2015
A system to build distributed multivariate models and manage disparate data sharing policies: implementation in the scalable national network for effectiveness research
Meeker D, Jiang X, Matheny M, Farcas C, D’Arcy M, Pearlman L, Nookala L, Day M, Kim K, Kim H, Boxwala A, El-Kareh R, Kuo G, Resnic F, Kesselman C, Ohno-Machado L. A system to build distributed multivariate models and manage disparate data sharing policies: implementation in the scalable national network for effectiveness research. Journal Of The American Medical Informatics Association 2015, 22: 1187-1195. PMID: 26142423, PMCID: PMC4639714, DOI: 10.1093/jamia/ocv017.Peer-Reviewed Original ResearchConceptsFederated networkData sharing policiesParallel computation methodSharing policiesPolicy management systemData exchange policiesData storage requirementsWeb servicesNetwork queriesQuery functionalityComputation resourcesFederated modelGraphical interfaceData transportCentralized networkStorage requirementsNetwork participantsManagement systemQueriesNetworkComputation methodNew featuresMultivariate statistical estimationDifferent state lawsImportant new feature
2004
Protecting patient privacy by quantifiable control of disclosures in disseminated databases
Ohno-Machado L, Silveira P, Vinterbo S. Protecting patient privacy by quantifiable control of disclosures in disseminated databases. International Journal Of Medical Informatics 2004, 73: 599-606. PMID: 15246040, DOI: 10.1016/j.ijmedinf.2004.05.002.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsAnonymous TestingConfidentialityDatabases as TopicDisclosureHumansMedical Records Systems, ComputerizedPrivacyConceptsSensitive patient dataPattern recognition algorithmsLevel of confidentialitySensitive dataPrivacy protectionSensitive informationDisseminated dataRecognition algorithmDegree of anonymityPatient privacyAlgorithmPrivacyPatient dataDatabaseAnonymizationQuantifiable controlPublic health purposesConfidentialityInformationAnonymityHealth care organizationsHealth purposesCare organizationsCommon practiceAmbiguation
1999
Decision support for clinical trial eligibility determination in breast cancer.
Ohno-Machado L, Wang S, Mar P, Boxwala A. Decision support for clinical trial eligibility determination in breast cancer. AMIA Annual Symposium Proceedings 1999, 340-4. PMID: 10566377, PMCID: PMC2232554.Peer-Reviewed Original ResearchConceptsClinical trial eligibility determinationPhysician Data Query databaseEligibility criteriaClinical trialsBreast cancerMetastatic breast cancerPrimary care providersClinical trial protocolTrial protocolFree-text eligibility criteriaCare providersClinical informationEligibility informationPatientsEligibility determinationPatient informationPhase IICancerTrialsOrder of likelihoodNumerical scoreCriteria
1998
Improving machine learning performance by removing redundant cases in medical data sets.
Ohno-Machado L, Fraser H, Ohrn A. Improving machine learning performance by removing redundant cases in medical data sets. AMIA Annual Symposium Proceedings 1998, 523-7. PMID: 9929274, PMCID: PMC2232167.Peer-Reviewed Original ResearchMeSH KeywordsArea Under CurveArtificial IntelligenceDatabases as TopicHumansMyocardial InfarctionNeural Networks, ComputerRandom AllocationROC Curve
1997
Sequential versus standard neural networks for pattern recognition: An example using the domain of coronary heart disease
Ohno-Machado L, Musen M. Sequential versus standard neural networks for pattern recognition: An example using the domain of coronary heart disease. Computers In Biology And Medicine 1997, 27: 267-281. PMID: 9303265, DOI: 10.1016/s0010-4825(97)00008-5.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAlgorithmsArea Under CurveBlood PressureBody WeightCause of DeathCholesterolCoronary DiseaseDatabases as TopicDemographyDisease ProgressionDisease-Free SurvivalEvaluation Studies as TopicFollow-Up StudiesForecastingHumansMaleMiddle AgedModels, CardiovascularNeural Networks, ComputerOutcome Assessment, Health CarePattern Recognition, AutomatedPrognosisROC CurveSmokingSurvival AnalysisTime FactorsConceptsNeural network modelNeural networkSequential neural network modelsTime-oriented dataNetwork modelNeural network architectureStandard neural networkSequential neural networkNeural network systemRecognition of patternsNetwork architecturePattern recognitionUnseen casesNetwork systemTest setSingle pointResearch data basesData basesNetworkMedical researchersSuch modelsRecognitionBackpropagationSetArchitecture