2012
Soluble Vascular Cell Adhesion Molecule Levels, Endothelin-1 and Endothelial Nitric Oxide Synthase Gene Polymorphisms: Association with Clinical Symptoms in Sickle Cell Anemia.
Vilas-Boas W, Figueiredo C, Cerqueira B, Pitanga T, Zanette A, Reis M, Goncalves M. Soluble Vascular Cell Adhesion Molecule Levels, Endothelin-1 and Endothelial Nitric Oxide Synthase Gene Polymorphisms: Association with Clinical Symptoms in Sickle Cell Anemia. Blood 2012, 120: 2118. DOI: 10.1182/blood.v120.21.2118.2118.Peer-Reviewed Original ResearchAcute chest syndromeT gene polymorphismEndothelial nitric oxide synthaseSoluble adhesion moleculesAdhesion molecule-1Endothelin-1HbSS patientsENOS -786TGene polymorphismsMedical historyMolecule-1Vascular cell adhesion molecule levelsEndothelial nitric oxide synthase gene polymorphismsSoluble intercellular adhesion molecule-1Nitric oxide synthase gene polymorphismsC gene promoter polymorphismsCell adhesion molecule levelsNitric oxide synthesis pathwayVascular cell adhesion molecule-1Intercellular adhesion molecule-1Adhesion moleculesCell adhesion molecule-1Levels of sICAMAdhesion molecule levelsIncreased inflammatory state
2011
Lymphocyte Surface Molecule Expression on Basal State and After Challenge: Association of Clinical Profile, Inflammation, Hematological and Biochemical Markers in Sickle Cell Anemia Patients
Cerqueira B, Vilas-Boas W, Zanette A, Clarencio J, Salvino M, Cezar R, Andrade D, Reis M, Goncalves M. Lymphocyte Surface Molecule Expression on Basal State and After Challenge: Association of Clinical Profile, Inflammation, Hematological and Biochemical Markers in Sickle Cell Anemia Patients. Blood 2011, 118: 2146. DOI: 10.1182/blood.v118.21.2146.2146.Peer-Reviewed Original ResearchSickle cell anemia patientsSoluble adhesion moleculesSickle cell anemiaSurface molecule expressionSCA patientsControl groupAnemia patientsAdhesion moleculesLymphocyte expressionLPS challengeMedical historyCD18 expressionMolecule expressionSoluble vascular adhesion moleculeBasal statePro-inflammatory interactionsEffector immune responsesVaso-occlusive episodesExpression of CD62LMarkers of inflammationChronic inflammatory stateTNF-alpha valuesVascular adhesion moleculesComplete medical historyExpression of CD11b
2009
Adhesion Molecules Interaction with Markers of Lipid Metabolism, Hemolysis, Endothelial Dysfunction and Medical Histories Among Steady-State Sickle Cell Anemia Patients.
Cerqueira B, Boas W, Clarêncio J, Andrade D, Zanette A, Reis M, Neto J, Cesar R, Goncalves M. Adhesion Molecules Interaction with Markers of Lipid Metabolism, Hemolysis, Endothelial Dysfunction and Medical Histories Among Steady-State Sickle Cell Anemia Patients. Blood 2009, 114: 2553. DOI: 10.1182/blood.v114.22.2553.2553.Peer-Reviewed Original ResearchSickle cell anemia patientsSickle cell anemiaSoluble adhesion moleculesHigher serum levelsMedical historyAnemia patientsAdhesion moleculesEndothelial dysfunctionSerum levelsICAM-1Aspartate transferaseSteady-state sickle cell anemia patientsDensity lipoproteinControl groupVCAM-1 adhesion moleculesLipid metabolismChronic clinical complicationsVaso-occlusive painSurface adhesion molecule expressionNeutrophil adhesion moleculesSoluble ICAM-1Complete medical historyAdhesion molecule expressionHigh-density lipoproteinLow-density lipoprotein