2018
Characterization of cell fusion in an experimental mouse model of endometriosis†
Tal A, Tal R, Shaikh S, Gidicsin S, Mamillapalli R, Taylor H. Characterization of cell fusion in an experimental mouse model of endometriosis†. Biology Of Reproduction 2018, 100: 390-397. PMID: 30304517, PMCID: PMC7302516, DOI: 10.1093/biolre/ioy221.Peer-Reviewed Original ResearchConceptsMouse modelLimited proliferative activityFunctional endometrial tissueBone marrow transplantation modelExperimental mouse modelEndometrial stem cellsPrincipal cell sourceRepair/regeneration processBone marrow cellsEndometriosis shareCell fusionEndometrial tissueEndometriosis lesionsEndometriotic lesionsUterine cavityTransplantation modelCell fusion eventsCre-lox systemEndometriosisEpithelial markersStromal compartmentLesionsMarrow cellsProliferative activitySca-1
2008
Specific Induction of Tumor Neovasculature Death by Modified Murine PPE-1 Promoter Armed with HSV-TK
Varda-Bloom N, Hodish I, Shaish A, Greenberger S, Tal R, Feder B, Roitelman J, Breitbart E, Bangio L, Barshack I, Pfeffer R, Harats D. Specific Induction of Tumor Neovasculature Death by Modified Murine PPE-1 Promoter Armed with HSV-TK. Pathobiology 2008, 75: 346-355. PMID: 19096230, DOI: 10.1159/000164219.Peer-Reviewed Original ResearchConceptsHSV-TKSimplex virus thymidine kinaseHSV-TK geneTherapeutic genesVirus thymidine kinaseGene therapyMurine preproendothelin-1 promoterAdenoviral vectorPreproendothelin-1 promoterReporter geneTissue specificityTumor neovasculaturePromoterSpecific inductionGenesHigh expressionTumor angiogenesisMetastasis developmentExpressionNeovasculatureMouse modelKinaseSelectivityEfficiencySpecificity