2020
Clinical outcomes and characteristics of patients with TP53-mutated acute myeloid leukemia or myelodysplastic syndromes: a single center experience*
Bewersdorf JP, Shallis RM, Gowda L, Wei W, Hager K, Isufi I, Kim TK, Pillai MM, Seropian S, Podoltsev NA, Gore SD, Siddon AJ, Zeidan AM. Clinical outcomes and characteristics of patients with TP53-mutated acute myeloid leukemia or myelodysplastic syndromes: a single center experience*. Leukemia & Lymphoma 2020, 61: 2180-2190. PMID: 32362171, PMCID: PMC7603787, DOI: 10.1080/10428194.2020.1759051.Peer-Reviewed Original ResearchConceptsAcute myeloid leukemiaMedian overall survivalTherapy-related malignanciesOverall survivalMyelodysplastic syndromeMyeloid leukemiaAllogeneic hematopoietic stem cell transplantLonger median overall survivalSingle-center retrospective studyComplex karyotypeHematopoietic stem cell transplantIntensive chemotherapy approachesYale Cancer CenterCharacteristics of patientsSingle-center experienceMinority of patientsStem cell transplantLong-term survivalLow response rateIntensive chemotherapyCenter experienceClinicopathologic characteristicsAdverse prognosisAML patientsCell transplant
2011
Post-Transplantation Lymphoproliferative Disorders (PTLD) Management in Solid Organ Transplantation (SOT) Recipients
Podoltsev N, Bustillo I, Yao X, Liu H, Cooper D. Post-Transplantation Lymphoproliferative Disorders (PTLD) Management in Solid Organ Transplantation (SOT) Recipients. Blood 2011, 118: 4941. DOI: 10.1182/blood.v118.21.4941.4941.Peer-Reviewed Original ResearchReduction of immunosuppressionDiffuse large B-cell lymphomaYale Cancer CenterMonomorphic PTLDPolymorphic PTLDPTLD patientsGraft lossGraft rejectionComplete responseB cellsMedian progression-free survivalSolid organ transplantation recipientsEpstein-Barr virus infectionLarge B-cell lymphomaEBV-negative tumorsGraft loss rateStandard immunosuppressive agentsMedian overall survivalAdvanced stage diseaseConsequence of immunosuppressionEBV-positive lymphomasOrgan transplantation recipientsProgression-free survivalRetrospective cohort trialTime of diagnosis