Sevoflurane 0.25 MAC Preferentially Affects Higher Order Association Areas: A Functional Magnetic Resonance Imaging Study in Volunteers
Ramani R, Qiu M, Constable RT. Sevoflurane 0.25 MAC Preferentially Affects Higher Order Association Areas: A Functional Magnetic Resonance Imaging Study in Volunteers. Anesthesia & Analgesia 2007, 105: 648-655. PMID: 17717218, PMCID: PMC2716177, DOI: 10.1213/01.ane.0000277496.12747.29.Peer-Reviewed Original ResearchConceptsRegional cerebral blood flowFunctional magnetic resonance imagingMAC sevofluraneMotor activation taskAssociation cortexMemory-related regionsAssociation areasVolatile anestheticsVisual cortexBaseline regional cerebral blood flowHigher-order association areasMagnetic resonance imaging studyHigher-order association corticesCerebral blood flowActivation taskSupplementary motor areaPrimary cortical regionsSecondary visual cortexPrimary visual cortexResonance imaging studyFunctional magnetic resonance imaging studyMagnetic resonance imagingArterial spin labeling techniqueASA ISubanesthetic doses