2019
Time Requirements of Paper-Based Clinical Workflows and After-Hours Documentation in a Multispecialty Academic Ophthalmology Practice
Baxter S, Gali H, Huang A, Millen M, El-Kareh R, Nudleman E, Robbins S, Heichel C, Camp A, Korn B, Lee J, Kikkawa D, Longhurst C, Chiang M, Hribar M, Ohno-Machado L. Time Requirements of Paper-Based Clinical Workflows and After-Hours Documentation in a Multispecialty Academic Ophthalmology Practice. American Journal Of Ophthalmology 2019, 206: 161-167. PMID: 30910517, PMCID: PMC6755078, DOI: 10.1016/j.ajo.2019.03.014.Peer-Reviewed Original ResearchConceptsPatient encountersNew patient evaluationsClinical workflowElectronic health record useOutpatient ophthalmology clinicHigh clinical volumeAcademic ophthalmology departmentsAcademic ophthalmology practicePaper-based documentationAge 43.9Postoperative visitRoutine followClinic hoursOphthalmology clinicOphthalmology departmentPatient evaluationOphthalmology practiceOutcome measurementsPatientsPatient careHours workRecord useOphthalmologistsClinical volumeTotal time
2017
Mechanisms to protect the privacy of families when using the transmission disequilibrium test in genome-wide association studies
Wang M, Ji Z, Wang S, Kim J, Yang H, Jiang X, Ohno-Machado L. Mechanisms to protect the privacy of families when using the transmission disequilibrium test in genome-wide association studies. Bioinformatics 2017, 33: 3716-3725. PMID: 29036461, PMCID: PMC5860319, DOI: 10.1093/bioinformatics/btx470.Peer-Reviewed Original ResearchA Predictive Model for Extended Postanesthesia Care Unit Length of Stay in Outpatient Surgeries
Gabriel R, Waterman R, Kim J, Ohno-Machado L. A Predictive Model for Extended Postanesthesia Care Unit Length of Stay in Outpatient Surgeries. Anesthesia & Analgesia 2017, 124: 1529-1536. PMID: 28079580, DOI: 10.1213/ane.0000000000001827.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedAged, 80 and overAmbulatory Surgical ProceduresAnesthesiaChildChild, PreschoolCritical CareFemaleForecastingHumansHypertensionInfantInfant, NewbornIntensive Care UnitsLength of StayLogistic ModelsMaleMiddle AgedModels, StatisticalObesity, MorbidPostoperative CareRisk FactorsROC CurveYoung AdultConceptsPACU lengthPostanesthesia care unit lengthPrimary anesthesia typePostanesthesia care unitHosmer-Lemeshow testLogistic regression modelsAnesthesia typeMorbid obesityCare unitHL testOutpatient surgeryOutpatient procedureSingle institutionHigher oddsNonsignificant P valuesStayPatientsSurgical specialtiesROC curveGood calibrationCharacteristic curveExcellent discriminationAUC valuesP-valueBackward elimination
2016
Building a Natural Language Processing Tool to Identify Patients With High Clinical Suspicion for Kawasaki Disease from Emergency Department Notes
Doan S, Maehara C, Chaparro J, Lu S, Liu R, Graham A, Berry E, Hsu C, Kanegaye J, Lloyd D, Ohno‐Machado L, Burns J, Tremoulet A, Group T. Building a Natural Language Processing Tool to Identify Patients With High Clinical Suspicion for Kawasaki Disease from Emergency Department Notes. Academic Emergency Medicine 2016, 23: 628-636. PMID: 26826020, PMCID: PMC5031359, DOI: 10.1111/acem.12925.Peer-Reviewed Original ResearchConceptsDiagnosis of KDKawasaki diseaseED notesHigh suspicionPediatric ED patientsSerious cardiac complicationsHigh clinical suspicionEmergency department patientsManual chart reviewCardiac complicationsChart reviewClinical suspicionFebrile illnessDepartment patientsED patientsElectronic health record systemsEmergency departmentClinical signsDiagnostic criteriaHealth record systemsPatientsClinical termsSuspicionDiagnosisRecord system
2013
Differential Expression of miR-145 in Children with Kawasaki Disease
Shimizu C, Kim J, Stepanowsky P, Trinh C, Lau H, Akers J, Chen C, Kanegaye J, Tremoulet A, Ohno-Machado L, Burns J. Differential Expression of miR-145 in Children with Kawasaki Disease. PLOS ONE 2013, 8: e58159. PMID: 23483985, PMCID: PMC3590129, DOI: 10.1371/journal.pone.0058159.Peer-Reviewed Original ResearchMeSH KeywordsArteriesBase SequenceChildChild, PreschoolCluster AnalysisGene Expression RegulationHumansInfantMicroRNAsModels, BiologicalMolecular Sequence DataMucocutaneous Lymph Node SyndromeReal-Time Polymerase Chain ReactionSequence AlignmentSequence Analysis, DNASignal TransductionTransforming Growth Factor betaConceptsTGF-β pathwayGene expressionMiR-145Small non-coding RNAsKawasaki disease pathogenesisExtracellular vesiclesSmall RNA speciesPost-transcriptional levelDiscovery of microRNAsKawasaki diseaseNon-coding RNAsExpression of genesDisease pathogenesisSmall extracellular vesiclesSmall RNAsRNA speciesTarget genesTop pathwaysVascular smooth muscle cellsPathway analysisDifferentiation of neutrophilsDifferential expressionMicroRNAsArterial wallGeneration of myofibroblasts
2003
An Epicurean learning approach to gene-expression data classification
Albrecht A, Vinterbo S, Ohno-Machado L. An Epicurean learning approach to gene-expression data classification. Artificial Intelligence In Medicine 2003, 28: 75-87. PMID: 12850314, DOI: 10.1016/s0933-3657(03)00036-8.Peer-Reviewed Original Research
2002
Open source handheld-based EMR for paramedics working in rural areas.
Anantraman V, Mikkelsen T, Khilnani R, Kumar V, Pentland A, Ohno-Machado L. Open source handheld-based EMR for paramedics working in rural areas. AMIA Annual Symposium Proceedings 2002, 12-6. PMID: 12463777, PMCID: PMC2244537.Peer-Reviewed Original Research
2000
Decision trees and fuzzy logic: a comparison of models for the selection of measles vaccination strategies in Brazil.
Ohno-Machado L, Lacson R, Massad E. Decision trees and fuzzy logic: a comparison of models for the selection of measles vaccination strategies in Brazil. AMIA Annual Symposium Proceedings 2000, 625-9. PMID: 11079959, PMCID: PMC2244038.Peer-Reviewed Original Research
1993
Prognostic classification for aids patients in Brazil
Ohno-Machado L. Prognostic classification for aids patients in Brazil. Journal Of Medical Systems 1993, 17: 163-172. PMID: 8254260, DOI: 10.1007/bf00996941.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeAdolescentAdultAgedAIDS-Related Opportunistic InfectionsBrazilCause of DeathChildChild, PreschoolCross-Sectional StudiesDeveloping CountriesDiscriminant AnalysisFemaleHospitalizationHumansIncidenceInfantInfant, NewbornMaleMiddle AgedNeoplasmsSurvival RateConceptsHospitalized AIDS patientsPrognosis of deathHistory of transfusionGroup IV patientsNumber of infectionsEsophageal candidiasisIV patientsAIDS patientsFirst manifestationAID patientsRisk groupsPrognostic classificationPrognostic variablesSurvival ratePatientsFinal discriminant functionInfectionDiseaseDeathAnalysis groupHospitalizationTransfusionPrognosisGroupCandidiasis