2021
Acute-Phase Levels of CXCL8 as Risk Factor for Chronic Arthralgia Following Chikungunya Virus Infection
Jacob-Nascimento L, Carvalho C, Silva M, Kikuti M, Anjos R, Fradico J, Campi-Azevedo A, Tauro L, Campos G, dos Santos Moreira P, Portilho M, Martins-Filho O, Ribeiro G, Reis M. Acute-Phase Levels of CXCL8 as Risk Factor for Chronic Arthralgia Following Chikungunya Virus Infection. Frontiers In Immunology 2021, 12: 744183. PMID: 34659240, PMCID: PMC8517435, DOI: 10.3389/fimmu.2021.744183.Peer-Reviewed Original ResearchConceptsChikungunya virus infectionCHIKV infectionHealthy controlsIL-12IL-1βVirus infectionFlow cytometric bead arrayAcute phase immune responseAcute CHIKV infectionAnti-CHIKV IgMAcute-phase samplesCytometric bead arrayAcute febrile diseaseAcute-phase levelsCHIKV patientsSerum chemokinesCXCL10 levelsPain persistenceIL-10Cytokine kineticsMultivariable analysisCXCL8 levelsIL-6Female sexIL-2Risk of chronic arthralgia and impact of pain on daily activities in a cohort of patients with chikungunya virus infection from Brazil
Silva M, Kikuti M, Anjos R, Portilho M, Santos V, Gonçalves T, Tauro L, Moreira P, Jacob-Nascimento L, Santana P, Campos G, Siqueira A, Kitron U, Reis M, Ribeiro G. Risk of chronic arthralgia and impact of pain on daily activities in a cohort of patients with chikungunya virus infection from Brazil. International Journal Of Infectious Diseases 2021, 105: 608-616. PMID: 33684559, DOI: 10.1016/j.ijid.2021.03.003.Peer-Reviewed Original ResearchConceptsChronic arthralgiaChikungunya virus infectionRisk factorsVirus infectionDaily activitiesAcute febrile illnessIndependent risk factorPersistence of painCohort of patientsImpact of painProgression of diseaseTranscriptase-polymerase chain reactionPersistent arthralgiaFebrile illnessSubstantial disabilityViral loadFemale sexPolymerase chain reactionIgM enzymeArthralgiaSurveillance studyChikungunya virusDengue virusPatientsImmunosorbent assay
2020
Meningococcal carriage in young adults six years after meningococcal C conjugate (MCC) vaccine catch-up campaign in Salvador, Brazil
Ferreira V, Ferreira Í, Chang H, Nunes A, Topaz N, Pimentel E, Moura A, Ribeiro G, Feitosa C, Reis M, Wang X, Campos L. Meningococcal carriage in young adults six years after meningococcal C conjugate (MCC) vaccine catch-up campaign in Salvador, Brazil. Vaccine 2020, 38: 2995-3002. PMID: 32115294, DOI: 10.1016/j.vaccine.2020.02.050.Peer-Reviewed Original ResearchConceptsMeningococcal carriageCarriage prevalenceRT-PCRN. meningitidisYoung adultsMeningococcal carriage studyMeningococcal serogroup CCross-sectional studyMeningococcal carriage prevalenceAppropriate vaccination strategiesStandard microbiology methodsSix yearsMeningococcal carriage isolatesNG isolatesMale sexSerogroup CHerd protectionVaccination strategiesCarriage isolatesCarriage studiesOropharyngeal swabsReal-time PCRNull genotypeContinuous vaccinationNeisseria meningitidisInfluence of Rainfall on Leptospira Infection and Disease in a Tropical Urban Setting, Brazil - Volume 26, Number 2—February 2020 - Emerging Infectious Diseases journal - CDC
Hacker KP, Sacramento GA, Cruz JS, de Oliveira D, Nery N, Lindow JC, Carvalho M, Hagan J, Diggle PJ, Begon M, Reis MG, Wunder EA, Ko AI, Costa F. Influence of Rainfall on Leptospira Infection and Disease in a Tropical Urban Setting, Brazil - Volume 26, Number 2—February 2020 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2020, 26: 311-314. PMID: 31961288, PMCID: PMC6986844, DOI: 10.3201/eid2602.190102.Peer-Reviewed Original Research
2019
Evaluation of two commercially available chikungunya virus IgM enzyme-linked immunoassays (ELISA) in a setting of concomitant transmission of chikungunya, dengue and Zika viruses
Kikuti M, Tauro L, Moreira P, Nascimento L, Portilho M, Soares G, Weaver S, Reis M, Kitron U, Ribeiro G. Evaluation of two commercially available chikungunya virus IgM enzyme-linked immunoassays (ELISA) in a setting of concomitant transmission of chikungunya, dengue and Zika viruses. International Journal Of Infectious Diseases 2019, 91: 38-43. PMID: 31704226, DOI: 10.1016/j.ijid.2019.11.001.Peer-Reviewed Original ResearchConceptsConvalescent samplesIgM enzymeRT-PCRZika virus transmissionNegative patientsCHIKV infectionAcute samplesZIKV casesConvalescent seraSurveillance studyCHIKV transmissionZika virusCHIKV casesDiagnostic performanceLow specificityVirus transmissionEquivocal resultsTest sensitivitySerumELISA specificityPatientsHigh rateDengueConcomitant transmissionMore equivocal resultsAccuracy of the SD BIOLINE Dengue Duo for rapid point-of-care diagnosis of dengue
