2007
Identification of Yeast IQGAP (Iqg1p) as an Anaphase-Promoting-Complex Substrate and Its Role in Actomyosin-Ring-Independent Cytokinesis
Ko N, Nishihama R, Tully GH, Ostapenko D, Solomon MJ, Morgan DO, Pringle JR. Identification of Yeast IQGAP (Iqg1p) as an Anaphase-Promoting-Complex Substrate and Its Role in Actomyosin-Ring-Independent Cytokinesis. Molecular Biology Of The Cell 2007, 18: 5139-5153. PMID: 17942599, PMCID: PMC2096582, DOI: 10.1091/mbc.e07-05-0509.Peer-Reviewed Original ResearchMeSH KeywordsActomyosinAmino Acid MotifsAnaphase-Promoting Complex-CyclosomeCytokinesisGene Expression Regulation, FungalMicrotubule-Associated ProteinsMutationMyosin Heavy ChainsPhenotypeProtein BindingRas GTPase-Activating ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSubstrate SpecificityUbiquitinUbiquitin-Protein Ligase ComplexesConceptsActomyosin ringAPC/C mutantsAPC/C functionSeptin-dependent mannerAnaphase-promoting complexYeast Saccharomyces cerevisiaeOnset of cytokinesisDeletion of genesBud neckMitotic exitAPC/Mitotic cyclinsSaccharomyces cerevisiaeSeptum formationIqg1pCytokinesisNovel recognition sequenceC mutantsNonessential componentsSame phenotypeRecognition sequenceLate G1Rich mediumStrain backgroundComplex substrates
1996
The Cdk-Activating Kinase (CAK) from Budding Yeast
Kaldis P, Sutton A, Solomon M. The Cdk-Activating Kinase (CAK) from Budding Yeast. Cell 1996, 86: 553-564. PMID: 8752210, DOI: 10.1016/s0092-8674(00)80129-4.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceCDC28 Protein Kinase, S cerevisiaeCDC2-CDC28 KinasesCell CycleCell Cycle ProteinsCyclin BCyclin-Dependent Kinase 2Cyclin-Dependent Kinase-Activating KinaseCyclin-Dependent KinasesCyclinsFungal ProteinsGenes, FungalMolecular Sequence DataMolecular WeightPhosphorylationProtein Serine-Threonine KinasesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSequence AlignmentSequence Homology, Amino AcidStructure-Activity RelationshipConceptsCDK-Activating KinaseBasal transcription factorsTemperature-sensitive mutationProtein kinase activityCyclin-dependent kinasesCell cycle progressionGenetic interactionsMitotic cyclinsTranscription factorsS. cerevisiaeKinase activityCycle progressionCell extractsG2 delayKinaseAltered expressionE. coliIntriguing possibilityPhosphorylationCyclinFull activityCak1pClb2TFIIHCak1