2023
Protocol description for a randomized controlled trial of fMRI neurofeedback for tics in adolescents with Tourette Syndrome
Awasthi J, Harris-Starling C, Kalvin C, Pittman B, Park H, Bloch M, Fernandez T, Sukhodolsky D, Hampson M. Protocol description for a randomized controlled trial of fMRI neurofeedback for tics in adolescents with Tourette Syndrome. Psychiatry Research Neuroimaging 2023, 336: 111692. PMID: 37673711, PMCID: PMC10722977, DOI: 10.1016/j.pscychresns.2023.111692.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentHumansMagnetic Resonance ImagingNeurofeedbackRandomized Controlled Trials as TopicTic DisordersTicsTourette SyndromeConceptsTourette syndromeFunctional magnetic resonance imagingStudy protocolChronic tic disorderSupplementary motor areaLower functional connectivityMagnetic resonance imagingResearch study protocolLarge trialsClinical trialsTic disordersMotor areaBrain areasControl groupResonance imagingBrain regionsNew trialsFunctional connectivityNeurofeedback interventionFMRI neurofeedbackNF protocolTrialsNF studiesSyndromeInterventionAmygdala downregulation training using fMRI neurofeedback in post-traumatic stress disorder: a randomized, double-blind trial
Zhao Z, Duek O, Seidemann R, Gordon C, Walsh C, Romaker E, Koller W, Horvath M, Awasthi J, Wang Y, O’Brien E, Fichtenholtz H, Hampson M, Harpaz-Rotem I. Amygdala downregulation training using fMRI neurofeedback in post-traumatic stress disorder: a randomized, double-blind trial. Translational Psychiatry 2023, 13: 177. PMID: 37230984, PMCID: PMC10209552, DOI: 10.1038/s41398-023-02467-6.Peer-Reviewed Original ResearchMeSH KeywordsAmygdalaDown-RegulationHumansMagnetic Resonance ImagingNeurofeedbackStress Disorders, Post-TraumaticConceptsPost-traumatic stress disorderControl groupAmygdala activityPTSD treatmentDouble-blind clinical trialStress disorderDouble-blind trialSecondary outcome measurementsTrauma recallNeurofeedback trainingGreater improvementAmygdala controlsPotential clinical applicationsSymptom scoresActive groupClinical trialsTreatment successOutcome measurementsTrauma scriptsSymptom reductionNeurofeedback interventionPTSD symptomsFMRI neurofeedbackAmygdalaNeural markers
2022
HALO: A software tool for real‐time head alignment in the MR scanner
Zhao Z, Galiana G, Zillo C, Camarro T, Qiu M, Papademetris X, Hampson M. HALO: A software tool for real‐time head alignment in the MR scanner. Magnetic Resonance In Medicine 2022, 89: 1506-1513. PMID: 36426774, PMCID: PMC10753491, DOI: 10.1002/mrm.29535.Peer-Reviewed Original Research
2019
Randomized, Sham-Controlled Trial of Real-Time Functional Magnetic Resonance Imaging Neurofeedback for Tics in Adolescents With Tourette Syndrome
Sukhodolsky DG, Walsh C, Koller WN, Eilbott J, Rance M, Fulbright RK, Zhao Z, Bloch MH, King R, Leckman JF, Scheinost D, Pittman B, Hampson M. Randomized, Sham-Controlled Trial of Real-Time Functional Magnetic Resonance Imaging Neurofeedback for Tics in Adolescents With Tourette Syndrome. Biological Psychiatry 2019, 87: 1063-1070. PMID: 31668476, PMCID: PMC7015800, DOI: 10.1016/j.biopsych.2019.07.035.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentCross-Over StudiesHumansMagnetic Resonance ImagingNeurofeedbackSeverity of Illness IndexTicsTourette SyndromeConceptsSupplementary motor areaYale Global Tic Severity ScaleFunctional magnetic resonanceTic Severity ScaleReal-time functional magnetic resonanceTourette syndromeSeverity ScaleYale Global Tic Severity Scale-Total Tic ScoreTotal tic scorePrimary outcome measureSham control conditionReduction of ticsMagnetic resonanceSecondary outcomesSessions of neurofeedbackCrossover studyTic symptomsTic scoreOutcome measuresMotor areaSecondary measuresTic severityReal neurofeedbackEnd pointNeurofeedback intervention
2018
Time course of clinical change following neurofeedback
Rance M, Walsh C, Sukhodolsky DG, Pittman B, Qiu M, Kichuk SA, Wasylink S, Koller WN, Bloch M, Gruner P, Scheinost D, Pittenger C, Hampson M. Time course of clinical change following neurofeedback. NeuroImage 2018, 181: 807-813. PMID: 29729393, PMCID: PMC6454268, DOI: 10.1016/j.neuroimage.2018.05.001.Peer-Reviewed Original ResearchConceptsClinical changesSymptom changeTime courseBrain functionNeurofeedback studiesPotential clinical toolCrossover designControl interventionsReal neurofeedbackClinical toolTime pointsClinical populationsNeurofeedback effectsInterventionNeurofeedback sessionsNeurofeedbackCurrent brain stateWeeksBrain statesNew studiesCourseSessionsSymptoms
2016
Neural Correlates of Success and Failure Signals During Neurofeedback Learning
