1997
B Lymphocytes as Autoantigen‐presenting Cells in the Amplification of Autoimmunitya
ROTH R, GEE R, MAMULA M. B Lymphocytes as Autoantigen‐presenting Cells in the Amplification of Autoimmunitya. Annals Of The New York Academy Of Sciences 1997, 815: 88-100. PMID: 9186642, DOI: 10.1111/j.1749-6632.1997.tb52047.x.Peer-Reviewed Original ResearchConceptsB cell-deficient miceCell-deficient miceNaive T cellsT cellsSelf antigensIL-4IL-5B cellsB7-2 costimulatory moleculesAutoantigen-presenting cellsAutoreactive T cellsT cell toleranceAntigen-presenting cellsCytokine mRNA responsesB cell subsetsNaive lymphAutoimmune responseCell subsetsCostimulatory moleculesAntigen presentationCytokine mRNAIFN-gammaB lymphocytesCell toleranceMRNA response
1994
The expression of self antigenic determinants: implications for tolerance and autoimmunity
Mamula M, Craft J. The expression of self antigenic determinants: implications for tolerance and autoimmunity. Current Opinion In Immunology 1994, 6: 882-886. PMID: 7536009, DOI: 10.1016/0952-7915(94)90008-6.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigen PresentationAntigen-Presenting CellsAutoantigensAutoimmunityEpitopesHumansImmune ToleranceT-LymphocytesConceptsAntigen-presenting cellsT cellsSelf peptidesSelf antigenic determinantsT cell responsesPathogenesis of autoimmunityMajor histocompatibility moleculesNormal lymphocytesAntigen processingAntigenic determinantsHistocompatibility moleculesAutoimmunityCell surface proteinsNormal pathwayCellsPeptidesLymphocytesPathogenesis
1993
Do B cells drive the diversification of immune responses?
Mamula M, Janeway C. Do B cells drive the diversification of immune responses? Trends In Immunology 1993, 14: 151-152. PMID: 8098941, DOI: 10.1016/0167-5699(93)90274-o.Peer-Reviewed Original Research
1991
Induction of autoreactive B cells allows priming of autoreactive T cells.
Lin R, Mamula M, Hardin J, Janeway C. Induction of autoreactive B cells allows priming of autoreactive T cells. Journal Of Experimental Medicine 1991, 173: 1433-1439. PMID: 1851798, PMCID: PMC2190847, DOI: 10.1084/jem.173.6.1433.Peer-Reviewed Original Research