2023
Extrauterine epithelioid trophoblastic tumour and its somatic carcinoma mimics: short tandem repeat genotyping meets the diagnostic challenges
Niu N, Ordulu Z, Burak Z, Buza N, Hui P. Extrauterine epithelioid trophoblastic tumour and its somatic carcinoma mimics: short tandem repeat genotyping meets the diagnostic challenges. Histopathology 2023, 84: 325-335. PMID: 37743102, DOI: 10.1111/his.15054.Peer-Reviewed Original ResearchConceptsEpithelioid trophoblastic tumorGestational trophoblastic tumorsTrophoblastic tumorExtrauterine sitesSomatic carcinomasDifferential diagnosisDiagnosis of ETTExtrauterine epithelioid trophoblastic tumorsTriple-negative breast carcinomaTrophoblastic differentiationMetastatic triple-negative breast carcinomaPrimary lung carcinomaMain differential diagnosisMajor differential diagnosisEctopic gestationImmunohistochemical featuresDiagnostic challengeMetastatic tumorsLung carcinomaBreast carcinomaPatient managementEpithelioid malignanciesImmunohistochemical levelCarcinomaTumor tissue
2021
Genotyping diagnosis of gestational trophoblastic disease: frontiers in precision medicine
Buza N, Hui P. Genotyping diagnosis of gestational trophoblastic disease: frontiers in precision medicine. Modern Pathology 2021, 34: 1658-1672. PMID: 34088998, DOI: 10.1038/s41379-021-00831-9.Peer-Reviewed Original ResearchConceptsGestational trophoblastic diseaseTrophoblastic diseaseGestational trophoblastic tumorsGestational trophoblastic neoplasiaRoutine diagnostic workupDNA genotypingSignificant clinical relevancePowerful ancillary toolFIGO/Genetic zygosityGestational eventIndex gestationTrophoblastic tumorTrophoblastic neoplasiaGestational choriocarcinomaPrognostic stratificationDiagnostic workupPrognostic assessmentClinical relevanceClinical practiceGestational originMolecular diagnostic capabilitiesPatient careSporadic hydatidiformCopy number alterations