Radua J, Stoica T, Scheinost D, Pittenger C, Hampson M. Neural Correlates of Success and Failure Signals During Neurofeedback Learning. Neuroscience 2016, 378: 11-21. PMID: 27063101, PMCID: PMC5537049, DOI: 10.1016/j.neuroscience.2016.04.003.Peer-Reviewed Original ResearchConceptsNeurofeedback signalFeedback learningMedial prefrontal/anterior cingulate cortexFeedback-driven learningPrecuneus/posterior cingulateClear adaptive valueDefault mode networkLevel-dependent responsesAnterior cingulate cortexOperant conditioning paradigmReduction of anxietyNeurofeedback learningNeural correlatesSignals of failureNeural processesNeurofeedback interventionConditioning paradigmNeurofeedback experimentsMode networkOrbitofrontal cortexCingulate cortexPosterior cingulateFunctional runsAbstract representationLearning
2013
Orbitofrontal cortex neurofeedback produces lasting changes in contamination anxiety and resting-state connectivity
Scheinost D, Stoica T, Saksa J, Papademetris X, Constable RT, Pittenger C, Hampson M. Orbitofrontal cortex neurofeedback produces lasting changes in contamination anxiety and resting-state connectivity. Translational Psychiatry 2013, 3: e250-e250. PMID: 23632454, PMCID: PMC3641411, DOI: 10.1038/tp.2013.24.Peer-Reviewed Original ResearchMeSH KeywordsAnxietyFeedback, PhysiologicalFemaleFrontal LobeFunctional NeuroimagingHumansLimbic SystemMagnetic Resonance ImagingMaleNerve NetPrefrontal CortexConceptsResting-state connectivityContamination anxietyBrain regionsNF trainingBrain connectivityResting-state functional connectivityFunctional magnetic resonance imaging (fMRI) neurofeedbackPotential of neurofeedbackRelevant brain networksResting-state fMRIDorsolateral prefrontal cortexTarget brain regionsBrain functional architectureUseful therapyLimbic circuitryMatched subjectsOrbitofrontal regionsOrbitofrontal cortexFunctional connectivityPrefrontal cortexHuman emotionsFeedback control tasksSubclinical anxietyAnxiety regulationBrain networks
2010
Functional connectivity between task-positive and task-negative brain areas and its relation to working memory performance
Hampson M, Driesen N, Roth JK, Gore JC, Constable RT. Functional connectivity between task-positive and task-negative brain areas and its relation to working memory performance. Magnetic Resonance Imaging 2010, 28: 1051-1057. PMID: 20409665, PMCID: PMC2936669, DOI: 10.1016/j.mri.2010.03.021.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainBrain MappingFemaleFrontal LobeHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMemoryMiddle AgedModels, StatisticalNormal DistributionConceptsDorsolateral prefrontal cortexCognitive tasksBrain areasCognitive functionPrefrontal cortexTask-negative regionsWhole-brain correlationMedial frontal cortexAnterior cingulate cortexGroup-level analysisMemory performanceFunctional brainCingulate cortexFunctional connectivityFrontal cortexFunctional connectionsCortexTaskRelationshipNegative correlationValidityConnectivityBrainFindingsRegression
2008
Brain Areas Coactivating with Motor Cortex During Chronic Motor Tics and Intentional Movements
Hampson M, Tokoglu F, King RA, Constable RT, Leckman JF. Brain Areas Coactivating with Motor Cortex During Chronic Motor Tics and Intentional Movements. Biological Psychiatry 2008, 65: 594-599. PMID: 19111281, PMCID: PMC2679868, DOI: 10.1016/j.biopsych.2008.11.012.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainFemaleHumansIntentionMagnetic Resonance ImagingMaleMotor CortexMovementTic DisordersTourette SyndromeConceptsMotor cortexSupplementary motor areaControl subjectsBrain areasMotor ticsTic disordersTic movementsMotor areaTic-like movementsHealthy control subjectsChronic tic disorderNormal control subjectsChronic motor ticsNovel intervention strategiesFunctional neuroimaging studiesTic executionSevere ticsIntentional movementPatient's ticsMotor regionsPremonitory urgesBrain activity patternsAdult subjectsTic generationCortex
2006
Connectivity–behavior analysis reveals that functional connectivity between left BA39 and Broca's area varies with reading ability
Hampson M, Tokoglu F, Sun Z, Schafer RJ, Skudlarski P, Gore JC, Constable RT. Connectivity–behavior analysis reveals that functional connectivity between left BA39 and Broca's area varies with reading ability. NeuroImage 2006, 31: 513-519. PMID: 16497520, DOI: 10.1016/j.neuroimage.2005.12.040.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrain MappingFrontal LobeFunctional LateralityHumansMagnetic Resonance ImagingReadingReference Values
2002
Detection of functional connectivity using temporal correlations in MR images
Hampson M, Peterson BS, Skudlarski P, Gatenby JC, Gore JC. Detection of functional connectivity using temporal correlations in MR images. Human Brain Mapping 2002, 15: 247-262. PMID: 11835612, PMCID: PMC6872035, DOI: 10.1002/hbm.10022.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrain MappingFemaleFrontal LobeHumansMagnetic Resonance ImagingMaleMiddle AgedMotor CortexTemporal Lobe