2020
Adaptive guidelines for the treatment of gonorrhea to increase the effective life span of antibiotics among men who have sex with men in the United States: A mathematical modeling study
Yaesoubi R, Cohen T, Hsu K, Gift TL, Chesson H, Salomon JA, Grad YH. Adaptive guidelines for the treatment of gonorrhea to increase the effective life span of antibiotics among men who have sex with men in the United States: A mathematical modeling study. PLOS Medicine 2020, 17: e1003077. PMID: 32243443, PMCID: PMC7122693, DOI: 10.1371/journal.pmed.1003077.Peer-Reviewed Original ResearchConceptsFirst-line antibioticsPrevalence of resistanceMSM populationGonorrhea casesPrevalence of gonorrheaTreatment of gonorrheaTransmission of gonorrheaIncidence of gonorrhoeaGonococcal antimicrobial resistanceProportion of casesAlternative surveillance strategiesBurden of gonorrheaEffective surveillance systemTreatment guidelinesGonorrhea treatmentGonorrhoea transmissionClinical effectivenessOverall burdenSurveillance estimatesLife spanGonorrheaDrug susceptibilitySurveillance findingsSurveillance strategiesSurveillance program
2018
A Cost-Effectiveness Analysis of a Pediatric Operating Room in Uganda
Yap A, Muzira A, Cheung M, Healy J, Kakembo N, Kisa P, Cunningham D, Youngson G, Sekabira J, Yaesoubi R, Ozgediz D. A Cost-Effectiveness Analysis of a Pediatric Operating Room in Uganda. Surgery 2018, 164: 953-959. PMID: 29801729, PMCID: PMC6399742, DOI: 10.1016/j.surg.2018.03.023.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildChild, PreschoolCost-Benefit AnalysisDecision Making, OrganizationalDecision TreesFemaleHealth Services AccessibilityHealth Services Needs and DemandHumansInfantInfant, NewbornLife ExpectancyMaleModels, EconomicMonte Carlo MethodOperating RoomsQuality-Adjusted Life YearsSurgical Procedures, OperativeTreatment OutcomeUgandaConceptsIncremental cost-effectiveness ratioProbabilistic sensitivity analysesCost-effectiveness ratioPediatric operating roomDisability-adjusted life-year avertedStatistical life approachNet economic benefitsCost-effectiveness thresholdLife-year avertedCost-effectiveness analysisAverage life expectancySub-Saharan AfricaMonetary benefitsSensitivity analysisWorthwhile investmentEconomic benefitsOne-wayLow-income settingsTree templatePediatric surgical capacityLife approachFuture decisionsLife expectancyCostInvestmentTuberculosis control interventions targeted to previously treated people in a high-incidence setting: a modelling study
Marx FM, Yaesoubi R, Menzies NA, Salomon JA, Bilinski A, Beyers N, Cohen T. Tuberculosis control interventions targeted to previously treated people in a high-incidence setting: a modelling study. The Lancet Global Health 2018, 6: e426-e435. PMID: 29472018, PMCID: PMC5849574, DOI: 10.1016/s2214-109x(18)30022-6.Peer-Reviewed Original ResearchConceptsHigh-incidence settingsIsoniazid preventive therapyPreventive therapyTuberculosis treatmentActive casesHIV prevalenceTuberculosis controlControl interventionsIncident tuberculosis casesPrevious tuberculosis treatmentTuberculosis control interventionsTB case notificationHigh-risk groupTransmission dynamic modelTuberculosis deathsHigh tuberculosisRecurrent diseasePrevalent tuberculosisTuberculosis casesTuberculosis incidenceCase notificationTreatment outcomesTuberculosis morbidityTuberculosis epidemicAdditional interventions