2012
Immunotherapy for Cutaneous T-Cell Lymphoma
Modi B, Foss F, Edelson R, Girardi M. Immunotherapy for Cutaneous T-Cell Lymphoma. Contemporary Hematology 2012, 307-316. DOI: 10.1007/978-1-62703-170-7_18.Peer-Reviewed Original ResearchCutaneous T-cell lymphomaT-cell lymphomaToll-like receptor agonistsEffector T cell activityImmune effector mechanismsT cell activityGoal of therapyCytokine-based therapiesHistone deacetylase inhibitorsClinical responseMost patientsImmunotherapeutic approachesInterleukin-12Receptor agonistEffector mechanismsInterleukin-2Therapeutic approachesImmune functionDeacetylase inhibitorsTherapyCTCLPatientsLymphomaAttractive targetImmunotherapy
2008
FDG-PET/CT for the Evaluation of Response to Therapy of Cutaneous T-cell Lymphoma to Vorinostat (Suberoylanilide Hydroxamic Acid, SAHA) in a Phase II Trial
Kuo PH, Carlson KR, Christensen I, Girardi M, Heald PW. FDG-PET/CT for the Evaluation of Response to Therapy of Cutaneous T-cell Lymphoma to Vorinostat (Suberoylanilide Hydroxamic Acid, SAHA) in a Phase II Trial. Molecular Imaging And Biology 2008, 10: 306-314. PMID: 18665425, DOI: 10.1007/s11307-008-0161-4.Peer-Reviewed Original ResearchConceptsCutaneous T-cell lymphomaFDG PET/CTPhase II trialParticular positron emission tomographyT-cell lymphomaII trialNodal diseaseInitial PET/CT scanPET/CT scansEarly clinical trialsEvaluation of responseHistone deacetylase inhibitorsAlters gene transcriptionPositron emission tomographyFDG uptakeCutaneous lesionsFDG-PETPrognostic valueFuture trialsClinical trialsConclusionFurther studiesCell lymphomaCT scanDeacetylase inhibitorsHDAC inhibitors