2024
Lessons from Clinical Communications for Explainable AI
Menon A, Omar Z, Nahar N, Papademetris X, Fiellin L, Kästner C. Lessons from Clinical Communications for Explainable AI. Proceedings Of The AAAI/ACM Conference On AI, Ethics, And Society 2024, 7: 958-970. DOI: 10.1609/aies.v7i1.31695.Peer-Reviewed Original ResearchSystematic Review of Interventions with Some School Involvement for School Refusal in High School–Age Adolescents
Fernandes C, Kannoth S, Boomer T, Hieftje K, Fiellin L. Systematic Review of Interventions with Some School Involvement for School Refusal in High School–Age Adolescents. Children & Schools 2024, 46: 85-95. DOI: 10.1093/cs/cdae003.Peer-Reviewed Original ResearchSchool-based componentCognitive-behavioral therapySchool-aged adolescentsSystematic reviewSystematic Reviews of InterventionsQuality appraisal toolDevelopment of interventionsReviews of InterventionsRandomized controlled trialsChronic absenteeismPublic health concernAppraisal ToolEmotional distressStudy designEligibility criteriaControlled trialsHigh school-aged adolescentsHealth concernQuality studiesSchool settingsInterventionAbsenteeismHigher ratesDuplicate recordsAdolescents
2023
Identifying Game-Based Digital Biomarkers of Cognitive Risk for Adolescent Substance Misuse: Protocol for a Proof-of-Concept Study
Aneni K, Chen C, Meyer J, Cho Y, Lipton Z, Kher S, Jiao M, de la Vega I, Umutoni F, McDougal R, Fiellin L. Identifying Game-Based Digital Biomarkers of Cognitive Risk for Adolescent Substance Misuse: Protocol for a Proof-of-Concept Study. JMIR Research Protocols 2023, 12: e46990. PMID: 37995115, PMCID: PMC10704313, DOI: 10.2196/46990.Peer-Reviewed Original ResearchA Video Game Intervention to Prevent Opioid Misuse Among Older Adolescents: Development and Preimplementation Study
Aneni K, Fernandes C, Hoerner L, Szapary C, Boomer T, Fiellin L. A Video Game Intervention to Prevent Opioid Misuse Among Older Adolescents: Development and Preimplementation Study. JMIR Serious Games 2023, 11: e46912. PMID: 37921851, PMCID: PMC10656656, DOI: 10.2196/46912.Peer-Reviewed Original ResearchOpioid misuseVideo game interventionMental health crisisMental healthPreventive interventionsOlder adolescentsGame interventionHealth Belief ModelMental health risksHealth crisisComorbid conditionsCurrent opioidFocus groupsSubstance misuseMental disordersProtective factorsBelief ModelInterventionDigital interventionsAdolescentsHealth risksFormative workHealthMisuseRiskA Serious Video Game Targeting HIV Testing and Counseling: A Randomized Controlled Trial
Boomer T, Larkin K, Duncan L, Fernandes C, Fiellin L. A Serious Video Game Targeting HIV Testing and Counseling: A Randomized Controlled Trial. Journal Of Adolescent Health 2023, 74: 252-259. PMID: 37815773, PMCID: PMC10841098, DOI: 10.1016/j.jadohealth.2023.08.016.Peer-Reviewed Original ResearchHIV testingPrimary outcome measureSecondary outcomesControlled TrialsHIV statusParental consent formsVideo game interventionOutcome measuresAge groupsConsent formTrialsMonthsWeeksGame interventionControl conditionOutcomesParticipantsCounselingStudy conditionsAdolescentsGroupSubjects ANOVASessionsParticipants' attitudesA digital health game to prevent opioid misuse and promote mental health in adolescents in school-based health settings: Protocol for the PlaySmart game randomized controlled trial
