2015
Quantifying hyperoxia-mediated damage to mammalian respiratory cilia-driven fluid flow using particle tracking velocimetry optical coherence tomography
Gamm UA, Huang BK, Syed M, Zhang X, Bhandari V, Choma MA. Quantifying hyperoxia-mediated damage to mammalian respiratory cilia-driven fluid flow using particle tracking velocimetry optical coherence tomography. Journal Of Biomedical Optics 2015, 20: 080505-080505. PMID: 26308164, PMCID: PMC4874052, DOI: 10.1117/1.jbo.20.8.080505.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsHyperbaric OxygenationHyperoxiaImage Interpretation, Computer-AssistedMiceMucusReproducibility of ResultsRespiratory MucosaRheologySensitivity and SpecificityTomography, Optical CoherenceConceptsOptical coherence tomographyMouse tracheaCoherence tomographyDrug-mediated modulationIntensive care unitRisk-benefit profileRespiratory failureCare unitOxygen supplementationRespiratory mucosaRespiratory epitheliumIndispensable treatmentImpaired capacityClinical useHyperoxiaTracheaFlow quantificationTomographyTreatmentDamagePatientsMucosaSupplementationEpitheliumQuantitative optical coherence tomography imaging of intermediate flow defect phenotypes in ciliary physiology and pathophysiology
Huang BK, Gamm UA, Jonas S, Khokha MK, Choma MA. Quantitative optical coherence tomography imaging of intermediate flow defect phenotypes in ciliary physiology and pathophysiology. Journal Of Biomedical Optics 2015, 20: 030502-030502. PMID: 25751026, PMCID: PMC4352652, DOI: 10.1117/1.jbo.20.3.030502.Peer-Reviewed Original ResearchAnimalsCiliaMucociliary ClearancePhenotypeSerotoninSignal TransductionTomography, Optical CoherenceXenopus
2014
Resolving directional ambiguity in dynamic light scattering-based transverse motion velocimetry in optical coherence tomography.
Huang BK, Choma MA. Resolving directional ambiguity in dynamic light scattering-based transverse motion velocimetry in optical coherence tomography. Optics Letters 2014, 39: 521-4. PMID: 24487855, PMCID: PMC4174353, DOI: 10.1364/ol.39.000521.Peer-Reviewed Original ResearchConceptsTotal transverseDirectional velocityFunction calibrationTomography approachDirectional ambiguityScan axisDirectional velocity componentsThree-component velocimetryOptical coherence tomographyTransverse planeVelocity componentsLongitudinal angleCoherence tomographyDoppler velocimetryVelocimetryTransversePlane
2010
Physiological homology between Drosophila melanogaster and vertebrate cardiovascular systems
Choma MA, Suter MJ, Vakoc BJ, Bouma BE, Tearney GJ. Physiological homology between Drosophila melanogaster and vertebrate cardiovascular systems. Disease Models & Mechanisms 2010, 4: 411-420. PMID: 21183476, PMCID: PMC3097462, DOI: 10.1242/dmm.005231.Peer-Reviewed Original Research
2005
Spectral-domain phase microscopy.
Choma MA, Ellerbee AK, Yang C, Creazzo TL, Izatt JA. Spectral-domain phase microscopy. Optics Letters 2005, 30: 1162-4. PMID: 15945141, DOI: 10.1364/ol.30.001162.Peer-Reviewed Original ResearchConceptsSpectral domain phase microscopyShot-noise limitPhase-sensitive techniqueNanometer-scale motionCoherence gatingBroadband interferometryDisplacement sensitivityPhase microscopyPhase informationOptical coherence tomographyCoherence tomographyFunctional extensionAttractive techniqueInterferometryLiving cellsCellular motionMotionCellular dynamicsMicroscopyMeasurementsTechniqueGating