2008
CLINICAL STUDY: Subjective responses and cardiovascular effects of self‐administered cocaine in cocaine‐abusing men and women
Lynch WJ, Kalayasiri R, Sughondhabirom A, Pittman B, Coric V, Morgan PT, Malison RT. CLINICAL STUDY: Subjective responses and cardiovascular effects of self‐administered cocaine in cocaine‐abusing men and women. Addiction Biology 2008, 13: 403-410. PMID: 18782384, PMCID: PMC3690939, DOI: 10.1111/j.1369-1600.2008.00115.x.Peer-Reviewed Original ResearchConceptsSelf-administer cocaineSelf-administered cocaine infusionsDiastolic blood pressureSubjective effect measuresCocaine-induced increasesCocaine self-administration sessionsFeelings of hungerFixed ratio 1Cocaine-abusing menSelf-administration sessionsTime-dependent increaseCardiovascular effectsBlood pressureCardiovascular responsesHormonal influencesCocaine abuseSecondary analysisCocaine infusionsHuman laboratoryCardiovascular measuresEffect measuresWomenCocaineMenSignificant main effect
2007
Altered levels of sex and stress steroid hormones assessed daily over a 28-day cycle in early abstinent cocaine-dependent females
Fox HC, Hong KA, Paliwal P, Morgan PT, Sinha R. Altered levels of sex and stress steroid hormones assessed daily over a 28-day cycle in early abstinent cocaine-dependent females. Psychopharmacology 2007, 195: 527-536. PMID: 17891383, PMCID: PMC2746368, DOI: 10.1007/s00213-007-0936-3.Peer-Reviewed Original ResearchConceptsMenstrual cycleSex hormonesHealthy femalesEstradiol/progesterone ratioSteroid hormonesFirst monthChronic cocaine abuseSex steroid hormonesLevels of cortisolMood rating scalesStress steroid hormonesDrug-seeking behaviorProgesterone ratioHealthy controlsInpatient treatmentObjectivesThe current studyEvidence of alterationsBrain stressCocaine cravingCocaine abuseSalivary samplesCocaine abstinenceCocaine dependenceCocaine reinforcementCocaine patients