Boomer T, Hoerner L, Fernandes C, Maslar A, Aiudi S, Kyriakides T, Fiellin L. A digital health game to prevent opioid misuse and promote mental health in adolescents in school-based health settings: Protocol for the PlaySmart game randomized controlled trial. PLOS ONE 2023, 18: e0291298. PMID: 37683047, PMCID: PMC10490848, DOI: 10.1371/journal.pone.0291298.Peer-Reviewed Original ResearchConceptsMental health outcomesOpioid misuseMental healthHealth gamesHealth outcomesMeasures of depressionMental health symptomsGreater riskHelp-seeking behaviorSecondary outcome measuresCritical developmental periodOpioid use disorderPerception of riskRisk of initiationHealth symptomsSchool gradesProfessional helpMisusing opioidsPrimary outcomeDevelopmental periodAdolescentsOutcome measuresSubstance misuseUse disordersHealth settingsMultidisciplinary Strategies for Preventing Opioid Misuse and Escalation by Targeting Mental Health Symptoms and Conditions
Yule A, Fernandes C, Stormshak E, Yang Y, Shelley L, Fiellin L, Larkin K, Ridenour T, Saavedra L, Kelleher K, Feng X, Walton M, Bonar E. Multidisciplinary Strategies for Preventing Opioid Misuse and Escalation by Targeting Mental Health Symptoms and Conditions. Prevention Science 2023, 24: 77-87. PMID: 37266870, PMCID: PMC10236392, DOI: 10.1007/s11121-023-01556-8.Peer-Reviewed Original ResearchConceptsMental health conditionsOpioid use disorderOpioid misuseMental health symptomsHealth conditionsHealth symptomsMental healthSubstance useEarly substance usePrevention interventionsHigh riskUse disordersMultidisciplinary strategyPrevention effortsIdentification of youthNational InstituteSymptomsHealthInterventionRiskMisuseAssociationLeveraging the Full Continuum of Care to Prevent Opioid Use Disorder
Cance J, Adams E, D’Amico E, Palimaru A, Fernandes C, Fiellin L, Bonar E, Walton M, Komro K, Knight D, Knight K, Rao V, Youn S, Saavedra L, Ridenour T, Deeds B. Leveraging the Full Continuum of Care to Prevent Opioid Use Disorder. Prevention Science 2023, 24: 30-39. PMID: 37261635, PMCID: PMC10689575, DOI: 10.1007/s11121-023-01545-x.Peer-Reviewed Original ResearchConceptsOpioid use disorderContinuum of careUse disordersPrevention programsDisorder prevention programUnique risk profileOpioid misuseBaseline riskUnique cohortPrevention continuumRisk profileUniversal preventionYoung adultsCareOpioidsOlder adolescentsPreventionDisordersFull continuumMost substancesCohortSubstancesEvaluating the validity of game-based assessments measuring cognitive function among children and adolescents: A systematic review and meta-analysis
Aneni K, Gomati de la Vega I, Jiao M, Funaro M, Fiellin L. Evaluating the validity of game-based assessments measuring cognitive function among children and adolescents: A systematic review and meta-analysis. Progress In Brain Research 2023, 279: 1-36. PMID: 37661161, DOI: 10.1016/bs.pbr.2023.02.002.Peer-Reviewed Original Research30. The Association Between Extracurricular Activities and Perception of Risk of Harm from Adolescent Binge Drinking
Szapary C, Meyer J, Fernandes C, Pendergrass T, Fiellin L, Aneni K, Ermel A, Brown D, Kahn J. 30. The Association Between Extracurricular Activities and Perception of Risk of Harm from Adolescent Binge Drinking. Journal Of Adolescent Health 2023, 72: s24. DOI: 10.1016/j.jadohealth.2022.11.048.Peer-Reviewed Original ResearchMixed methods evaluation of vaping and tobacco product use prevention interventions among youth in the Florida 4-H program
Bteddini D, LeLaurin J, Chi X, Hall J, Theis R, Gurka M, Lee J, Mobley E, Khalil G, Polansky C, Kellner A, Fahnlander A, Kelder S, Fiellin L, Gutter M, Shenkman E, Salloum R. Mixed methods evaluation of vaping and tobacco product use prevention interventions among youth in the Florida 4-H program. Addictive Behaviors 2023, 141: 107637. PMID: 36753933, DOI: 10.1016/j.addbeh.2023.107637.Peer-Reviewed Original ResearchConceptsE-cigarette useE-cigarettesTobacco productsTobacco-related knowledgeRural settingsNovel prevention programFlavored tobacco productsDifferent recruitment methodsGroup intervention sessionsMixed-methods evaluationOutcome measuresPrevention interventionsControl groupTobacco knowledgePrevention programsFurther evaluationPilot studyIntervention sessionsBreathRisk perceptionInterventionRecruitment methodsScheduling of sessionsFocus group discussionsParticipants
