2010
Bivalirudin utilization in cardiac surgery: shifting anticoagulation from indirect to direct thrombin inhibition
Anand SX, Viles-Gonzalez JF, Mahboobi SK, Heerdt PM. Bivalirudin utilization in cardiac surgery: shifting anticoagulation from indirect to direct thrombin inhibition. Journal Canadien D'anesthésie 2010, 58: 296-311. PMID: 21136312, DOI: 10.1007/s12630-010-9423-0.Peer-Reviewed Original ResearchMeSH KeywordsAntithrombinsCardiac Surgical ProceduresCardiopulmonary BypassHeparinHirudinsHumansPeptide FragmentsRecombinant ProteinsThrombocytopeniaVascular PatencyConceptsVascular graft patencyCardiac surgerySurgical proceduresGraft patencyCoronary artery bypass graft proceduresThrombin inhibitionCardiac Surgery (SYNTAX) trialBypass graft proceduresCardiac surgical proceduresVascular surgical proceduresOptimal clinical outcomesDirect thrombin inhibitionAdditional relevant articlesAnticoagulation protocolCardiopulmonary bypassUnfractionated heparinClinical outcomesSimilar safetySurgery TrialEfficacy profilePotential complicationsGraft proceduresUnited States National LibraryCardiac anesthesiologistsReference lists
2007
Differential regulation of protein phosphatase-1I by neurabin
Bullock SA, Platholi J, Gjyrezi A, Heerdt PM, Tung HY, Hemmings HC. Differential regulation of protein phosphatase-1I by neurabin. Biochemical And Biophysical Research Communications 2007, 358: 140-144. PMID: 17467665, PMCID: PMC1989152, DOI: 10.1016/j.bbrc.2007.04.076.Peer-Reviewed Original ResearchConceptsProtein phosphatase 1Phosphatase 1Protein phosphatase 1IProtein phosphataseActivation domainMultimeric complexesRegulatory subunitCatalytic subunitSubcellular localizationProtein kinaseSubstrate specificityRegulatory proteinsUnidentified proteinsNeurabinDifferential regulationNovel mechanismProteinSubunitsRegulationMajor formDistinct formsDependent formKinaseActinActivator