2008
Advances in Radiotherapy for Lung Cancer
Decker R, Wilson L. Advances in Radiotherapy for Lung Cancer. Seminars In Respiratory And Critical Care Medicine 2008, 29: 285-290. PMID: 18506666, DOI: 10.1055/s-2008-1076748.Peer-Reviewed Original ResearchConceptsLung cancerAggressive local therapyEarly lung tumorsProphylactic cranial irradiationPositron emission tomographic imagingDefinitive treatment optionCell lung cancerRole of radiosurgeryOngoing clinical investigationsEmission tomographic imagingNormal tissue toxicityCranial irradiationPalliative therapyPostoperative radiationLocal therapyLung irradiationAdvanced tumorsTreatment optionsCancer helpLung tumorsRadiation therapyClinical investigationRadiation treatment planningTissue toxicityTherapy
1997
Total skin electron beam therapy followed by adjuvant psoralen/ultraviolet-A light in the management of patients with T1 and T2 cutaneous T-cell lymphoma (mycosis fungoides)
Quirós P, Jones G, Kacinski B, Braverman I, Heald P, Edelson R, Wilson L. Total skin electron beam therapy followed by adjuvant psoralen/ultraviolet-A light in the management of patients with T1 and T2 cutaneous T-cell lymphoma (mycosis fungoides). International Journal Of Radiation Oncology • Biology • Physics 1997, 38: 1027-1035. PMID: 9276369, DOI: 10.1016/s0360-3016(97)00127-2.Peer-Reviewed Original ResearchConceptsTotal skin electron beam therapyDisease-free survivalT2 patientsCrude relapse rateAdjuvant therapyOverall survivalElectron beam therapyRelapse rateEntire cohortMedian disease-free survivalCutaneous T-cell lymphomaBeam therapySalvage of recurrencesAdjuvant systemic therapyEarly-stage patientsManagement of patientsT-cell lymphomaTopical nitrogen mustardDays/weekCombination of therapiesGy/dayTreatments/weekPUVA patientsMedian followSalvage therapyBioreductive alkylating agent porfiromycin in combination with radiation therapy for the management of squamous cell carcinoma of the head and neck
Haffty B, Son Y, Wilson L, Papac R, Fischer D, Rockwell S, Sartorelli A, Ross D, Sasaki C, Fischer J. Bioreductive alkylating agent porfiromycin in combination with radiation therapy for the management of squamous cell carcinoma of the head and neck. International Journal Of Cancer 1997, 5: 235-245. PMID: 9372546, DOI: 10.1002/(sici)1520-6823(1997)5:5<235::aid-roi4>3.0.co;2-z.Peer-Reviewed Original ResearchConceptsSquamous cell carcinomaWhite blood cell countPhase I trialCell carcinomaRadiation therapyMitomycin CNonhematological toxicitiesI trialStage III/IV squamous cell carcinomaCourse of RTTotal median doseAcceptable toxicity profilePhase III trialsCurrent ongoing trialsDisease survival ratesDaily radiation therapyBlood cell countHypoxic cell cytotoxinActuarial survivalHemoglobin nadirsAdvanced diseaseMedian doseIII trialsOngoing trialsMultiinstitutional trialTreatment of recurrent pelvic and selected primary gynecologic malignancies with 241Am
Chung J, Roberts K, Peschel R, Nath R, Pourang R, Kacinski B, Wilson L. Treatment of recurrent pelvic and selected primary gynecologic malignancies with 241Am. International Journal Of Cancer 1997, 5: 227-234. PMID: 9372545, DOI: 10.1002/(sici)1520-6823(1997)5:5<227::aid-roi3>3.0.co;2-#.Peer-Reviewed Original ResearchConceptsRecurrent pelvic malignanciesPrimary gynecologic malignanciesPrimary radiotherapySurgical salvageMicroscopic diseasePelvic malignanciesPostoperative radiotherapyGynecologic malignanciesUltimate local control rateExternal beam radiation therapyGross primary tumorMedian patient ageLocal control rateTreatment of recurrentBeam radiation therapyMicroscopic residuumTreatment intentPatient ageSurgical resectionCurative therapyGynecologic tumorsGynecologic cancerControl ratePrimary tumorRadiation therapy
1995
Subareolar breast cancer: Long-term results with conservative surgery and radiation therapy
Haffty B, Wilson L, Smith R, Fischer D, Beinfield M, Ward B, McKhann C. Subareolar breast cancer: Long-term results with conservative surgery and radiation therapy. International Journal Of Radiation Oncology • Biology • Physics 1995, 33: 53-57. PMID: 7642431, DOI: 10.1016/0360-3016(95)00165-u.Peer-Reviewed Original ResearchMeSH KeywordsBreast NeoplasmsCombined Modality TherapyFemaleFollow-Up StudiesHumansMiddle AgedNeoplasm Recurrence, LocalNipplesPrognosisRetrospective StudiesTreatment OutcomeConceptsEntire nipple areolar complexSubareolar breast cancersNipple-areolar complexEarly-stage breast cancerMajority of patientsStage breast cancerAreolar complexBreast cancerConservative surgeryRadiation therapyMedian doseConservative managementRelative contraindicationAxillary lymph node dissectionDistant disease-free survivalYale-New Haven HospitalTotal median doseAdjuvant systemic therapyLymph node dissectionRegional nodal irradiationDisease-free survivalRecurrence-free survivalSubset of patientsTime of surgeryLong-term results
1994
Adjuvant systemic chemotherapy and hormonal therapy. Effect on local recurrence in the conservatively treated breast cancer patient
Haffty B, Wilmarth L, Wilson L, Fischer D, Beinfield M, McKhann C. Adjuvant systemic chemotherapy and hormonal therapy. Effect on local recurrence in the conservatively treated breast cancer patient. Cancer 1994, 73: 2543-2548. PMID: 8174051, DOI: 10.1002/1097-0142(19940515)73:10<2543::aid-cncr2820731015>3.0.co;2-7.Peer-Reviewed Original ResearchConceptsAdjuvant systemic therapyAdjuvant systemic chemotherapyLower relapse rateMajority of patientsSystemic therapySystemic chemotherapyRadiation therapyBreast relapseHormonal therapyLymph nodesRelapse rateSignificant independent prognostic factorAdjuvant hormonal therapyNegative lymph nodesCox regression analysisIndependent prognostic factorBreast cancer patientsAxillary dissectionLocal relapseLocal recurrencePatient agePrognostic factorsCancer patientsRetrospective analysisIntact breast
1993
Conservative surgery and radiation in the treatment of synchronous ipsilateral breast cancers
Wilson L, Beinfield M, McKhann C, Haffty B. Conservative surgery and radiation in the treatment of synchronous ipsilateral breast cancers. Cancer 1993, 72: 137-142. PMID: 8389664, DOI: 10.1002/1097-0142(19930701)72:1<137::aid-cncr2820720126>3.0.co;2-e.Peer-Reviewed Original ResearchConceptsIpsilateral breast cancerConservative surgeryRadiation therapyRecurrence rateBreast cancerBreast recurrence rateChest wall progressionIpsilateral breast recurrenceActuarial survival rateEvidence of diseaseLocal recurrence rateManagement of patientsSubsequent local recurrenceInvasive lobular histologyBreast recurrenceLobular histologyMedian doseMetastatic diseaseLocal recurrenceThird patientRegional lymphaticsSeparate lesionsSingle lesionSame breastPatients