2016
Investigation of peanut oral immunotherapy with CpG/peanut nanoparticles in a murine model of peanut allergy
Srivastava KD, Siefert A, Fahmy TM, Caplan MJ, Li XM, Sampson HA. Investigation of peanut oral immunotherapy with CpG/peanut nanoparticles in a murine model of peanut allergy. Journal Of Allergy And Clinical Immunology 2016, 138: 536-543.e4. PMID: 27130858, DOI: 10.1016/j.jaci.2016.01.047.Peer-Reviewed Original ResearchConceptsPeanut oral immunotherapyOral peanut challengesPeanut-specific immunotherapyPeanut allergyOral immunotherapyPeanut challengeSymptom scoresRecall responsesMurine modelSplenocyte culturesHistamine levelsPeanut-specific serum IgEC3H/HeJ miceIFN-γ levelsPlasma histamine levelsVehicle control animalsCytokine recall responsesLower symptom scoresBody temperatureCurrent clinical approachesOral sensitizationWeekly gavageIgG2a levelsSublingual immunotherapySerum IgE
2015
Investigation of Peanut Oral Immunotherapy Using CpG/Peanut-Nanoparticles in a Murine Model of Peanut Allergy
Srivastava K, Siefert A, Fahmy T, Caplan M, Li X, Sampson H. Investigation of Peanut Oral Immunotherapy Using CpG/Peanut-Nanoparticles in a Murine Model of Peanut Allergy. Journal Of Allergy And Clinical Immunology 2015, 135: ab235. DOI: 10.1016/j.jaci.2014.12.1701.Peer-Reviewed Original ResearchPeanut allergyMurine model