Kikuti M, Cruz J, Rodrigues M, Tavares A, Paploski I, Silva M, Santana P, Tauro L, Silva G, Campos G, Araújo J, Kitron U, Reis M, Ribeiro G. Accuracy of the SD BIOLINE Dengue Duo for rapid point-of-care diagnosis of dengue. PLOS ONE 2019, 14: e0213301. PMID: 30840708, PMCID: PMC6402663, DOI: 10.1371/journal.pone.0213301.Peer-Reviewed Original ResearchConceptsRapid diagnosis testsNon-dengue febrile patientsFebrile patientsHealthy controlsBlood donorsLaboratory-confirmed dengue casesSD BIOLINE Dengue DuoSecondary DENV infectionDengue virus antigenAcute-phase seraDengue diagnostic testsRepresentative serum samplesDengue-endemic regionsDengue-endemic areasSample of casesDENV antibodiesDENV infectionNS1 ELISAPrimary infectionDengue diagnosisMedical treatment decisionsTreatment decisionsVirus antigenRDT accuracyRDT sensitivityA localized outbreak of Chikungunya virus in Salvador, Bahia, Brazil
Tauro L, Cardoso C, Souza R, Nascimento L, dos Santos D, Campos G, Sardi S, dos Reis O, Reis M, Kitron U, Ribeiro G. A localized outbreak of Chikungunya virus in Salvador, Bahia, Brazil. Memórias Do Instituto Oswaldo Cruz 2019, 114: e180597. PMID: 30843962, PMCID: PMC6396974, DOI: 10.1590/0074-02760180597.Peer-Reviewed Original Research
2016
Genetic profiles and antimicrobial resistance of Streptococcus pneumoniae non-PCV10 serotype isolates recovered from meningitis cases in Salvador, Brazil
Azevedo J, Dos Anjos ES, Cordeiro S, Dos Santos M, Escobar E, Lobo P, Carvalho MD, Reis M, Reis J, Campos L. Genetic profiles and antimicrobial resistance of Streptococcus pneumoniae non-PCV10 serotype isolates recovered from meningitis cases in Salvador, Brazil. Journal Of Medical Microbiology 2016, 65: 1164-1170. PMID: 27599851, DOI: 10.1099/jmm.0.000346.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedBrazilChildChild, PreschoolDrug Resistance, BacterialElectrophoresis, Gel, Pulsed-FieldFemaleGenetic VariationGenotypeHospitalsHumansInfantMaleMeningitis, PneumococcalMicrobial Sensitivity TestsMiddle AgedMolecular EpidemiologyMultilocus Sequence TypingMultiplex Polymerase Chain ReactionPneumococcal VaccinesSerogroupSerotypingStreptococcus pneumoniaeYoung AdultConceptsPost-vaccine periodMulti-locus sequence typing resultsIntroduction of PCV10Non-vaccine serotypesCases of meningitisPneumococcal conjugate vaccineBenefits of vaccinationChildhood vaccination programsAntimicrobial susceptibility testingMulti-locus sequence typingPCV10 introductionPneumococcal meningitisConjugate vaccineReference hospitalSerotype 19AMeningitis casesSerotype 12FVaccination programMore antibioticsSerotype isolatesQuellung reactionE-testStreptococcus pneumoniaeMeningitisSusceptibility testing
2013
Longitudinal surveillance for meningitis by Acinetobacter in a large urban setting in Brazil
Coelho-Souza T, Reis J, Martins N, Martins I, Menezes A, Reis M, Silva N, Dias R, Riley L, Moreira B. Longitudinal surveillance for meningitis by Acinetobacter in a large urban setting in Brazil. Clinical Microbiology And Infection 2013, 19: e241-e244. PMID: 23398654, PMCID: PMC3625502, DOI: 10.1111/1469-0691.12145.Peer-Reviewed Original ResearchMeSH KeywordsAcinetobacter baumanniiAcinetobacter InfectionsAdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsBrazilCarbapenemsChildChild, PreschoolColistinDrug Resistance, Multiple, BacterialEpidemiological MonitoringFemaleHumansMaleMeningitis, BacterialMiddle AgedMolecular EpidemiologyMultilocus Sequence TypingUrban PopulationYoung AdultConceptsMultilocus sequence typingA. baumanniiCarbapenem resistanceClonal complexesDissemination of infectionLongitudinal surveillanceAcinetobacter baumanniiLarge urban settingMeningitisStudy aimBaumanniiSequence typingUrban settingsAntimicrobial agentsSurveillance systemSurveillanceColistinInfectionSetting
2009
Risk factors for failure to complete a course of latent tuberculosis infection treatment in Salvador, Brazil.
Machado A, Finkmoore B, Emodi K, Takenami I, Barbosa T, Tavares M, Reis M, Arruda S, Riley L. Risk factors for failure to complete a course of latent tuberculosis infection treatment in Salvador, Brazil. The International Journal Of Tuberculosis And Lung Disease 2009, 13: 719-25. PMID: 19460247.Peer-Reviewed Original ResearchConceptsHousehold contactsLatent tuberculosis infectionLTBI treatmentLatent tuberculosis infection treatmentTB-endemic countriesRisks of treatmentHigh-risk populationPulmonary TBMedication intoleranceTuberculosis infectionTuberculosis controlRisk factorsHigh riskSide effectsInfection treatmentHospitalVisitsMonthsTreatmentFollowINHRiskTBRegimenPatients