2024
WHO global research priorities for antimicrobial resistance in human health
Bertagnolio S, Dobreva Z, Centner C, Olaru I, Donà D, Burzo S, Huttner B, Chaillon A, Gebreselassie N, Wi T, Hasso-Agopsowicz M, Allegranzi B, Sati H, Ivanovska V, Kothari K, Balkhy H, Cassini A, Hamers R, Van Weezenbeek K, Collaborators W, Aanensen D, Alanio A, Alastruey-Izquierdo A, Alemayehu T, Al-Hasan M, Allegaert K, Al-Maani A, Al-Salman J, Alshukairi A, Amir A, Applegate T, Araj G, Villalobos M, Årdal C, Ashiru-Oredope D, Ashley E, Babin F, Bachmann L, Bachmann T, Baker K, Balasegaram M, Bamford C, Baquero F, Barcelona L, Bassat Q, Bassetti M, Basu S, Beardsley J, Vásquez G, Berkley J, Bhatnagar A, Bielicki J, Bines J, Bongomin F, Bonomo R, Bradley J, Bradshaw C, Brett A, Brink A, Brown C, Brown J, Buising K, Carson C, Carvalho A, Castagnola E, Cavaleri M, Cecchini M, Chabala C, Chaisson R, Chakrabarti A, Chandler C, Chandy S, Charani E, Chen L, Chiara F, Chowdhary A, Chua A, Chuki P, Chun D, Churchyard G, Cirillo D, Clack L, Coffin S, Cohn J, Cole M, Conly J, Cooper B, Corso A, Cosgrove S, Cox H, Daley C, Darboe S, Darton T, Davies G, de Egea V, Dedeić-Ljubović A, Deeves M, Denkinger C, Dillon J, Dramowski A, Eley B, Esposito S, Essack S, Farida H, Farooqi J, Feasey N, Ferreyra C, Fifer H, Finlayson H, Frick M, Gales A, Galli L, Gandra S, Gerber J, Giske C, Gordon B, Govender N, Guessennd N, Guindo I, Gurbanova E, Gwee A, Hagen F, Harbarth S, Haze J, Heim J, Hendriksen R, Heyderman R, Holt K, Hönigl M, Hook E, Hope W, Hopkins H, Hughes G, Ismail G, Issack M, Jacobs J, Jasovský D, Jehan F, Pearson A, Jones M, Joshi M, Kapil A, Kariuki S, Karkey A, Kearns G, Keddy K, Khanna N, Kitamura A, Kolho K, Kontoyiannis D, Kotwani A, Kozlov R, Kranzer K, Kularatne R, Lahra M, Langford B, Laniado-Laborin R, Larsson J, Lass-Flörl C, Le Doare K, Lee H, Lessa F, Levin A, Limmathurotsakul D, Lincopan N, Vecchio A, Lodha R, Loeb M, Longtin Y, Lye D, Mahmud A, Manaia C, Manderson L, Mareković I, Marimuthu K, Martin I, Mashe T, Mei Z, Meis J, De Melo F, Mendelson M, Miranda A, Moore D, Morel C, Moremi N, Moro M, Moussy F, Mshana S, Mueller A, Ndow F, Nicol M, Nunn A, Obaro S, Obiero C, Okeke I, Okomo U, Okwor T, Oladele R, Omulo S, Ondoa P, de Canese J, Ostrosky-Zeichner L, Padoveze M, Pai M, Park B, Parkhill J, Parry C, Peeling R, Peixe L, Perovic O, Pettigrew M, Principi N, Pulcini C, Puspandari N, Rawson T, Reddy D, Reddy K, Redner P, Tudela J, Rodríguez-Baño J, Van Katwyk S, Roilides E, Rollier C, Rollock L, Ronat J, Ruppe E, Sadarangani M, Salisbury D, Salou M, Samison L, Sanguinetti M, Sartelli M, Schellack N, Schouten J, Schwaber M, Seni J, Senok A, Shafer W, Shakoor S, Sheppard D, Shin J, Sia S, Sievert D, Singh I, Singla R, Skov R, Soge O, Sprute R, Srinivasan A, Srinivasan S, Sundsfjord A, Tacconelli E, Tahseen S, Tangcharoensathien V, Tängdén T, Thursky K, Thwaites G, de Souza Peral R, Tong D, Tootla H, Tsioutis C, Turner K, Turner P, Omar S, van de Sande W, van den Hof S, van Doorn R, Veeraraghavan B, Verweij P, Wahyuningsih R, Wang H, Warris A, Weinstock H, Wesangula E, Whiley D, White P, Williams P, Xiao Y, Moscoso M, Yang H, Yoshida S, Yu Y, Żabicka D, Zignol M, Rudan I. WHO global research priorities for antimicrobial resistance in human health. The Lancet Microbe 2024, 5: 100902. PMID: 