2022
Accelerating Solutions for the Overdose Crisis: an Effectiveness-Implementation Hybrid Protocol for the HEAL Prevention Cooperative
Patel S, Cance J, Bonar E, Carter P, Dickerson D, Fiellin L, Fernandes C, Palimaru A, Boomer T, Saldana L, Singh R, Tinius E, Walton M, Youn S, Young S, Philbrick S, Lambdin B. Accelerating Solutions for the Overdose Crisis: an Effectiveness-Implementation Hybrid Protocol for the HEAL Prevention Cooperative. Prevention Science 2022, 24: 40-49. PMID: 36399222, PMCID: PMC9673891, DOI: 10.1007/s11121-022-01465-2.Peer-Reviewed Original ResearchA Pilot Randomized Controlled Trial to Evaluate a Cognitive Behavioral Videogame Intervention: empowerED
Fernandes C, Deng Y, Tran A, Hieftje K, Boomer T, Taylor C, Fiellin L. A Pilot Randomized Controlled Trial to Evaluate a Cognitive Behavioral Videogame Intervention: empowerED. Games For Health Journal 2022, 12: 42-52. PMID: 36350349, PMCID: PMC10331148, DOI: 10.1089/g4h.2021.0118.Peer-Reviewed Original ResearchConceptsCognitive reappraisalBeliefs/attitudesVideogame interventionEmotion regulation strategiesCognitive reappraisal skillsSchool climateYouth mental health needsPilot RCTHigh school settingReappraisal skillsMental health needsRegulation strategiesYouth perceptionsPreliminary effectsSchool settingsControl conditionSkill developmentHealthy developmentPreliminary efficacyPerceptionReappraisalYouthAttitudesInterventionHealth needsMethodological Strategies for Prospective Harmonization of Studies: Application to 10 Distinct Outcomes Studies of Preventive Interventions Targeting Opioid Misuse
Ridenour TA, Cruden G, Yang Y, Bonar EE, Rodriguez A, Saavedra LM, Hussong AM, Walton MA, Deeds B, Ford JL, Knight DK, Haggerty KP, Stormshak E, Kominsky TK, Ahrens KR, Woodward D, Feng X, Fiellin LE, Wilens TE, Klein DJ, Fernandes CS. Methodological Strategies for Prospective Harmonization of Studies: Application to 10 Distinct Outcomes Studies of Preventive Interventions Targeting Opioid Misuse. Prevention Science 2022, 24: 16-29. PMID: 35976525, PMCID: PMC9935745, DOI: 10.1007/s11121-022-01412-1.Peer-Reviewed Original Research
2021
Effectiveness of a Web-Based Tobacco Product use Prevention Videogame Intervention on Young Adolescents’ Beliefs and Knowledge
Hieftje KD, Fernandes CF, Lin IH, Fiellin LE. Effectiveness of a Web-Based Tobacco Product use Prevention Videogame Intervention on Young Adolescents’ Beliefs and Knowledge. Substance Use & Addiction Journal 2021, 42: 47-53. PMID: 31825759, DOI: 10.1080/08897077.2019.1691128.Peer-Reviewed Original ResearchConceptsTobacco product useVideogame interventionE-cigarettesElectronic cigarettesProduct useMcNemar testKnowledge questionsSingle group pre-post studyTobacco product initiationPre-post studySignificant differencesCigarette smokingProduct initiationTobacco useUse preventionHealthy beliefsPromising effectsKnowledge surveyInterventionVapingCigarettesDescriptive statisticsAdolescentsCorrect answersAge differences
2020
A quasi-experimental test of a virtual reality game prototype for adolescent E-Cigarette prevention
