Cerebral compensation for chronic noradrenergic denervation induced by locus ceruleus lesion: recovery of receptor binding, isoproterenol- induced adenylate cyclase activity, and oxidative metabolism
Harik SI, Duckrow RB, LaManna JC, Rosenthal M, Sharma VK, Banerjee SP. Cerebral compensation for chronic noradrenergic denervation induced by locus ceruleus lesion: recovery of receptor binding, isoproterenol- induced adenylate cyclase activity, and oxidative metabolism. Journal Of Neuroscience 1981, 1: 641-649. PMID: 7346572, PMCID: PMC6564177, DOI: 10.1523/jneurosci.01-06-00641.1981.Peer-Reviewed Original ResearchConceptsLocus ceruleus lesionNoradrenergic denervationCerebral cortexReceptor bindingNoradrenergic receptor bindingOxidative metabolismRat cerebral cortexDirect cortical stimulationVivo oxidative metabolismBlood volume shiftsCyclic AMP generationAdenylate cyclase activityCerebral compensationNoradrenaline depletionLocus ceruleusUnilateral injectionCortical stimulationCerebral noradrenalineLong-term effectsAMP generationMonophosphate generationLesionsDenervationCyclase activityWeeksOxidative metabolic activity of cerebral cortex after fluid-percussion head injury in the cat.
Duckrow R, LaManna J, Rosenthal M, Levasseur J, Patterson J. Oxidative metabolic activity of cerebral cortex after fluid-percussion head injury in the cat. Journal Of Neurosurgery 1981, 54: 607-14. PMID: 7229699, DOI: 10.3171/jns.1981.54.5.0607.Peer-Reviewed Original ResearchConceptsPosttraumatic periodCerebral cortexBlood volumeFluid percussion head injuryCortical blood volumeImmediate posttraumatic periodLocal blood volumeOxidative metabolic activityTransient hypertensionRelationship of metabolismVascular effectsCerebral circulationHead traumaVascular toneCranial windowHead injuryTrauma altersInjuryCortical surfaceCortexCatsMetabolic activityHypertensionReflection spectrophotometryPeriod