2016
Leptospira in breast tissue and milk of urban Norway rats (Rattus norvegicus)
DE OLIVEIRA D, FIGUEIRA CP, ZHAN L, PERTILE AC, PEDRA GG, GUSMÃO IM, WUNDER EA, RODRIGUES G, RAMOS EA, KO AI, CHILDS JE, REIS MG, COSTA F. Leptospira in breast tissue and milk of urban Norway rats (Rattus norvegicus). Epidemiology And Infection 2016, 144: 2420-2429. PMID: 27019024, PMCID: PMC5437553, DOI: 10.1017/s0950268816000637.Peer-Reviewed Original ResearchConceptsPolymerase chain reactionBreast tissuePresence of leptospiresNorway ratsMajor public health concernMilk-borne transmissionMajor pathological changesReal-time polymerase chain reactionPublic health concernQuantitative real-time polymerase chain reactionPathogenic Leptospira sppBreast tissue samplesChronic carriagePathological changesLactating ratsRatsHealth concernImmunofluorescence assaysLeptospira sppGenus LeptospiraTissue samplesUrban slumsChain reactionLeptospiresLeptospira
2007
Morphological Alterations in the Kidney of Rats with Natural and Experimental Leptospira Infection
de Faria M, Athanazio DA, Ramos E, Silva EF, Reis MG, Ko AI. Morphological Alterations in the Kidney of Rats with Natural and Experimental Leptospira Infection. Journal Of Comparative Pathology 2007, 137: 231-238. PMID: 17996544, DOI: 10.1016/j.jcpa.2007.08.001.Peer-Reviewed Original ResearchConceptsInterstitial nephritisPathology of leptospirosisKidneys of ratsMorphological alterationsPathogenesis of leptospirosisFiocruz L1-130Leptospiral diseaseWistar ratsLeptospira infectionPathological changesUrban outbreaksRecreational exposureHuman infectionsL1-130RatsWidespread anthropozoonosisKidneyLeptospira interrogansLeptospirosisNephritisInfectionDiseaseEmergent diseaseMammalian reservoirsHost resistance