2010
Ankyrin recognizes both surface character and shape of the 14–15 di-repeat of β-spectrin
La-Borde PJ, Stabach PR, Simonović I, Morrow JS, Simonović M. Ankyrin recognizes both surface character and shape of the 14–15 di-repeat of β-spectrin. Biochemical And Biophysical Research Communications 2010, 392: 490-494. PMID: 20079712, PMCID: PMC2839365, DOI: 10.1016/j.bbrc.2010.01.046.Peer-Reviewed Original ResearchConceptsMinimal recognition motifRecognition motifMembrane protein traffickingSpectrin-based cytoskeletonDistinct recognition mechanismsSite-directed mutagenesisComplementary surface chargesHigh-affinity complexProtein traffickingMembrane organizationBeta spectrinLinker mutationsΒ-spectrinBinding surfaceIsothermal titration calorimetryAnkyrinRecognition mechanismTitration calorimetry
2008
Ankyrin facilitates intracellular trafficking of α1-Na+-K+-ATPase in polarized cells
Stabach PR, Devarajan P, Stankewich MC, Bannykh S, Morrow JS. Ankyrin facilitates intracellular trafficking of α1-Na+-K+-ATPase in polarized cells. American Journal Of Physiology - Cell Physiology 2008, 295: c1202-c1214. PMID: 18768923, PMCID: PMC2584975, DOI: 10.1152/ajpcell.00273.2008.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnkyrin RepeatAnkyrinsCell PolarityChlorocebus aethiopsCOS CellsCytoplasmDogsEndoplasmic ReticulumGolgi ApparatusHumansMembrane GlycoproteinsMonomeric GTP-Binding ProteinsProtein ConformationProtein FoldingProtein Sorting SignalsProtein TransportRatsRecombinant Fusion ProteinsRNA InterferenceRNA, Small InterferingSodium-Potassium-Exchanging ATPaseTime FactorsTransfectionViral Envelope ProteinsConceptsEndoplasmic reticulumSecretory pathwayPlasma membraneVesicular stomatitis virus G proteinMadin-Darby canine kidney cellsVirus G proteinSmall hairpin RNACanine kidney cellsGolgi traffickingAnkyrin RGolgi transportSemipermeabilized cellsER retentionCytoplasmic domainMembrane proteinsAssembly pathwayProtein ankyrinIntracellular traffickingAnkyrinFusion proteinSimilar phenotypeG proteinsSuch phenotypesHairpin RNACultured cells