2023
Integrating Right Ventricular Pressure Waveform Analysis With Two-Point Volume Measurement for Quantification of Systolic and Diastolic Function: Experimental Validation and Clinical Application
Heerdt P, Martin-Flores M, Oakland H, Joseph P, Singh I. Integrating Right Ventricular Pressure Waveform Analysis With Two-Point Volume Measurement for Quantification of Systolic and Diastolic Function: Experimental Validation and Clinical Application. Journal Of Cardiothoracic And Vascular Anesthesia 2023, 37: 1929-1937. PMID: 37422337, PMCID: PMC10529383, DOI: 10.1053/j.jvca.2023.06.011.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDiastoleHeart VentriclesHumansRetrospective StudiesStroke VolumeSwineSystoleVentricular Dysfunction, RightVentricular Function, RightVentricular PressureConceptsRight heart catheterizationHeart catheterizationDiastolic functionRV volumesBeat measuresDiagnostic right heart catheterizationReference standardRight ventricular contractilityEnd-diastolic pressurePressure waveform analysisEnd-systolic elastancePotential clinical utilityClinical applicationRV volume measurementsVolume measurementsRV contractilityRV systolicVentricular contractilityRV pressureBland-Altman analysisClinical utilityAnesthetized swineNitric oxideExperimental modelContractility
1998
Disparity of isoflurane effects on left and right ventricular afterload and hydraulic power generation in swine.
Heerdt P, Gandhi C, Dickstein M. Disparity of isoflurane effects on left and right ventricular afterload and hydraulic power generation in swine. Anesthesia & Analgesia 1998, 87: 511-21. PMID: 9728819, DOI: 10.1097/00000539-199809000-00002.Peer-Reviewed Original ResearchConceptsPreload recruitable stroke work slopeDose-related decreaseRight ventricleLeft ventricleISO groupMinimum alveolar anesthetic concentration (MAC) isofluraneIso animalsPulmonary arterial blood flowIsoflurane-induced alterationsRight ventricular afterloadTotal arterial resistanceDose-related effectsEffects of isofluranePeak systolic pressureAutonomic nervous activityArterial blood flowGroups of swineRegional segment lengthVolatile Anesthetic EffectsEjection of bloodBiventricular contractilityRV contractilityVascular effectsVentricular afterloadSystolic pressureDisparity of Isoflurane Effects on Left and Right Ventricular Afterload and Hydraulic Power Generation in Swine
Heerdt P, Gandhi C, Dickstein M. Disparity of Isoflurane Effects on Left and Right Ventricular Afterload and Hydraulic Power Generation in Swine. Anesthesia & Analgesia 1998, 87: 511-521.. DOI: 10.1213/00000539-199809000-00002.Peer-Reviewed Original ResearchConceptsPreload recruitable stroke work slopeDose-related decreaseRight ventricleLeft ventricleISO groupMinimum alveolar anesthetic concentration (MAC) isofluraneIso animalsPulmonary arterial blood flowIsoflurane-induced alterationsTotal arterial resistanceDose-related effectsEffects of isofluranePeak systolic pressureAutonomic nervous activityArterial blood flowGroups of swineRegional segment lengthVolatile Anesthetic EffectsEjection of bloodBiventricular contractilityRV contractilityVascular effectsVentricular afterloadSystolic pressureLV afterload
1996
Nitric oxide synthesis inhibition and right ventricular systolic function in swine
Heerdt P, Pleimann B. Nitric oxide synthesis inhibition and right ventricular systolic function in swine. Journal Of Cardiothoracic And Vascular Anesthesia 1996, 10: 909-914. PMID: 8969400, DOI: 10.1016/s1053-0770(96)80055-3.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDose-Response Relationship, DrugNG-Nitroarginine Methyl EsterNitric OxideNitric Oxide SynthaseProspective StudiesSwineSystoleVentricular Function, RightConceptsRV end-diastolic pressureTotal arterial resistanceL-NAMERV afterloadPA elastanceArterial resistanceNitric oxide synthesis inhibitor NG-nitroNitric oxide synthesis inhibitionRight ventricular systolic functionL-arginine methyl esterMean PA pressurePulmonary arterial pressureRight ventricular contractilityVentricular systolic functionEnd-diastolic pressureIndex of contractilityPeak ejection rateUniversity animal laboratoryLarge pulmonary vesselsIndex of RVRV powerArterial pressureSystolic functionNG-nitroResistance vessels