39146948, PMCID: PMC11543637, DOI: 10.1016/s2666-5247(24)00134-4.Peer-Reviewed Original ResearchAntimicrobial resistanceTreatment of antimicrobial-resistant infectionsConsequences of antimicrobial resistanceAntimicrobial resistance epidemiologyAntimicrobial-resistant infectionsDrug-resistant pathogensAntimicrobial resistance dynamicsResearch prioritiesComprehensive scoping reviewGeneration of evidenceGlobal research prioritiesScoping reviewWHOKnowledge gapsExpert inputResearch agendaHealthBurdenPathogensFungal pathogensPolicy translationTuberculosisDiagnosisInfection
2018
Persistence of Moraxella catarrhalis in Chronic Obstructive Pulmonary Disease and Regulation of the Hag/MID Adhesin
Murphy TF, Brauer AL, Pettigrew MM, LaFontaine ER, Tettelin H. Persistence of Moraxella catarrhalis in Chronic Obstructive Pulmonary Disease and Regulation of the Hag/MID Adhesin. The Journal Of Infectious Diseases 2018, 219: 1448-1455. PMID: 30496439, PMCID: PMC6467191, DOI: 10.1093/infdis/jiy680.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseObstructive pulmonary diseaseM. catarrhalisPulmonary diseaseMoraxella catarrhalisPersistent strainsDuration of persistenceHuman airwaysCatarrhalisCessation of expressionAirwayMajor pathogenPatientsBacterial pathogensDiseaseVirulence-associated phenotypesAdultsCollected strainsMost strainsExpressionHuman cellsPathogensPathogenesisPersistenceMonths
2014
Detection of livestock-associated methicillin-resistant Staphylococcus aureus among swine workers in Romania
Huang E, Gurzau AE, Hanson BM, Kates AE, Smith TC, Pettigrew MM, Spinu M, Rabinowitz PM. Detection of livestock-associated methicillin-resistant Staphylococcus aureus among swine workers in Romania. Journal Of Infection And Public Health 2014, 7: 323-332. PMID: 24821273, DOI: 10.1016/j.jiph.2014.03.008.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgricultureAnimal HusbandryAnimalsCarrier StateFemaleHumansLivestockMaleMethicillin-Resistant Staphylococcus aureusMiddle AgedMolecular TypingNasal MucosaOccupational ExposureOropharynxPrevalenceRomaniaStaphylococcal InfectionsStaphylococcal Protein ASurveys and QuestionnairesSwineConceptsLivestock-associated methicillin-resistant Staphylococcus aureusMethicillin-resistant Staphylococcus aureusLA-MRSASwine workersLivestock workersSpa type t034Commercial pig farmsCommunity-associated MRSA strainsPig farmsDevastating pathogenStaphylococcus aureusFarmsCommercial movementsSubstantial health risksMRSA carriersMRSA colonizationHigh morbidityRisk factorsMRSA strainsHealth statusBiosafety practicesCommunity contactsProduction facilitiesPathogensEpidemiology
2009
Multilocus Sequence Typing and Pulsed Field Gel Electrophoresis of Otitis Media Causing Pathogens
Thomas JC, Pettigrew MM. Multilocus Sequence Typing and Pulsed Field Gel Electrophoresis of Otitis Media Causing Pathogens. Methods In Molecular Biology 2009, 493: 179-190. PMID: 18839348, PMCID: PMC3581352, DOI: 10.1007/978-1-59745-523-7_11.Peer-Reviewed Original ResearchConceptsOtitis mediaMolecular epidemiologyMultilocus sequence typingMoraxella catarrhalisHaemophilus influenzaeStreptococcus pneumoniaeSequence typingPulsed-Field Gel ElectrophoresisEpidemiologyBacterial pathogensField gel electrophoresisType of studyResearch settingsCharacterization of isolatesPathogensCatarrhalisInfluenzaePneumoniae