2019
Cost-Effectiveness of Alternative Uses of Polyvalent Meningococcal Vaccines in Niger: An Agent-Based Transmission Modeling Study
Arifin SMN, Zimmer C, Trotter C, Colombini A, Sidikou F, LaForce FM, Cohen T, Yaesoubi R. Cost-Effectiveness of Alternative Uses of Polyvalent Meningococcal Vaccines in Niger: An Agent-Based Transmission Modeling Study. Medical Decision Making 2019, 39: 553-567. PMID: 31268405, PMCID: PMC6786941, DOI: 10.1177/0272989x19859899.Peer-Reviewed Original ResearchConceptsReactive campaignsSerogroup replacementConjugate vaccineOne-time catchPolyvalent meningococcal vaccineRoutine infant vaccinationMeningococcal conjugate vaccineMeningococcal polysaccharide vaccineRoutine infant immunizationCurrent vaccination practicesImportant health benefitsCost-effectiveness thresholdStandard cost-effectiveness thresholdsAgent-based transmission modelVaccination seriesImmunization seriesInfant vaccinationInfant immunizationPolysaccharide vaccineMeningococcal vaccineVaccination practicesPolyvalent vaccineLaboratory confirmationMenAfriVacSerogroups A
2018
Accurate quantification of uncertainty in epidemic parameter estimates and predictions using stochastic compartmental models
Zimmer C, Leuba SI, Cohen T, Yaesoubi R. Accurate quantification of uncertainty in epidemic parameter estimates and predictions using stochastic compartmental models. Statistical Methods In Medical Research 2018, 28: 3591-3608. PMID: 30428780, PMCID: PMC6517086, DOI: 10.1177/0962280218805780.Peer-Reviewed Original ResearchConceptsFilter degeneracyParameter estimatesPosterior distributionStochastic transmission-dynamic modelParameter posterior distributionsEpidemic compartmental modelKey epidemic parametersStochastic compartmental modelStochastic systemsPrediction intervalsCompartmental modelMultiple shootingArt calibration methodsEpidemic parametersDegeneracyDynamic modelInfluenza modelMSS approachLong-term predictionTransmission dynamic modelSimulation experimentsCalibration methodUncertaintyEstimatesCompetitive performanceUse of daily Internet search query data improves real-time projections of influenza epidemics
Zimmer C, Leuba SI, Yaesoubi R, Cohen T. Use of daily Internet search query data improves real-time projections of influenza epidemics. Journal Of The Royal Society Interface 2018, 15: 20180220. PMID: 30305417, PMCID: PMC6228485, DOI: 10.1098/rsif.2018.0220.Peer-Reviewed Original ResearchTuberculosis control interventions targeted to previously treated people in a high-incidence setting: a modelling study
Marx FM, Yaesoubi R, Menzies NA, Salomon JA, Bilinski A, Beyers N, Cohen T. Tuberculosis control interventions targeted to previously treated people in a high-incidence setting: a modelling study. The Lancet Global Health 2018, 6: e426-e435. PMID: 29472018, PMCID: PMC5849574, DOI: 10.1016/s2214-109x(18)30022-6.Peer-Reviewed Original ResearchConceptsHigh-incidence settingsIsoniazid preventive therapyPreventive therapyTuberculosis treatmentActive casesHIV prevalenceTuberculosis controlControl interventionsIncident tuberculosis casesPrevious tuberculosis treatmentTuberculosis control interventionsTB case notificationHigh-risk groupTransmission dynamic modelTuberculosis deathsHigh tuberculosisRecurrent diseasePrevalent tuberculosisTuberculosis casesTuberculosis incidenceCase notificationTreatment outcomesTuberculosis morbidityTuberculosis epidemicAdditional interventions
2017
A Likelihood Approach for Real-Time Calibration of Stochastic Compartmental Epidemic Models
Zimmer C, Yaesoubi R, Cohen T. A Likelihood Approach for Real-Time Calibration of Stochastic Compartmental Epidemic Models. PLOS Computational Biology 2017, 13: e1005257. PMID: 28095403, PMCID: PMC5240920, DOI: 10.1371/journal.pcbi.1005257.Peer-Reviewed Original ResearchConceptsParameter estimationStochastic modelLinear noise approximationStochastic transmission-dynamic modelEnsemble Kalman filter methodReal-time parameter estimationKey epidemic parametersParticle filtering methodInfectious individualsStochastic systemsCompartmental epidemic modelLikelihood approximationMultiple shootingNoise approximationBenchmark methodsEpidemic modelPoisson observationsKalman filter methodUnobserved numberAccurate estimatesEpidemic parametersLikelihood approachFiltering methodDynamic modelApproximation
2016
Identifying cost‐effective dynamic policies to control epidemics
Yaesoubi R, Cohen T. Identifying cost‐effective dynamic policies to control epidemics. Statistics In Medicine 2016, 35: 5189-5209. PMID: 27449759, PMCID: PMC5096998, DOI: 10.1002/sim.7047.Peer-Reviewed Original ResearchConceptsNet health benefitHighest net health benefitHealth benefitsTransmission-reducing interventionsDynamic policiesNovel viral pathogensCurrent interventionsHealth policyMathematical decision modelViral pathogensMonetary outcomesPolicy makersInterventionPolicyDecision modelStatic policyEpidemicEpidemic dataVaccinationVaccinePerformance measures
2013
Identifying dynamic tuberculosis case-finding policies for HIV/TB coepidemics
Yaesoubi R, Cohen T. Identifying dynamic tuberculosis case-finding policies for HIV/TB coepidemics. Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: 9457-9462. PMID: 23690585, PMCID: PMC3677479, DOI: 10.1073/pnas.1218770110.Peer-Reviewed Original ResearchConceptsUndiagnosed casesHigh-burden settingsSmear-negative casesTB control programsDuration of roundsBurden settingsTB suspectsTB transmissionAggressive approachOnward transmissionIncremental yieldPopulation healthIncremental benefitInfectious individualsDiagnostic toolControl programsICFPassive caseSymptomsCasesSettingDiagnosis