Airway Inflammation and Remodeling in Asthma
ZHU Z, LEE C, ZHENG T, CHUPP G, WANG J, HOMER R, NOBLE P, HAMID Q, ELIAS J. Airway Inflammation and Remodeling in Asthma. American Journal Of Respiratory And Critical Care Medicine 2001, 164: s67-s70. PMID: 11734470, DOI: 10.1164/ajrccm.164.supplement_2.2106070.Peer-Reviewed Original ResearchConceptsAirway fibrosisAsthmatic airwaysIL-11IL-13Asthma-like inflammationExaggerated cytokine productionImportance of airwayMucin gene expressionHyaluronic acid accumulationAirway healingAsthmatic tissuesSevere airwayAirway inflammationAirway remodelingAsthmatic subjectsSubepithelial fibrosisAsthma phenotypesCytokine productionMurine airwaysMucous metaplasiaAirwayTransgenic miceNatural historyInterleukin-11Fibrosis