Journal Of Pain 2012, 28: 687-692. PMID: 22688600, DOI: 10.1097/ajp.0b013e3182400867.Peer-Reviewed Original Research