2023
Neurofeedback for obsessive compulsive disorder: A randomized, double-blind trial
Rance M, Zhao Z, Zaboski B, Kichuk S, Romaker E, Koller W, Walsh C, Harris-Starling C, Wasylink S, Adams T, Gruner P, Pittenger C, Hampson M. Neurofeedback for obsessive compulsive disorder: A randomized, double-blind trial. Psychiatry Research 2023, 328: 115458. PMID: 37722238, PMCID: PMC10695074, DOI: 10.1016/j.psychres.2023.115458.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderAnterior prefrontal cortexControl groupDouble-blind clinical trialDouble-blind trialPrimary outcome measureCompulsive disorderHarm/checkingMechanism of actionYale-Brown ObsessiveSecondary outcomesSessions of neurofeedbackActive groupClinical trialsOutcome measuresPrimary symptomsSymptom ScaleObsessive-compulsive symptomsPrefrontal cortexSymptomsTraining protocolGreater reductionSignificant differencesPatientsSham feedback
2016
Neural Correlates of Success and Failure Signals During Neurofeedback Learning
Radua J, Stoica T, Scheinost D, Pittenger C, Hampson M. Neural Correlates of Success and Failure Signals During Neurofeedback Learning. Neuroscience 2016, 378: 11-21. PMID: 27063101, PMCID: PMC5537049, DOI: 10.1016/j.neuroscience.2016.04.003.Peer-Reviewed Original ResearchConceptsNeurofeedback signalFeedback learningMedial prefrontal/anterior cingulate cortexFeedback-driven learningPrecuneus/posterior cingulateClear adaptive valueDefault mode networkLevel-dependent responsesAnterior cingulate cortexOperant conditioning paradigmReduction of anxietyNeurofeedback learningNeural correlatesSignals of failureNeural processesNeurofeedback interventionConditioning paradigmNeurofeedback experimentsMode networkOrbitofrontal cortexCingulate cortexPosterior cingulateFunctional runsAbstract representationLearning
2013
Orbitofrontal cortex neurofeedback produces lasting changes in contamination anxiety and resting-state connectivity
Scheinost D, Stoica T, Saksa J, Papademetris X, Constable RT, Pittenger C, Hampson M. Orbitofrontal cortex neurofeedback produces lasting changes in contamination anxiety and resting-state connectivity. Translational Psychiatry 2013, 3: e250-e250. PMID: 23632454, PMCID: PMC3641411, DOI: 10.1038/tp.2013.24.Peer-Reviewed Original ResearchConceptsResting-state connectivityContamination anxietyBrain regionsNF trainingBrain connectivityResting-state functional connectivityFunctional magnetic resonance imaging (fMRI) neurofeedbackPotential of neurofeedbackRelevant brain networksResting-state fMRIDorsolateral prefrontal cortexTarget brain regionsBrain functional architectureUseful therapyLimbic circuitryMatched subjectsOrbitofrontal regionsOrbitofrontal cortexFunctional connectivityPrefrontal cortexHuman emotionsFeedback control tasksSubclinical anxietyAnxiety regulationBrain networks