2011
Eisosome-driven plasma membrane organization is mediated by BAR domains
Ziółkowska NE, Karotki L, Rehman M, Huiskonen JT, Walther TC. Eisosome-driven plasma membrane organization is mediated by BAR domains. Nature Structural & Molecular Biology 2011, 18: 854-856. PMID: 21685922, DOI: 10.1038/nsmb.2080.Peer-Reviewed Original ResearchMeSH KeywordsCell MembraneMembrane ProteinsMultigene FamilyPhosphoproteinsPhylogenyProtein Structure, TertiarySaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSequence Analysis, Protein
2009
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M. Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions. Science 2009, 325: 834-840. PMID: 19608861, DOI: 10.1126/science.1175371.Peer-Reviewed Original ResearchMeSH KeywordsAcetylationAmino Acid MotifsBenzamidesCell Line, TumorCell NucleusCell Physiological PhenomenaCytoplasmEnzyme InhibitorsHistone Deacetylase InhibitorsHistone DeacetylasesHumansHydroxamic AcidsLysineMass SpectrometryMetabolic Networks and PathwaysMitochondriaMultiprotein ComplexesProtein Processing, Post-TranslationalProtein Structure, TertiaryProteinsProteomeProteomicsPyridinesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsVorinostatConceptsLysine acetylationCellular rolesPosttranslational modificationsCyclin-dependent kinase Cdc28Phosphorylation-dependent interactionReversible posttranslational modificationDiverse cellular processesMajor cellular functionsTarget protein complexesMajor posttranslational modificationLarge macromolecular complexesLysine acetylation sitesChromatin remodelingActin nucleationNuclear transportProtein complexesCellular functionsCellular processesAcetylation sitesMacromolecular complexesAcetylation changesGene expressionCell cycleDeacetylase inhibitorsAcetylation