2024
An innovative approach to aligning healthcare with what matters most to patients: A hybrid type 1 trial protocol of patient priorities care for older adults with multiple chronic conditions
Naik A, Shanahan M, Dindo L, Mecca M, Arney J, Amspoker A, Wydermyer S, Banks J, Street R, Kiefer L, Zenoni M, Rosen T, Gonzalez R, Catic A, Fried T. An innovative approach to aligning healthcare with what matters most to patients: A hybrid type 1 trial protocol of patient priorities care for older adults with multiple chronic conditions. Contemporary Clinical Trials 2024, 143: 107613. PMID: 38914308, DOI: 10.1016/j.cct.2024.107613.Peer-Reviewed Original ResearchMultiple chronic conditionsHealth priorityOlder adultsCare approachChronic conditionsTreatment burdenPriorities of older adultsPatient-centered care approachPatient Priorities CarePatients' health prioritiesPrimary care providersVeterans Affairs Medical CenterHealth care decisionsAffairs Medical CenterHigh treatment burdenComplexity of patientsRandomized controlled trialsPrimary careUsual carePriority careCare providersImplementation outcomesCare decisionsCare optionsAssessor-blinded
2014
Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults: The LIFE Study Randomized Clinical Trial
Pahor M, Guralnik JM, Ambrosius WT, Blair S, Bonds DE, Church TS, Espeland MA, Fielding RA, Gill TM, Groessl EJ, King AC, Kritchevsky SB, Manini TM, McDermott MM, Miller ME, Newman AB, Rejeski WJ, Sink KM, Williamson JD. Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults: The LIFE Study Randomized Clinical Trial. JAMA 2014, 311: 2387-2396. PMID: 24866862, PMCID: PMC4266388, DOI: 10.1001/jama.2014.5616.Peer-Reviewed Original ResearchConceptsMajor mobility disabilityPhysical activity groupModerate-intensity physical activity programHealth education groupPhysical activity programHealth education programsMobility disabilityOlder adultsActivity programClinical trialsActivity groupPhysical activityIncident major mobility disabilityShort Physical Performance BatteryPersistent mobility disabilityPhysical activity preventsEducation groupSerious adverse eventsIndependent risk factorPhysical Performance BatteryDefinitive clinical trialsStructured physical activityVulnerable older adultsAdverse eventsLifestyle intervention