1995
The NS1 polypeptide of the murine parvovirus minute virus of mice binds to DNA sequences containing the motif [ACCA]2-3
Cotmore S, Christensen J, Nüesch J, Tattersall P. The NS1 polypeptide of the murine parvovirus minute virus of mice binds to DNA sequences containing the motif [ACCA]2-3. Journal Of Virology 1995, 69: 1652-1660. PMID: 7853501, PMCID: PMC188764, DOI: 10.1128/jvi.69.3.1652-1660.1995.Peer-Reviewed Original Research
1994
An asymmetric nucleotide in the parvoviral 3′ hairpin directs segregation of a single active origin of DNA replication.
Cotmore S, Tattersall P. An asymmetric nucleotide in the parvoviral 3′ hairpin directs segregation of a single active origin of DNA replication. The EMBO Journal 1994, 13: 4145-4152. PMID: 8076610, PMCID: PMC395337, DOI: 10.1002/j.1460-2075.1994.tb06732.x.Peer-Reviewed Original Research
1993
Nuclear Targeting of the Parvoviral Replicator Molecule NS1: Evidence for Self-Association Prior to Nuclear Transport
Nüesch J, Tattersall P. Nuclear Targeting of the Parvoviral Replicator Molecule NS1: Evidence for Self-Association Prior to Nuclear Transport. Virology 1993, 196: 637-651. PMID: 8372437, DOI: 10.1006/viro.1993.1520.Peer-Reviewed Original ResearchConceptsNuclear localizationMutant NS1 proteinsNS1 polypeptideMutant NS1Nuclear localization signalNS1 proteinMajor non-structural proteinsAmino acid substitutionsParvovirus minute virusNon-structural proteinsLocalization signalPutative NTPNuclear transportLysine motifNuclear targetingMammalian cellsSubstitution mutantsExpression systemAcid substitutionsFrame deletionDouble lysineProteinMinute virusSubcellular fractionsViral DNA
1992
The pathogenesis of infection with minute virus of mice depends on expression of the small nonstructural protein NS2 and on the genotype of the allotropic determinants VP1 and VP2
Brownstein D, Smith A, Johnson E, Pintel D, Naeger L, Tattersall P. The pathogenesis of infection with minute virus of mice depends on expression of the small nonstructural protein NS2 and on the genotype of the allotropic determinants VP1 and VP2. Journal Of Virology 1992, 66: 3118-3124. PMID: 1373202, PMCID: PMC241074, DOI: 10.1128/jvi.66.5.3118-3124.1992.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornCapsidDNA, ViralEpitopesGenetic VariationImmunohistochemistryMiceMice, Inbred C3HMinute virus of miceMutagenesisNucleic Acid HybridizationParvoviridae InfectionsStructure-Activity RelationshipTissue DistributionViral Core ProteinsViral Nonstructural ProteinsVirulenceConceptsPathogenesis of infectionAsymptomatic infectionMultiple organsViral capsid antigenMesenteric lymph nodesSmooth muscle cellsSame target cellsMVMi infectionLymph nodesCapsid antigenMVMp infectionLethal infectionC3H/Lymphoid cellsTarget organsSimilar dosesAllotropic determinantMinute virusInfectious virusVirus titrationInfectionMuscle cellsMiceTitersTarget cells