Weser VU, Duncan LR, Pendergrass TM, Fernandes CS, Fiellin LE, Hieftje KD. A quasi-experimental test of a virtual reality game prototype for adolescent E-Cigarette prevention. Addictive Behaviors 2020, 112: 106639. PMID: 32920455, DOI: 10.1016/j.addbeh.2020.106639.Peer-Reviewed Original ResearchConceptsSocial norm perceptionsGame prototypePerceptions of harmNorm perceptionsQuasi-experimental testPaired-samples t-testParticipants' enjoymentSocial normsPreliminary impactPerceptionEffect sizeE-cigarette preventionVirtual reality hardwarePost designAdolescentsSatisfactionVRDependent variableAttitudesHarm perceptionsE-cigarettesGameEnjoymentParticipantsGameplayIntegrated stepped alcohol treatment for patients with HIV and at-risk alcohol use: a randomized trial
Edelman EJ, Maisto SA, Hansen NB, Cutter CJ, Dziura J, Deng Y, Fiellin LE, O’Connor P, Bedimo R, Gibert CL, Marconi VC, Rimland D, Rodriguez-Barradas MC, Simberkoff MS, Tate JP, Justice AC, Bryant KJ, Fiellin DA. Integrated stepped alcohol treatment for patients with HIV and at-risk alcohol use: a randomized trial. Addiction Science & Clinical Practice 2020, 15: 28. PMID: 32727618, PMCID: PMC7388231, DOI: 10.1186/s13722-020-00200-y.Peer-Reviewed Original ResearchConceptsRisk alcohol useAlcohol useAlcohol treatmentHealth of patientsEvidence-based strategiesWeek 24HIV outcomesRoutine careTelephone boosterPhysician managementEnhancement therapyHIVPWHPatientsTrialsTarget populationTreatmentAlcohol-related researchMulti-pronged approachOutcomesParticipantsInsufficient numberTherapyPopulationMethodsInVideogame intervention to encourage HIV testing and counseling among adolescents
Pendergrass T, Hieftje K, Duncan L, Fiellin L. Videogame intervention to encourage HIV testing and counseling among adolescents. MHealth 2020, 6: 26-26. PMID: 32632364, PMCID: PMC7327291, DOI: 10.21037/mhealth.2020.01.05.Peer-Reviewed Original ResearchHIV testingNew HIV casesVideogame interventionCrucial public health concernPublic health concernUndiagnosed HIVHIV casesHIV preventionMajority of adolescentsFocus groupsPositive diagnosisHIVHealth concernPilot studyStrong misperceptionAdolescentsRisk reductionHigh ratePretest-posttest designSocial stigmaBehavior changeIncorrect knowledgeOne-fifthInterventionAssessment measures
2019
Predictors of initiation of and retention on medications for alcohol use disorder among people living with and without HIV
Oldfield BJ, McGinnis KA, Edelman EJ, Williams EC, Gordon AJ, Akgün K, Crystal S, Fiellin LE, Gaither JR, Goulet JL, Korthuis PT, Marshall BDL, Justice AC, Bryant K, Fiellin DA, Kraemer KL. Predictors of initiation of and retention on medications for alcohol use disorder among people living with and without HIV. Journal Of Substance Use And Addiction Treatment 2019, 109: 14-22. PMID: 31856946, PMCID: PMC6982467, DOI: 10.1016/j.jsat.2019.11.002.Peer-Reviewed Original ResearchConceptsAlcohol use disorderUse disordersHIV statusUninfected individualsVeterans Aging Cohort Study (VACS) dataEvidence-based medicationsNew alcohol use disorderPrevalence of initiationMultivariable logistic regressionPredictors of initiationFacility-level predictorsCohort study dataMedication initiationPrescription fillsMultivariable analysisBlack raceTreatment gapDecreased oddsNew diagnosisPLWHOlder ageLogistic regressionMedicationsHIVSpecific subpopulationsIntegrated stepped alcohol treatment for patients with HIV and liver disease: A randomized trial
Edelman EJ, Maisto SA, Hansen NB, Cutter CJ, Dziura J, Deng Y, Fiellin LE, O'Connor PG, Bedimo R, Gibert CL, Marconi VC, Rimland D, Rodriguez-Barradas MC, Simberkoff MS, Tate JP, Justice AC, Bryant KJ, Fiellin DA. Integrated stepped alcohol treatment for patients with HIV and liver disease: A randomized trial. Journal Of Substance Use And Addiction Treatment 2019, 106: 97-106. PMID: 31540617, PMCID: PMC7244228, DOI: 10.1016/j.jsat.2019.08.007.Peer-Reviewed Original Research